Research ArticleOriginal Article
Open Access

The effect of poor glycemic control on cognitive function in children and adolescents with type 1 diabetes mellitus

A single-center cross-sectional study (2019–2020)

Safiah M. Al-Shehaili, Seham S. Al-Johani, Nora T. Al-Sarhan, Aisha A. Al-Anazi, Faten F. Al-Mijmaj, Wadha N. Al-Qhatani, Lama M. Al-Nasser, Dania R. Al-Yami and Amal S. Al-Razooq
Saudi Medical Journal October 2023, 44 (10) 1006-1012; DOI: https://doi.org/10.15537/smj.2023.44.20230327

References

  1. 1.↵
    1. Patterson CC,
    2. Karuranga S,
    3. Salpea P,
    4. Saeedi P,
    5. Dahlquist G,
    6. Soltesz G, et al.
    Worldwide estimates of incidence, prevalence and mortality of type 1 diabetes in children and adolescents: results from the international diabetes federation diabetes atlas, 9th edition. Diabetes Res Clin Pract 2019; 157: 107842.
    OpenUrlCrossRefPubMed
  2. 2.↵
    1. Robert AA,
    2. Al-Dawish A,
    3. Mujammami M,
    4. Dawish MA.
    Type 1 diabetes mellitus in Saudi Arabia: A soaring epidemic. Int J Pediatr 2018; 2018: 9408370.
    OpenUrlPubMed
  3. 3.↵
    1. Donaghue KC,
    2. Marcovecchio ML,
    3. Wadwa RP,
    4. Chew EY,
    5. Wong TY,
    6. Calliari LE, et al.
    ISPAD clinical practice consensus guidelines 2018: Microvascular and macrovascular complications in children and adolescents. Pediatr Diabetes 2018; 19: 262–274.
    OpenUrlPubMed
  4. 4.↵
    1. Cacciatore M,
    2. Grasso EA,
    3. Tripodi R,
    4. Chiarelli F.
    Impact of glucose metabolism on the developing brain. Front Endocrinol 2022; 13: 1047545.
    OpenUrl
  5. 5.↵
    1. DiMeglio LA,
    2. Acerini CL,
    3. Codner E,
    4. Craig ME,
    5. Hofer SE,
    6. Pillay K, et al.
    ISPAD Clinical Practice Consensus Guidelines 2018: Glycemic control targets and glucose monitoring for children, adolescents, and young adults with diabetes. Pediatr Diabetes 2018; 19: 105–114.
    OpenUrlCrossRefPubMed
  6. 6.
    1. Farag S.
    Stanford–Binet Intelligence test: standardized Arabic version. Cairo, Egypt: Anglo Press; 2011. p. 12.
  7. 7.↵
    1. Cameron FJ,
    2. Northam EA,
    3. Ryan CM.
    The effect of type 1 diabetes on the developing brain. Lancet Child Adolesc Health 2019; 3: 427–436.
    OpenUrl
  8. 8.↵
    1. He J,
    2. Ryder AG,
    3. Li S,
    4. Liu W,
    5. Zhu X.
    Glycemic extremes are related to cognitive dysfunction in children with type 1 diabetes: A meta-analysis. J Diabetes Investig 2018; 9: 1342–1353.
    OpenUrl
  9. 9.↵
    1. Holmes CS,
    2. Richman LC.
    Cognitive profiles of children with insulin-dependent diabetes. J Dev Behav Pediatr 1985; 6: 323–326.
    OpenUrlPubMedWeb of Science
  10. 10.
    1. Nevo-Shenker M,
    2. Shalitin S.
    The impact of hypo- and hyperglycemia on cognition and brain development in young children with type 1 diabetes. Horm Res Paediatr 2021; 94: 115–123.
    OpenUrl
  11. 11.↵
    1. Northam EA,
    2. Rankins D,
    3. Cameron FJ.
    Therapy insight: the impact of type 1 diabetes on brain development and function. Nat Clin Pract Neurol 2006; 2: 78–86.
    OpenUrlCrossRefPubMed
  12. 12.↵
    1. He J,
    2. Li S,
    3. Liu F,
    4. Zheng H,
    5. Yan X,
    6. Xie Y, et al.
    Glycemic control is related to cognitive dysfunction in Chinese children with type 1 diabetes mellitus. J Diabetes 2018; 10: 948–957.
    OpenUrlPubMed
  13. 13.↵
    1. Desrocher M,
    2. Rovet J.
    Neurocognitive correlates of type 1 diabetes mellitus in childhood. Child Neuropsychol 2004; 10: 36–52.
    OpenUrlCrossRefPubMedWeb of Science
  14. 14.↵
    1. Ack M,
    2. Miller I,
    3. Weil WB Jr.
    Intelligence of children with diabetes mellitus. Pediatrics 1961; 28: 764–770.
    OpenUrlPubMedWeb of Science
  15. 15.↵
    1. Mauras N,
    2. Buckingham B,
    3. White NH,
    4. Tsalikian E,
    5. Weinzimer SA,
    6. Jo B, et al.
    Impact of type 1 diabetes in the developing brain in children: A longitudinal study. Diabetes Care 2021; 44: 983–992.
    OpenUrlAbstract/FREE Full Text
  16. 16.
    1. Abo-El-Asrar M,
    2. Andrawes NG,
    3. Rabie MA,
    4. El-Gabry DA,
    5. Khalifa AG,
    6. El-Sherif M, et al.
    Cognitive functions in children and adolescents with early-onset diabetes mellitus in Egypt. Appl Neuropsychol Child 2018; 7: 21–30.
    OpenUrl
  17. 17.↵
    1. Ghetti S,
    2. Kuppermann N,
    3. Rewers A,
    4. Myers SR,
    5. Schunk JE,
    6. Stoner MJ, et al.
    Cognitive function following diabetic ketoacidosis in children with new-onset or previously diagnosed type 1 diabetes. Diabetes Care 2020; 43: 2768–2775.
    OpenUrlAbstract/FREE Full Text
  18. 18.↵
    1. Patiño-Fernández AM,
    2. Delamater AM,
    3. Applegate EB,
    4. Brady E,
    5. Eidson M,
    6. Nemery R, et al.
    Neurocognitive functioning in preschool-age children with type 1 diabetes mellitus. Pediatric diabetes 2010; 11: 424–430.
    OpenUrlCrossRefPubMed
  19. 19.↵
    1. Tonoli C,
    2. Heyman E,
    3. Roelands B,
    4. Pattyn N,
    5. Buyse L,
    6. Piacentini MF, et al.
    Type 1 diabetes-associated cognitive decline: A meta-analysis and update of the current literature. J Diabetes 2014; 6: 499–513.
    OpenUrlCrossRefPubMed
  20. 20.↵
    1. Naguib JM,
    2. Kulinskaya E,
    3. Lomax CL,
    4. Garralda ME.
    Neuro-cognitive performance in children with type 1 diabetes--a meta-analysis. J Pediatr Psychol 2009; 34: 271–282.
    OpenUrlCrossRefPubMedWeb of Science
  21. 21.↵
    1. Strudwick SK,
    2. Carne C,
    3. Gardiner J,
    4. Foster JK,
    5. Davis EA,
    6. Jones TW.
    Cognitive functioning in children with early onset type 1 diabetes and severe hypoglycemia. J Pediatr 2005; 147: 680–685.
    OpenUrlCrossRefPubMedWeb of Science
  22. 22.↵
    1. Ghetti S,
    2. Kuppermann N,
    3. Rewers A,
    4. Myers SR,
    5. Schunk JE,
    6. Stoner MJ, et al.
    Cognitive function following diabetic ketoacidosis in young children with type 1 diabetes. Endocrinol Diabetes Metab 2023; 6: e412.
    OpenUrl
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