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In BriefIn this issue
Open Access

In this issueSystematic ReviewOriginal ArticlesCase Report

Saudi Medical Journal October 2023, 44 (10) 949;
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Systematic Review

Overview of hypertension in Saudi Arabia. A systematic review and meta-analysis

Alshammari et al assess the prevalence, awareness, treatment, and control of hypertension of 29 studies with 278,873 individuals aged 14 to 100 years old in Saudi Arabia between 1990-2022. e prevalence of hypertension was high, with low awareness, treatment, and control rates among Saudis. Therefore, policymakers and healthcare providers must work harmoniously to promote health and to prevent, detect, and control hypertension early.

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Prisma ow chart summarizes the search’ screening and selection of the reviewed hypertensive articles.

see page 951

Original Articles

Physiological association of the breakpoint with the duration of hyperventilation

Sadiqa et al observe the relationship between body mass index and breath-holding time (BHT) as well as that between BHT and duration of hyperventilation (DOH) in young healthy adults aged 18-22 years. Physically healthy students of both genders were included. A total of 110 healthy subjects, of whom 9 were excluded because of technically incorrect spirometric manoeuvres. Therefore, for the data analysis, there were 101 healthy participants. A strong association was observed between BHT and DOH in all subjects in men and in women. Moreover, a nonsignificant weak inverse linear regression was found between the BMI and BHT of all subjects (β= −0.087, p=0.38), of men (β= −0.241, p=0.11), and of women (β= −0.092, p=0.49). No association was found between BMI and BHT. A strong positive association was observed between BHT and DOH in all healthy young people.

see page 995

Negative pressure wound therapy (NPWT) is superior to conventional moist dressings in wound bed preparation for diabetic foot ulcers-a randomized controlled trial

Wu et al compare the efficacy of negative pressure wound therapy (NPWT) and alginate dressings on wound bed preparation prior to split thickness skin graft (STSG) surgery, as well as to investigate the underlying mechanisms. Patients in the NPWT group had less time to STSG surgery than the control group. The patients in the NPWT group had prominently increased survival rates of skin graft, increased wound blood perfusion, and decreased NET formation in comparison with the control group. Negative pressure wound therapy is superior to conventional moist dressings in wound bed preparation prior to STSG surgery for patients with chronic DFUs.

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A Kaplan‒Meier plot and histological analysis.

see page 1020

Case Report

Macrophage activation syndrome induced by Staphylococcus Epidermidis in a pediatric patient with cystic fibrosis and familial Mediterranean fever

Polat et al present an 8-year-old girl with girl with cystic fibrosis (CF) and familial Mediterranean fever who developed macrophage activation syndrome (MAS) after contracting a Staphylococcus epidermidis infection. There was no accompanying abdominal pain, chest pain, or joint complaints. Staphylococcus epidermidis infections and autoinflammatory diseases may lead to the development of MAS in pediatric CF patients.

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Therapeutic intervention and laboratory parameters.

see page 1061

  • Copyright: © Saudi Medical Journal

This is an Open Access journal and articles published are distributed under the terms of the Creative Commons Attribution-NonCommercial License (CC BY-NC). Readers may copy, distribute, and display the work for non-commercial purposes with the proper citation of the original work.

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Saudi Medical Journal: 44 (10)
Saudi Medical Journal
Vol. 44, Issue 10
1 Oct 2023
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© 2025 Saudi Medical Journal Saudi Medical Journal is copyright under the Berne Convention and the International Copyright Convention.  Saudi Medical Journal is an Open Access journal and articles published are distributed under the terms of the Creative Commons Attribution-NonCommercial License (CC BY-NC). Readers may copy, distribute, and display the work for non-commercial purposes with the proper citation of the original work. Electronic ISSN 1658-3175. Print ISSN 0379-5284.

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