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Research ArticleOriginal Article
Open Access

Isotretinoin-induced epistaxis among acne vulgaris patients

A cross sectional study from Saudi Arabia

Hanan Ibrahim Almuzaini, Ali Saeed Alamri and Razan Ibrahim Almuzaini
Saudi Medical Journal December 2024, 45 (12) 1347-1354; DOI: https://doi.org/10.15537/smj.2024.45.12.20240791
Hanan Ibrahim Almuzaini
From the General and Specialized Surgery Department (Almuzaini), Head and Neck Surgery, College of Medicine, Taibah University, Al Madina Al Munawwarah; from the Department of Dermatology and Venereology (Alamri), Security Forces Hospital; and from Alhaya Medical Company (Almuzaini), Riyadh, Kingdom of Saudi Arabia.
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Ali Saeed Alamri
From the General and Specialized Surgery Department (Almuzaini), Head and Neck Surgery, College of Medicine, Taibah University, Al Madina Al Munawwarah; from the Department of Dermatology and Venereology (Alamri), Security Forces Hospital; and from Alhaya Medical Company (Almuzaini), Riyadh, Kingdom of Saudi Arabia.
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Razan Ibrahim Almuzaini
From the General and Specialized Surgery Department (Almuzaini), Head and Neck Surgery, College of Medicine, Taibah University, Al Madina Al Munawwarah; from the Department of Dermatology and Venereology (Alamri), Security Forces Hospital; and from Alhaya Medical Company (Almuzaini), Riyadh, Kingdom of Saudi Arabia.
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References

  1. 1.↵
    1. Tan JK,
    2. Bhate K
    . A global perspective on the epidemiology of acne. Br J Dermatol 2015; 172: 3–12.
    OpenUrlCrossRefPubMed
  2. 2.↵
    1. Makrantonaki E,
    2. Ganceviciene R,
    3. Zouboulis C
    . An update on the role of the sebaceous gland in the pathogenesis of acne. Dermatoendocrinol 2011; 3: 41–49.
    OpenUrlCrossRefPubMed
  3. 3.↵
    1. Alghamdi WA,
    2. Alwesaibie HS,
    3. Albesher MA,
    4. Alghamdi FK,
    5. Albaqshi AA
    . Knowledge, attitude, and practice regarding the use of isotretinoin in Saudi Arabia. Cureus 2023; 15: e50516.
    OpenUrlPubMed
  4. 4.↵
    1. Pile HD,
    2. Sadiq NM
    . Isotretinoin. In: StatPearls. Treasure Island (FL): StatPearls Publishing; 2024 Jan-.
  5. 5.
    1. Hoag JB,
    2. Terry P,
    3. Mitchell S,
    4. Reh D,
    5. Merlo CA
    . An epistaxis severity score for hereditary hemorrhagic telangiectasia. Laryngoscope 2010; 120: 838–843.
    OpenUrlCrossRefPubMed
  6. 6.↵
    1. Chang J,
    2. Nock MR,
    3. Cohen JM,
    4. Bunick CG
    . Acne accounts for an almost 2.5-fold higher proportion of dermatology visits among adult females compared to adult males in the United States: A study of the national ambulatory medical care survey from 2002-2016. PLoS One 2023; 18: e0290763.
    OpenUrlPubMed
  7. 7.↵
    1. Bakheet KMA,
    2. Alghanemi RG,
    3. Alsiyoufi AM,
    4. Abduljabbar M,
    5. Hariri J
    . Females’ Knowledge and Use of Isotretinoin (Roaccutane) in the Western Region of Saudi Arabia. Cureus. 2020; 12: e12148.
    OpenUrlPubMed
  8. 8.↵
    1. Brzezinski P,
    2. Borowska K,
    3. Chiriac A,
    4. Smigielski J
    . Adverse effects of isotretinoin: A large, retrospective review. Dermatol Ther 2017; 30.
  9. 9.↵
    1. Gorpelioglu C,
    2. Ozol D,
    3. Sarifakioglu E
    . Influence of isotretinoin on nasal mucociliary clearance and lung function in patients with acne vulgaris. Int J Dermatol 2010; 49: 87–90.
    OpenUrlPubMed
  10. 10.↵
    1. Blasiak RC,
    2. Stamey CR,
    3. Burkhart CN,
    4. Lugo-Somolinos A,
    5. Morrell DS
    . High-dose isotretinoin treatment and the rate of retrial, relapse, and adverse effects in patients with acne vulgaris. JAMA Dermatol 2013; 149: 1392–1398.
    OpenUrlPubMed
  11. 11.↵
    1. Ertam I,
    2. Babur Y,
    3. Unal I,
    4. Alper S
    . The frequency of skin diseases among students in a university clinic. Skinmed 2010; 8: 261–263.
    OpenUrlPubMed
  12. 12.↵
    1. Tasli H,
    2. Yurekli A,
    3. Gokgoz MC,
    4. Karakoc O
    . Effects of oral isotretinoin therapy on the nasal cavities. Braz J Otorhinolaryngol 2020; 86: 99–104.
    OpenUrlPubMed
  13. 13.↵
    1. Alzoubi KH,
    2. Khabour OF,
    3. Hassan RE,
    4. Qarqaz F,
    5. Al-Azzam S,
    6. Mhaidat N
    . The effect of genetic polymorphisms of RARA gene on the adverse effects profile of isotretinoin-treated acne patients. Int J Clin Pharmacol Ther 2013; 51: 631–640.
    OpenUrlPubMed
  14. 14.↵
    1. Quoc A Nguyen
    . Epistaxis – An Overview. https://emedicine.medscape.com/article/863220-overview#a1
  15. 15.↵
    1. Abrich V,
    2. Brozek A,
    3. Boyle TR,
    4. Chyou PH,
    5. Yale SH
    . Risk factors for recurrent spontaneous epistaxis. Mayo Clin Proc 2014; 89: 1636–643.
    OpenUrlCrossRefPubMed
  16. 16.
    1. Cingoz F,
    2. Oz BS,
    3. Arslan G,
    4. Guler A,
    5. Sahin MA,
    6. Gunay C, et al.
    Is chronic obstructive pulmonary disease a risk factor for epistaxis after coronary artery bypass graft surgery? Cardiovasc J Afr 2014; 25: 279–281.
    OpenUrlPubMed
  17. 17.↵
    1. Purkey MR,
    2. Seeskin Z,
    3. Chandra R
    . Seasonal variation and predictors of epistaxis. Laryngoscope 2014; 124: 2028–2033.
    OpenUrlCrossRefPubMed
  18. 18.↵
    1. Tunkel DE,
    2. Anne S,
    3. Payne SC,
    4. Ishman SL,
    5. Rosenfeld RM,
    6. Abramson PJ, et al.
    Clinical practice guideline: nosebleed (epistaxis). Otolaryngol Head Neck Surg 2020; 162: S1–S38.
    OpenUrlCrossRefPubMed
  19. 19.↵
    1. Younis NS,
    2. Al-Harbi NY
    . Public understanding and awareness of isotretinoin use and safety in Al Ahsa, Eastern Saudi Arabia. Ther Innov Regul Sci 2019; 53: 618–622.
    OpenUrlPubMed
  20. 20.↵
    1. İşlek A,
    2. Yıldız MG
    . Evaluation of Nasal Mucociliary Clearance, Nasal Obstruction Symptom Evaluation, and Epistaxis Severity Score in Isotretinoin Treatment. Ear Nose Throat J 2021; 100: 566–569.
    OpenUrlPubMed
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Saudi Medical Journal: 45 (12)
Saudi Medical Journal
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1 Dec 2024
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Isotretinoin-induced epistaxis among acne vulgaris patients
Hanan Ibrahim Almuzaini, Ali Saeed Alamri, Razan Ibrahim Almuzaini
Saudi Medical Journal Dec 2024, 45 (12) 1347-1354; DOI: 10.15537/smj.2024.45.12.20240791

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Isotretinoin-induced epistaxis among acne vulgaris patients
Hanan Ibrahim Almuzaini, Ali Saeed Alamri, Razan Ibrahim Almuzaini
Saudi Medical Journal Dec 2024, 45 (12) 1347-1354; DOI: 10.15537/smj.2024.45.12.20240791
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Keywords

  • Isotretinoin
  • epistaxis
  • acne vulgaris
  • nasal obstruction
  • nasal dryness
  • Saudi Arabia

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