Article Figures & Data
Tables
Factors No
(n= 307,90.8%)Yes
(n=31, 9.2%)Gender n
(Mean)%
(SD)n
(Mean)%
(SD)P-value Female 251 81.7 23 75 0.357 Male 56 18.3 8 25 Height 1.6 0.1 1.6 0.1 0.897 Weight 81.4 20.0 76 13.8 0.141 Body mass index 31.5 7.1 29.6 6.2 0.15 Age 44.2 11.6 42.8 11.7 0.535 No Yes Factors n
(Mean)%
(SD)n
(Mean)%
(SD)P-value Bethesda classification 0.003** 1 1 0.4 2 7.1 2 101 35.8 2 7.1 3 80 28.4 7 25 4 26 9.2 0 0 5 25 8.9 4 14.3 6 49 17.4 13 46.4 Type of pathology 0.003** Classical 246 80.4 28 87.5 Follicular 34 11.1 1 3.1 Hurthle cell variant 2 0.7 1 3.1 Oncocytic 6 2 2 6.3 Tall cell 18 5.9 0 0 Thyroiditis 130 43.9 16 55.2 0.245 Multifocality Multifoci 103 33.7 13 40.6 0.430 Single focus 203 66.3 19 59.4 Goitrous thyroid 197 70.4 12 48 0.055 ETE 28 10 18 58.1 <0.001** ECE 27 12.7 10 43.5 <0.001** Margin 52 18.1 10 31.3 0.094 LVI 3 1.2 9 29 <0.001** Perineural invasion 3 2.2 1 4.5 0.450 Recurrence in the thyroid bed 15 5.5 1 3.4 0.640 Recurrence in the lymph nodes 3 1 1 3.1 0.332 Residual and received RAI 23 7.7 11 34.4 <0.001** Residual needed completion surgery 5 1.7 2 6.3 0.099 Preoperative TSH level 2.2 2.2 2.6 2.2 0.1 FT4 15.4 11.1 13.7 2.8 0.1 FT3 5.1 4.6 5.5 4.4 0.1 Tumor size (largest in cm) 0.5 0.4 0.7 0.3 0.2 ETE: extrathyroidal extension, ECE: extracapsular extension, LVI: lymphovascular invasion, RAI: radio-active iodine, TSH: thyroid stimulating hormone,
↵** Significant at p<0.05
Univariate Multivariate Factors 95% CI 95% CI OR Lower Upper P-value OR Lower Upper P-value Female 1 Male 1.5 0.6 3.5 0.36 Height 1.3 0.0 79.286 0.897 Weight 1 1 1.005 0.141 Body mass index 1 0.9 1.015 0.15 Age 1 1 1.022 0.534 Bethesda class 1 1 - - - Bethesda class 2 0.0 0.0 0.159 0.001** Bethesda class 3 0.0 0.0 0.545 0.015** Bethesda class 4 - - . 0.998 Bethesda class 5 0.1 0.0 1.1 0.059 Bethesda class 6 0.1 0.0 1.579 0.11 Pathology: classical 1 - - - Pathology: follicular 0.3 0.0 1.961 0.191 Pathology: Hurthle cell variant 4.4 0.4 50.002 0.233 Pathology: oncocytic 2.9 0.6 15.209 0.201 Pathology: tall cell - - - 0.998 Thyroiditis 1.6 0.7 3.384 0.248 Multifocal 1.3 0.6 2.838 0.431 Single focus 1 - - - Goitrous thyroid 0.4 0.2 0.852 0.019** 0.151 0.039 0.584 0.006** ETE 12.4 5.5 27.993 <0.001** 7.724 1.859 32.102 0.005** ECE 5.3 2.1 13.269 <0.001** 5.897 1.3 26.748 0.021** Margin 1.9 1.0 3.486 0.036** LVI 33.5 8.5 133.009 <0.001** 25.817 2.461 270.806 0.007** Perineural invasion 2.1 0.2 21.575 0.518 Recurrence in the thyroid bed 0.6 0.1 4.827 0.643 Recurrence in lymph nodes 3.2 0.3 31.956 0.317 Residual and received RAI 6.3 2.7 14.625 <0.001** Residual needed completion surgery 3.8 0.7 20.224 0.123 Preoperative TSH level 1.1 0.9 1.230 0.352 FT4 0.9 0.8 1.06 0.221 FT3 1 0.9 1.1286 0.766 Tumor size (largest in cm) 1.8 0.9 3.859 0.109 LNM: lymph node metastasis, ETE: extrathyroidal extension, ECE: extracapsular extension, LVI: lymphovascular Invasion, RAI: radio-active iodine, TSH: thyroid stimulating hormone, CI: confidence interval, OR: odds ratio,
↵** Significantly at p<0.05.
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