Article Figures & Data
Figures
- Figure 1
- Histopathological and immunohistochemical features of pancreatic diffuse large b-cell lymphoma. A) Section of pancreatic neoplasm tumor showing diffuse infiltration of large lymphoid cells with areas of necrosis (Hematoxylin and eosin, 200×). B) Higher power of the same case reveals large lymphoma cell infiltration (Hematoxylin and eosin, 400×). C) large lymphoid cells expressing CD20 (Immunohistochemistry stain, 200×). D: large lymphoid cells are negative for CD3 (Immunohistochemistry stain, 200×). E) High proliferation index by Ki-67, approximately 90% of tumor cells expressing KI-67 (Immunohistochemistry stain, 200×). F: large lymphoid cells expressing CD10 (Immunohistochemistry stain, 200×).
Tables
- Table 1
- Summary of the primary pancreatic lymphoma cases from 2 referral hospitals in the Western regions of Saudi Arabia.
Age/gender Site in pancreas Procedure Clinical Radiology Diagnosis Treatment Follow-up 1 37/F head EUS-needle core Abdominal and back pain, nausea, weight loss Solid mass (10x7.5 cm DLBCL R-CHOP Died after 6 months 2 52/M head Excisional biopsy after frozen section Abdominal pain, weight loss Solid mass (5x4.5 cm DLBCL R-CHOP Died after 14 months 3 57/F head EUS-needle core Abdominal pain, jaundice Solid mass involving the whole pancreas (6x5.3 cm) Follicular lymphoma, Grade 1 Not available Not available 4 47/M head CT guided Core biopsy Abdominal pain, nausea, vomiting, weight loss, fever, night sweats Solid mass (8.6x6.5 cm DLBCL R-CHOP 3 months. Lost follow up 5 36/M head CT guided Core biopsy HIV +, Abdominal pain, jaundice, nausea, vomiting, weight loss. Solid mass involving the whole pancreas (9.6x8 cm) DLBCL R-CHOP disease progression, sepsis, CMV viremia and died 5 months after diagnosis 6 71/M Tail CT guided Core biopsy Abdominal pain, nausea, weight loss. Solid mass involving tail of the pancreas (9x6.1 cm) High-grade b cell lymphoma R-CHOP 2 months follow up 7 60/F Tail Distal pancreatectomy resection fever, weight loss, nausea, night sweat Distal pancreas and splenomegaly (4.2x 3.1cm) MALT Surgical resection and splenectomy 16 months follow up 8 61/ M head CT guided Core biopsy Abdominal pain, loss of weight Solid mass (4.5x4 cm) DLBCL R-CHOP 23 months follow up EUS: Endoscopic ultrasound, CT: Computed tomography, DLBCL: diffuse large b-cell lymphoma, MALT: Mucosa-associated lymphoid tissue, R-CHOP: rituximab, cyclophosphamide, doxorubicin hydrochloride, vincristine sulfate, and prednisone, CMV: Cytomegalovirus
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