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Research ArticleOriginal Article
Open Access

Prevalence of stroke among patients with chronic kidney disease, Taif, Saudi Arabia

Adnan A. Mubaraki, Waad D. Alotaibi, Afnan K. Sibyani, Ghaida T. Alrbaiai, Haneen S. Almalki, Hashim M. Atallah, Abdullah S. Basfar, Asrar Alqaedi, Hisham A. Althobaiti, Mohammed M. Algethami and Youssef A. Althobaiti
Saudi Medical Journal November 2023, 44 (11) 1139-1144; DOI: https://doi.org/10.15537/smj.2023.44.11.20230206
Adnan A. Mubaraki
From the Department of Medicine (Mubaraki); from the College of Medicine (Atallah, Basfar), Taif University, from the Department of Internal Medicine (Alotaibi), King Abdulaziz Specialist Hospital; from the Department of Medicine (Y. A. Althobaiti), King Abdulaziz Specialist Hospital, from the Department of Nephrology (Alqaedi), Taif Children Hospital, from the Department of Medicine (H. A. Althobaiti), King Faisal Medical Complex, from the Department of Medicine (Algethami), Alhada Armed Forces Hospital, Taif, from the Department of Neurology (Sibyani), National Guard Health Affairs, from the Department of Neurology (Alrbaiai), King Abdullah Medical Complex, Directorate of Health Affairs, Jeddah, and from the Department of Emergency Medicine (Almalki), Riyadh Second Health Cluster, Riyadh, Kingdom of Saudi Arabia.
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Waad D. Alotaibi
From the Department of Medicine (Mubaraki); from the College of Medicine (Atallah, Basfar), Taif University, from the Department of Internal Medicine (Alotaibi), King Abdulaziz Specialist Hospital; from the Department of Medicine (Y. A. Althobaiti), King Abdulaziz Specialist Hospital, from the Department of Nephrology (Alqaedi), Taif Children Hospital, from the Department of Medicine (H. A. Althobaiti), King Faisal Medical Complex, from the Department of Medicine (Algethami), Alhada Armed Forces Hospital, Taif, from the Department of Neurology (Sibyani), National Guard Health Affairs, from the Department of Neurology (Alrbaiai), King Abdullah Medical Complex, Directorate of Health Affairs, Jeddah, and from the Department of Emergency Medicine (Almalki), Riyadh Second Health Cluster, Riyadh, Kingdom of Saudi Arabia.
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  • ORCID record for Waad D. Alotaibi
  • For correspondence: [email protected]
Afnan K. Sibyani
From the Department of Medicine (Mubaraki); from the College of Medicine (Atallah, Basfar), Taif University, from the Department of Internal Medicine (Alotaibi), King Abdulaziz Specialist Hospital; from the Department of Medicine (Y. A. Althobaiti), King Abdulaziz Specialist Hospital, from the Department of Nephrology (Alqaedi), Taif Children Hospital, from the Department of Medicine (H. A. Althobaiti), King Faisal Medical Complex, from the Department of Medicine (Algethami), Alhada Armed Forces Hospital, Taif, from the Department of Neurology (Sibyani), National Guard Health Affairs, from the Department of Neurology (Alrbaiai), King Abdullah Medical Complex, Directorate of Health Affairs, Jeddah, and from the Department of Emergency Medicine (Almalki), Riyadh Second Health Cluster, Riyadh, Kingdom of Saudi Arabia.
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Ghaida T. Alrbaiai
From the Department of Medicine (Mubaraki); from the College of Medicine (Atallah, Basfar), Taif University, from the Department of Internal Medicine (Alotaibi), King Abdulaziz Specialist Hospital; from the Department of Medicine (Y. A. Althobaiti), King Abdulaziz Specialist Hospital, from the Department of Nephrology (Alqaedi), Taif Children Hospital, from the Department of Medicine (H. A. Althobaiti), King Faisal Medical Complex, from the Department of Medicine (Algethami), Alhada Armed Forces Hospital, Taif, from the Department of Neurology (Sibyani), National Guard Health Affairs, from the Department of Neurology (Alrbaiai), King Abdullah Medical Complex, Directorate of Health Affairs, Jeddah, and from the Department of Emergency Medicine (Almalki), Riyadh Second Health Cluster, Riyadh, Kingdom of Saudi Arabia.
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Haneen S. Almalki
From the Department of Medicine (Mubaraki); from the College of Medicine (Atallah, Basfar), Taif University, from the Department of Internal Medicine (Alotaibi), King Abdulaziz Specialist Hospital; from the Department of Medicine (Y. A. Althobaiti), King Abdulaziz Specialist Hospital, from the Department of Nephrology (Alqaedi), Taif Children Hospital, from the Department of Medicine (H. A. Althobaiti), King Faisal Medical Complex, from the Department of Medicine (Algethami), Alhada Armed Forces Hospital, Taif, from the Department of Neurology (Sibyani), National Guard Health Affairs, from the Department of Neurology (Alrbaiai), King Abdullah Medical Complex, Directorate of Health Affairs, Jeddah, and from the Department of Emergency Medicine (Almalki), Riyadh Second Health Cluster, Riyadh, Kingdom of Saudi Arabia.
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Hashim M. Atallah
From the Department of Medicine (Mubaraki); from the College of Medicine (Atallah, Basfar), Taif University, from the Department of Internal Medicine (Alotaibi), King Abdulaziz Specialist Hospital; from the Department of Medicine (Y. A. Althobaiti), King Abdulaziz Specialist Hospital, from the Department of Nephrology (Alqaedi), Taif Children Hospital, from the Department of Medicine (H. A. Althobaiti), King Faisal Medical Complex, from the Department of Medicine (Algethami), Alhada Armed Forces Hospital, Taif, from the Department of Neurology (Sibyani), National Guard Health Affairs, from the Department of Neurology (Alrbaiai), King Abdullah Medical Complex, Directorate of Health Affairs, Jeddah, and from the Department of Emergency Medicine (Almalki), Riyadh Second Health Cluster, Riyadh, Kingdom of Saudi Arabia.
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Abdullah S. Basfar
From the Department of Medicine (Mubaraki); from the College of Medicine (Atallah, Basfar), Taif University, from the Department of Internal Medicine (Alotaibi), King Abdulaziz Specialist Hospital; from the Department of Medicine (Y. A. Althobaiti), King Abdulaziz Specialist Hospital, from the Department of Nephrology (Alqaedi), Taif Children Hospital, from the Department of Medicine (H. A. Althobaiti), King Faisal Medical Complex, from the Department of Medicine (Algethami), Alhada Armed Forces Hospital, Taif, from the Department of Neurology (Sibyani), National Guard Health Affairs, from the Department of Neurology (Alrbaiai), King Abdullah Medical Complex, Directorate of Health Affairs, Jeddah, and from the Department of Emergency Medicine (Almalki), Riyadh Second Health Cluster, Riyadh, Kingdom of Saudi Arabia.
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Asrar Alqaedi
From the Department of Medicine (Mubaraki); from the College of Medicine (Atallah, Basfar), Taif University, from the Department of Internal Medicine (Alotaibi), King Abdulaziz Specialist Hospital; from the Department of Medicine (Y. A. Althobaiti), King Abdulaziz Specialist Hospital, from the Department of Nephrology (Alqaedi), Taif Children Hospital, from the Department of Medicine (H. A. Althobaiti), King Faisal Medical Complex, from the Department of Medicine (Algethami), Alhada Armed Forces Hospital, Taif, from the Department of Neurology (Sibyani), National Guard Health Affairs, from the Department of Neurology (Alrbaiai), King Abdullah Medical Complex, Directorate of Health Affairs, Jeddah, and from the Department of Emergency Medicine (Almalki), Riyadh Second Health Cluster, Riyadh, Kingdom of Saudi Arabia.
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Hisham A. Althobaiti
From the Department of Medicine (Mubaraki); from the College of Medicine (Atallah, Basfar), Taif University, from the Department of Internal Medicine (Alotaibi), King Abdulaziz Specialist Hospital; from the Department of Medicine (Y. A. Althobaiti), King Abdulaziz Specialist Hospital, from the Department of Nephrology (Alqaedi), Taif Children Hospital, from the Department of Medicine (H. A. Althobaiti), King Faisal Medical Complex, from the Department of Medicine (Algethami), Alhada Armed Forces Hospital, Taif, from the Department of Neurology (Sibyani), National Guard Health Affairs, from the Department of Neurology (Alrbaiai), King Abdullah Medical Complex, Directorate of Health Affairs, Jeddah, and from the Department of Emergency Medicine (Almalki), Riyadh Second Health Cluster, Riyadh, Kingdom of Saudi Arabia.
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Mohammed M. Algethami
From the Department of Medicine (Mubaraki); from the College of Medicine (Atallah, Basfar), Taif University, from the Department of Internal Medicine (Alotaibi), King Abdulaziz Specialist Hospital; from the Department of Medicine (Y. A. Althobaiti), King Abdulaziz Specialist Hospital, from the Department of Nephrology (Alqaedi), Taif Children Hospital, from the Department of Medicine (H. A. Althobaiti), King Faisal Medical Complex, from the Department of Medicine (Algethami), Alhada Armed Forces Hospital, Taif, from the Department of Neurology (Sibyani), National Guard Health Affairs, from the Department of Neurology (Alrbaiai), King Abdullah Medical Complex, Directorate of Health Affairs, Jeddah, and from the Department of Emergency Medicine (Almalki), Riyadh Second Health Cluster, Riyadh, Kingdom of Saudi Arabia.
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Youssef A. Althobaiti
From the Department of Medicine (Mubaraki); from the College of Medicine (Atallah, Basfar), Taif University, from the Department of Internal Medicine (Alotaibi), King Abdulaziz Specialist Hospital; from the Department of Medicine (Y. A. Althobaiti), King Abdulaziz Specialist Hospital, from the Department of Nephrology (Alqaedi), Taif Children Hospital, from the Department of Medicine (H. A. Althobaiti), King Faisal Medical Complex, from the Department of Medicine (Algethami), Alhada Armed Forces Hospital, Taif, from the Department of Neurology (Sibyani), National Guard Health Affairs, from the Department of Neurology (Alrbaiai), King Abdullah Medical Complex, Directorate of Health Affairs, Jeddah, and from the Department of Emergency Medicine (Almalki), Riyadh Second Health Cluster, Riyadh, Kingdom of Saudi Arabia.
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  • Article
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Article Figures & Data

Tables

    • View popup
    Table 1

    - Sociodemographic details.

    Variablesn (%)
    Hospital’s name
    Al-Hada964 (51.9)
    King Abdulaziz328 (17.7)
    King Faisal457 (24.6)
    Prince Mansour108 (5.8)
    Age (years)
    ≤25101 (5.4)
    26-35127 (6.8)
    36-45168 (9.0)
    46-55232 (12.5)
    >551229 (66.2)
    Gender
    Female756 (40.7)
    Male1101 (59.3)
    Marital status
    Single169 (9.1)
    Married935 (50.4)
    Divorced or widowed40 (2.2)
    Not recorded713 (38.4)
    Educational qualification
    Primary school or illiterate118 (6.3)
    Secondary (high school)42 (2.3)
    Collage and above68 (3.7)
    Not recorded1629 (87.7)
    Body mass index
    Underweight56 (3.0)
    Normal226 (12.2)
    Overweight251 (13.5)
    Obese361 (19.4)
    Not recorded963 (51.9)

    Values are precented as numbers and precentages (%).

      • View popup
      Table 2

      - Clinical characteristics related to chronic kidney disease.

      Characteristicsn (%)P-values
      Type of CKD
      CKD847 (45.6) 
      ESRD1010 (54.4) 
      GFR
      CKD  
      Mildly to moderately decreased11 (1.3) 
      Moderately to severely decreased20 (2.4) 
      Severely decreased816 (96.3)<0.001
      ESRD  
      Moderately to severely decreased1 (0.1) 
      Severely decreased1009 (99.9) 
      Dialysis
      CKD  
      No804 (94.9) 
      Yes43 (5.1) 
      ESRD <0.001
      No142 (14.1) 
      Yes868 (85.9) 
      Type of dialysis (n=911)
      CKD  
      Hemodialysis38 (88.4) 
      Peritoneal dialysis5 (11.6) 
      ESRD <0.001
      Hemodialysis756 (87.1) 
      Peritoneal dialysis112 (12.9) 
      Duration of dialysis (n=911)
      CKD  
      <1 years18 (41.9) 
      1-2 years11 (25.6) 
      3-5 years10 (23.3) 
      6-10 years4 (9.3) 
      ESRD <0.001
      <1 years359 (41.4) 
      1-2 years264 (30.4) 
      3-5 years182 (21.0) 
      6-10 years55 (6.3) 
      >10 years8 (0.9) 

      Values are presented as numbers and precentages (%).

      CKD: chronic kidney disease, GFR: glomerular filtration rate, ESRD: end stage renal disease

        • View popup
        Table 3

        - Prevalence of stroke and its characteristics.

        Characteristicsn (%)
        Diagnosed with stroke154 (8.3)
        Duration of onset kidney disease (n=154)
        <1 year75 (48.7)
        1-2 years36 (23.4)
        3-5 years19 (12.3)
        6-10 years12 (7.8)
        >10 years12 (7.8)
        Stroke (n=154)
        Hemorrhagic stroke29 (18.8)
        Ischemic stroke125 (81.2)

        Values are presented as numbers and precentages (%).

          • View popup
          Table 4

          - Relationship of stroke with chronic kidney disease and dialysis.

          VariablesStrokeP-values
          NoYesTotal
          Stages of CKD
          0105 (89.7)12 (10.3)117 (100)0.238
          157 (89.1)7 (10.9)64 (100)
          2200 (90.5)21 (9.5)221 (100)
          3291 (94.2)18 (5.8)309 (100)
          496 (96.0)4 (4.0)100 (100)
          5922 (91.3)88 (8.7)1010 (100)
          Duration of dialysis
          <1 years1212 (91.8)108 (8.2)1320 (100)0.769
          1-2 years257 (92.8)20 (7.2)277 (100)
          3-5 years174 (90.6)18 (9.4)192 (100)
          6-10 years52 (88.1)7 (11.9)59 (100)
          >10 years8 (88.9)1 (11.1)9 (100)
          Type of dialysis
          Hemodialysis725 (91.0)72 (9.0)797 (100)0.315
          Peritoneal dialysis978 (92.3)82 (7.7)1060 (100)

          Vlaues are presented as numbers and precentages (%). CKD: chronic kidney disease

            • View popup
            Table 5

            - Relationship between type of stroke and dialysis.

            VariablesType strokeP-values
            HemorrhagicIschemicTotal
            Duration of dialysis
            <1 years1166 (88.3)154 (11.7)1320 (100)0.234
            1-2 years257 (92.8)20 (7.2)277 (100)
            3-5 years175 (91.1)17 (8.9)192 (100)
            6-10 years52 (88.1)7 (11.9)59 (100)
            >10 years8 (88.9)1 (11.1)9 (100)
            Type of dialysis
            Hemodialysis726 (91.1)71 (8.9)797 (100)0.029
            Peritoneal dialysis932 (87.9)128 (12.1)1060 (100)

            Values are presented as numbers and precentages (%).

              • View popup
              Table 6

              - Multivariate logistic regression model (independent variable = stroke).

              VariablesOR95% CIP-values
              LowerUpper
              Age above 55 years3.301.865.86<0.001
              Gender0.760.521.120.166
              Marital status (married)1.270.822.600.001
              Education level0.240.041.340.103
              BMI of >250.900.781.040.152
              Hypertension3.111.586.120.001
              Diabetes0.830.571.210.331
              Acute kidney injury2.300.717.410.163
              Benign prostatic hyperplasia1.350.613.000.466
              Chronic obstructive pulmonary disease1.960.794.850.148
              Hyperlipidemia3.180.3330.870.318
              Ischemic heart disease1.380.952.000.043
              Urinary tract infection1.150.423.170.786
              Hypothyroidism1.320.742.370.346
              On dialysis0.990.641.550.975
              On dialysis for >5 years1.130.891.440.327
              Constant0.09  0.001

              OR: odds ratio, CI: confidence interval, BMI: body mass index

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              1 Nov 2023
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              Prevalence of stroke among patients with chronic kidney disease, Taif, Saudi Arabia
              Adnan A. Mubaraki, Waad D. Alotaibi, Afnan K. Sibyani, Ghaida T. Alrbaiai, Haneen S. Almalki, Hashim M. Atallah, Abdullah S. Basfar, Asrar Alqaedi, Hisham A. Althobaiti, Mohammed M. Algethami, Youssef A. Althobaiti
              Saudi Medical Journal Nov 2023, 44 (11) 1139-1144; DOI: 10.15537/smj.2023.44.11.20230206

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              Prevalence of stroke among patients with chronic kidney disease, Taif, Saudi Arabia
              Adnan A. Mubaraki, Waad D. Alotaibi, Afnan K. Sibyani, Ghaida T. Alrbaiai, Haneen S. Almalki, Hashim M. Atallah, Abdullah S. Basfar, Asrar Alqaedi, Hisham A. Althobaiti, Mohammed M. Algethami, Youssef A. Althobaiti
              Saudi Medical Journal Nov 2023, 44 (11) 1139-1144; DOI: 10.15537/smj.2023.44.11.20230206
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              Keywords

              • prevalence
              • chronic kidney disease
              • renal failure
              • end-stage renal disease
              • glomerular filtration
              • cerebrovascular disease
              • stroke

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