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Review ArticleReview Article
Open Access

Understanding the prevalence, progression, and management of metabolic syndrome in Saudi Arabia

Faez Falah Alshehri
Saudi Medical Journal October 2023, 44 (10) 973-986; DOI: https://doi.org/10.15537/smj.2023.44.10.20230450
Faez Falah Alshehri
From the Department of Clinical Laboratory Sciences, College of Applied Medical Sciences, Shaqra University, Shaqra, Kingdom of Saudi Arabia.
PhD
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    Figure 1

    - Overview of metabolic syndrome.

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    Figure 2

    - Epidemiology of metabolic syndrome in Saudi Arabia.

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    Figure 3

    - Mechanisms resulting in the clinical signs of metabolic syndrome.

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    Table 1

    - Accessible natural metabolic syndrome remedies.

    OriginCompoundMechanismReferences
    Date palm (Phoenix dactylifera L.)Carotenoids and phenolicsAnti-hyperglycemic, antioxidant and anti-inflammatory, inhibited lipid peroxidation, cardioprotective effect86,88–90,92,93
    Olive oil (Oleaeuropaea L.)Oleuropein, hydroxytyrosol and tyrosolInhibit lipid and cholesterol breakdown, control obesity, possess oxidative action68,69,71
    Honey (Apismellifera)Flavonoids, phenolic acids, and phenolic acid derivativesAnti-obesity effects, reduce cardiovascular risk factors, decline in blood glucose levels96,98,137
    Sorghum (Sorghum bicolor L.)Phenolic compounds, 3-deoxyanthocyanidins 3-DXA & tanninsAnti-hyperglycemic, prevent CVD, anti-cancer and anti-inflammatory, control obesity99–102
    Barley (Hordeumvulgare)Whole Grain (Fiber/Vitamin B)Improve digestion and appetite, control obesity, blood triglycerides, anti-hyperglycemic119,120
    Turmeric (Curcuma longa)CurcuminAnti-inflammatory and antioxidant, prevent cancer, reduce heart disease risk, control obesity, anti-hyperglycemic103–105
    Garlic (Allium sativum)GarlicinAnti-hyperglycemic, antioxidative and anti-platelet, total cholesterol and triglyceride, anti-inflammatory properties128–130
    Cinnamon (Cinnamomumverum)Inner bark (peel)- polyphenols and flavonoidsAnti-hyperglycemic, anti-inflammatory properties, anti-thrombotic, lipid-lowering properties, anti-cancer effects, control BP106,107
    Barberry/Rhizomacoptidis (Berberis vulgaris)BerberineAnti-hyperglycemic and anti-bacterial, prevent CVD, control lipoproteins and triglycerides levels, control systolic BP, lowering cholesterol level138–140
    Green tea (Camellia sinensis)Catechins, L-theanine, and caffeineAnti-diabetic and antioxidant, degrade lipoproteins, prevent CVD, anti-obesity and effective on MetS81–83
    Fish (Atlantic mackerel, Atlantic Salmon), Rice (Oryza sativa), Flaxseed (Linumusitatissimum)Omega-3 fatty acid (Docosahexaenoic acid [DHA])Effective on MetS, anti-inflammatory and antioxidant, prevent CVD, reduce triglycerides, lower BP72–74
    • DXA: deoxyanthocyanidins, CVD: cardio vascular disease, Bp: blood pressure

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Saudi Medical Journal: 44 (10)
Saudi Medical Journal
Vol. 44, Issue 10
1 Oct 2023
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Understanding the prevalence, progression, and management of metabolic syndrome in Saudi Arabia
Faez Falah Alshehri
Saudi Medical Journal Oct 2023, 44 (10) 973-986; DOI: 10.15537/smj.2023.44.10.20230450

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Understanding the prevalence, progression, and management of metabolic syndrome in Saudi Arabia
Faez Falah Alshehri
Saudi Medical Journal Oct 2023, 44 (10) 973-986; DOI: 10.15537/smj.2023.44.10.20230450
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Keywords

  • metabolic syndrome (MetS)
  • hypertension
  • insulin resistance
  • diabetes
  • obesity
  • phytochemicals

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© 2025 Saudi Medical Journal Saudi Medical Journal is copyright under the Berne Convention and the International Copyright Convention.  Saudi Medical Journal is an Open Access journal and articles published are distributed under the terms of the Creative Commons Attribution-NonCommercial License (CC BY-NC). Readers may copy, distribute, and display the work for non-commercial purposes with the proper citation of the original work. Electronic ISSN 1658-3175. Print ISSN 0379-5284.

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