Research ArticleOriginal Article
Open Access

Clinical presentation and outcomes of patients with rhabdomyolysis

A tertiary care center experience

Mohammed Tawhari, Abdulaziz Aldalaan, Rahaf Alanazi, Sarah Aldharman, Turki Alnafisah, Nawaf Alawad, Abdullah M. Alhejji, Abdulrahman Yousef Alhabeeb and Moustafa S. Alhamadh
Saudi Medical Journal May 2024, 45 (5) 510-517; DOI: https://doi.org/10.15537/smj.2024.45.5.20230560

References

  1. 1.↵
    1. Stanley M,
    2. Chippa V,
    3. Aeddula NR,
    4. Quintanilla Rodriguez BS,
    5. Adigun R. Rhabdomyolysis
    . In: StatPearls. Treasure Island (FL): StatPearls Publishing; 2024 Jan. 2023 Apr 16.
  2. 2.↵
    1. Gupta A,
    2. Thorson P,
    3. Penmatsa KR,
    4. Gupta P.
    Rhabdomyolysis: revisited. Ulster Med J 2021; 90: 61–69.
    OpenUrl
  3. 3.↵
    1. Chavez LO,
    2. Leon M,
    3. Einav S,
    4. Varon J.
    Beyond muscle destruction: a systematic review of rhabdomyolysis for clinical practice. Crit Care 2016; 20: 135.
    OpenUrlCrossRefPubMed
  4. 4.↵
    1. Al-Homrany M.
    Epidemiology of acute renal failure in hospitalized patients: experience from southern Saudi Arabia. East Mediterr Health J 2003; 9: 1061–1067.
    OpenUrlPubMed
  5. 5.↵
    1. Stahl K,
    2. Rastelli E,
    3. Schoser B.
    A systematic review on the definition of rhabdomyolysis. J Neurol 2020; 267: 877–882.
    OpenUrlPubMed
  6. 6.↵
    1. Lagandré S,
    2. Arnalsteen L,
    3. Vallet B,
    4. Robin E,
    5. Jany T,
    6. Onraed B, et al.
    Predictive factors for rhabdomyolysis after bariatric surgery. Obes Surg 2006; 16: 1365–1370.
    OpenUrlCrossRefPubMedWeb of Science
  7. 7.↵
    1. Linares LA,
    2. Golomb BA,
    3. Jaojoco JA,
    4. Sikand H,
    5. Phillips PS.
    The modern spectrum of rhabdomyolysis: drug toxicity revealed by creatine kinase screening. Curr Drug Saf 2009; 4: 181–187.
    OpenUrlCrossRefPubMed
  8. 8.↵
    1. Sauret JM,
    2. Marinides G,
    3. Wang GK. Rhabdomyolysis
    . Am Fam Physician 2002; 65: 907–912.
    OpenUrlPubMedWeb of Science
  9. 9.↵
    1. Nance JR,
    2. Mammen AL.
    Diagnostic evaluation of rhabdomyolysis. Muscle Nerve 2015; 51: 793–810.
    OpenUrlCrossRefPubMed
  10. 10.
    1. Oshima Y.
    Characteristics of drug-associated rhabdomyolysis: analysis of 8,610 cases reported to the U.S. Food and Drug Administration. Intern Med 2011; 50: 845–853.
    OpenUrlCrossRefPubMed
  11. 11.
    1. Pariser JJ,
    2. Pearce SM,
    3. Patel SG,
    4. Anderson BB,
    5. Packiam VT,
    6. Shalhav AL, et al.
    Rhabdomyolysis after major urologic surgery: epidemiology, risk factors, and outcomes. Urology 2015; 85:1328–1332.
    OpenUrl
  12. 12.↵
    1. Grunau BE,
    2. Pourvali R,
    3. Wiens MO,
    4. Levin A,
    5. Li J,
    6. Grafstein E, et al.
    Characteristics and thirty-day outcomes of emergency department patients with elevated creatine kinase. Acad Emerg Med 2014; 21: 631–636.
    OpenUrl
  13. 13.↵
    1. Scalco RS,
    2. Gardiner AR,
    3. Pitceathly RD,
    4. Zanoteli E,
    5. Becker J,
    6. Holton JL, et al.
    Rhabdomyolysis: a genetic perspective. Orphanet J Rare Dis 2015; 10: 51.
    OpenUrlCrossRef
  14. 14.↵
    1. Waldman W,
    2. Kabata PM,
    3. Dines AM,
    4. Wood DM,
    5. Yates C,
    6. Heyerdahl F, et al
    ; Euro-DEN Research Group. Rhabdomyolysis related to acute recreational drug toxicity-A Euro-DEN study. PLoS One 2021; 16: e0246297.
    OpenUrlPubMed
  15. 15.↵
    1. Yang J,
    2. Zhou J,
    3. Wang X,
    4. Wang S,
    5. Tang Y,
    6. Yang L.
    Risk factors for severe acute kidney injury among patients with rhabdomyolysis. BMC Nephrol 2020; 21: 498.
    OpenUrl
  16. 16.
    1. Graham DJ,
    2. Staffa JA,
    3. Shatin D,
    4. Andrade SE,
    5. Schech SD,
    6. La Grenade L, et al.
    Incidence of hospitalized rhabdomyolysis in patients treated with lipid-lowering drugs. JAMA 2004; 292: 2585–2590.
    OpenUrlCrossRefPubMedWeb of Science
  17. 17.↵
    1. Kunakorntham P,
    2. Pattanaprateep O,
    3. Dejthevaporn C,
    4. Thammasudjarit R,
    5. Thakkinstian A.
    Detection of statin-induced rhabdomyolysis and muscular related adverse events through data mining technique. BMC Med Inform Decis Mak 2022; 22: 233.
    OpenUrl
  18. 18.↵
    Prevalence and correlates of dyslipidemia among adults in Saudi Arabia: results from a national survey. Al-Kaabba AF, Al-Hamdan NA, El Tahir A, Abdalla AM, Saeed AA, Hamza MA. Open J Endocr Metab Dis 2012; 2: 89–97.
    OpenUrl
  19. 19.↵
    1. Larbi EB.
    Drug-induced rhabdomyolysis. Ann Saudi Med 1998; 18: 525–530.
    OpenUrlPubMedWeb of Science
  20. 20.↵
    1. Gheshlaghi F.
    Malignant drug-induced rhabdomyolysis. J Nephropathol 2012; 1: 59–60.
    OpenUrl
  21. 21.↵
    1. Saquib N,
    2. Rajab AM,
    3. Saquib J,
    4. AlMazrou A.
    Substance use disorders in Saudi Arabia: a scoping review. Subst Abuse Treat Prev Policy 2020; 15: 41.
    OpenUrlPubMed
  22. 22.↵
    1. Melli G,
    2. Chaudhry V,
    3. Cornblath DR.
    Rhabdomyolysis: an evaluation of 475 hospitalized patients. Medicine (Baltimore) 2005; 84: 377–385.
    OpenUrlCrossRefPubMedWeb of Science
  23. 23.↵
    1. Lau Hing Yim C,
    2. Wong EW,
    3. Jellie LJ,
    4. Lim AK.
    Illicit drug use and acute kidney injury in patients admitted to hospital with rhabdomyolysis. Intern Med J 2019; 49: 1285–1292.
    OpenUrl
  24. 24.↵
    1. Herráez García J,
    2. Torracchi Carrasco AM,
    3. Antolí-Royo AC,
    4. de la Fuente Blanco R,
    5. Santos Jiménez MT. Rabdomiólisis
    . Estudio descriptivo de 449 pacientes [Rhabdomyolysis. A descriptive study of 449 patients]. Med Clin (Barc) 2012; 139: 238–242.
    OpenUrlPubMed
  25. 25.↵
    1. Daniele DO,
    2. Murray J.
    Update: exertional rhabdomyolysis, active component, U.S. Armed Forces, 2017-2021. MSMR. 2022; 29: 15–20.
    OpenUrl
  26. 26.↵
    1. Alpers JP,
    2. Jones LK Jr.
    Natural history of exertional rhabdomyolysis: a population-based analysis. Muscle Nerve P2010; 42: 487–491.
  27. 27.↵
    1. Ghaznawi HI,
    2. Ibrahim MA.
    Heat stroke and heat exhaustion in pilgrims performing the Haj (annual pilgrimage) in Saudi Arabia. Ann Saudi Med 1987; 7: 323–326.
    OpenUrl
  28. 28.↵
    1. Luetmer MT,
    2. Boettcher BJ,
    3. Franco JM,
    4. Reisner JH,
    5. Cheville AL,
    6. Finnoff JT.
    Exertional Rhabdomyolysis: A Retrospective Population-based Study. Med Sci Sports Exerc 2020; 52: 608–615.
    OpenUrlPubMed
  29. 29.↵
    1. El-Abdellati E,
    2. Eyselbergs M,
    3. Sirimsi H,
    4. Hoof VV,
    5. Wouters K,
    6. Verbrugghe W, et al.
    An observational study on rhabdomyolysis in the intensive care unit. Exploring its risk factors and main complication: acute kidney injury. Ann Intensive Care. 2013; 3: 8.
    OpenUrlCrossRefPubMed
  30. 30.↵
    1. Bosch X,
    2. Poch E,
    3. Grau JM.
    Rhabdomyolysis and acute kidney injury [Erratum in: N Engl J Med. 2011; 364: 20. N Engl J Med 2009; 361: 62–72.
    OpenUrlCrossRefPubMedWeb of Science
  31. 31.↵
    1. Boutaud O,
    2. Roberts LJ 2nd.
    Mechanism-based therapeutic approaches to rhabdomyolysis-induced renal failure. Free Radic Biol Med 2011; 51: 1062–1067.
    OpenUrlCrossRefPubMed
  32. 32.↵
    1. Rodríguez E,
    2. Soler MJ,
    3. Rap O,
    4. Barrios C,
    5. Orfila MA,
    6. Pascual J.
    Risk factors for acute kidney injury in severe rhabdomyolysis. PLoS One 2013; 8: e82992.
    OpenUrlCrossRefPubMed
  33. 33.↵
    1. Morandi L,
    2. Angelini C,
    3. Prelle A,
    4. Pini A,
    5. Grassi B,
    6. Bernardi G, et al.
    High plasma creatine kinase: review of the literature and proposal for a diagnostic algorithm. Neurol Sci 2006; 27: 303–311.
    OpenUrlPubMed
  34. 34.↵
    1. Akmal M,
    2. Massry SG.
    Reversible hepatic dysfunction associated with rhabdomyolysis. Am J Nephrol 1990; 10: 49–52.
    OpenUrlPubMedWeb of Science
Back to top

In this issue

Print
Download PDF
Email Article
Citation Tools
Bookmark this article

Jump to section

Keywords