Skip to main content

Main menu

  • Home
  • Content
    • Latest
    • Archive
    • home
  • Info for
    • Authors
    • Reviewers
    • Subscribers
    • Institutions
    • Advertisers
    • Join SMJ
  • About Us
    • About Us
    • Editorial Office
    • Editorial Board
  • More
    • Advertising
    • Alerts
    • Feedback
    • Folders
    • Help
  • Other Publications
    • NeuroSciences Journal

User menu

  • My alerts
  • Log in

Search

  • Advanced search
Saudi Medical Journal
  • Other Publications
    • NeuroSciences Journal
  • My alerts
  • Log in
Saudi Medical Journal

Advanced Search

  • Home
  • Content
    • Latest
    • Archive
    • home
  • Info for
    • Authors
    • Reviewers
    • Subscribers
    • Institutions
    • Advertisers
    • Join SMJ
  • About Us
    • About Us
    • Editorial Office
    • Editorial Board
  • More
    • Advertising
    • Alerts
    • Feedback
    • Folders
    • Help
  • Follow psmmc on Twitter
  • Visit psmmc on Facebook
  • RSS
Research ArticleOriginal Article
Open Access

Serum levels of zinc, folate, and vitamin B12 in healthy children aged 3-12 months

Is routine screening necessary?

Furkan Kalayci and Metin Yigit
Saudi Medical Journal August 2024, 45 (8) 821-825; DOI: https://doi.org/10.15537/smj.2024.45.8.20240248
Furkan Kalayci
From the Department of Pediatrics, Ankara Bilkent City Hospital, Ankara, Turkey.
MD
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Furkan Kalayci
  • For correspondence: [email protected]
Metin Yigit
From the Department of Pediatrics, Ankara Bilkent City Hospital, Ankara, Turkey.
MD
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • Article
  • Figures & Data
  • eLetters
  • Info & Metrics
  • References
  • PDF
Loading

References

  1. 1.↵
    1. Carreiro AL,
    2. Dhillon J,
    3. Gordon S,
    4. Higgins KA,
    5. Jacobs AG,
    6. McArthur BM, et al.
    The macronutrients, appetite, and energy intake. Annu Rev Nutr 2016; 36: 73-103.
    OpenUrlPubMed
  2. 2.↵
    1. Shergill-Bonner R
    . Micronutrients. Paediatr Child Health 2017; 27: 357-362.
    OpenUrl
  3. 3.↵
    1. Dong C,
    2. Ge P,
    3. Ren X,
    4. Zhao X,
    5. Wang J,
    6. Fan H, et al.
    The micronutrient status of children aged 24-60 months living in rural disaster areas one year after the Wenchuan Earthquake. PLoS One 2014; 9: e88444.
    OpenUrl
  4. 4.↵
    WHO. Nutrient adequacy of exclusive breastfeeding for the term infant during the first 6 months of life. [Updated 2002; accessed 2024 Feb 12] Available from: https://www.who.int/publications/i/item/9241562110
  5. 5.↵
    1. Raffaeli G,
    2. Manzoni F,
    3. Cortesi V,
    4. Cavallaro G,
    5. Mosca F,
    6. Ghirardello S
    . Iron homeostasis disruption and oxidative stress in preterm newborns. Nutrients 2020; 12: 1554.
    OpenUrl
  6. 6.↵
    1. Saggese G,
    2. Vierucci F,
    3. Prodam F,
    4. Cardinale F,
    5. Cetin I,
    6. Chiappini E, et al.
    Vitamin D in pediatric age: consensus of the Italian Pediatric Society and the Italian Society of Preventive and Social Pediatrics, jointly with the Italian Federation of Pediatricians. Ital J Pediatr 2018; 44: 51.
    OpenUrl
  7. 7.↵
    1. Bronsky J,
    2. Campoy C,
    3. Braegger C
    . ESPGHAN/ESPEN/ESPR/CSPEN guidelines on pediatric parenteral nutrition: vitamins. Clin Nutr 2018; 37: 2366-2378.
    OpenUrl
  8. 8.↵
    1. Behere RV,
    2. Deshmukh AS,
    3. Otiv S,
    4. Gupte MD,
    5. Yajnik CS
    . Maternal vitamin B12 status during pregnancy and its association with outcomes of pregnancy and health of the offspring: a systematic review and implications for policy in India. Front Endocrinol (Lausanne) 2021; 12: 619176.
    OpenUrl
  9. 9.↵
    1. Akcaboy M,
    2. Malbora B,
    3. Zorlu P,
    4. Altınel E,
    5. Oguz MM,
    6. Senel S
    . Vitamin B12 deficiency in infants. Indian J Pediatr 2015; 82: 619-624.
    OpenUrlCrossRefPubMed
  10. 10.↵
    1. Mamme NY,
    2. Roba HS,
    3. Fite MB,
    4. Asefa G,
    5. Abrahim J,
    6. Yuya M, et al.
    Serum folate deficiency and associated factors among pregnant women in Haramaya District, Eastern Ethiopia: a community-based study. BMJ Open 2023; 13: e068076.
    OpenUrlAbstract/FREE Full Text
  11. 11.↵
    1. Villagomez A,
    2. Ramtekkar U
    . Iron, magnesium, vitamin D, and zinc deficiencies in children presenting with symptoms of attention-deficit/hyperactivity disorder. Children (Basel) 2014; 1: 261-279.
    OpenUrl
  12. 12.↵
    WHO. Serum and red blood cell folate concentrations for assessing folate status in populations. [Updated 2014; accessed 2024 Feb 12]. Available from: https://www.who.int/publications/i/item/WHO-NMH-NHD-EPG-15.01
  13. 13.↵
    1. Harrington DJ
    . Laboratory assessment of vitamin B12 status. J Clin Pathol 2017; 70: 168-173.
    OpenUrlAbstract/FREE Full Text
  14. 14.↵
    1. Tuerk MJ,
    2. Fazel N
    . Zinc deficiency. Curr Opin Gastroenterol 2009; 25: 136-143.
    OpenUrlCrossRefPubMedWeb of Science
  15. 15.
    1. Finamore A,
    2. Massimi M,
    3. Conti Devirgiliis L,
    4. Mengheri E
    . Zinc deficiency induces membrane barrier damage and increases neutrophil transmigration in Caco-2 cells. J Nutr 2008; 138: 1664-1670.
    OpenUrlAbstract/FREE Full Text
  16. 16.↵
    1. Levenson CW,
    2. Morris D
    . Zinc and neurogenesis: making new neurons from development to adulthood. Adv Nutr 2011; 2: 96-100.
    OpenUrlAbstract/FREE Full Text
  17. 17.↵
    1. Tam E,
    2. Keats EC,
    3. Rind F,
    4. Das JK,
    5. Bhutta AZA
    . Micronutrient supplementation and fortification interventions on health and development outcomes among children under-5 in low- and middle-income countries: a systematic review and meta-analysis. Nutrients 2020; 12: 289.
    OpenUrl
  18. 18.↵
    International Zinc Nutrition Consultative Group. Quantifying the risk of zinc deficiency: recommended indicators. [Updated 2007; accessed 2024 Feb 14]. Available from: https://static1.squarespace.com/static/56424f6ce4b0552eb7fdc4e8/t/57493db901dbae66390e9dca/1464417728860/English_brief1.pdf
  19. 19.↵
    1. Wong E,
    2. Molina-Cruz R,
    3. Rose C,
    4. Bailey L,
    5. Kauwell GPA,
    6. Rosenthal J
    . Prevalence and disparities in folate and vitamin B12 deficiency among preschool children in Guatemala. Matern Child Health J 2022; 26: 156-167.
    OpenUrl
  20. 20.↵
    1. Maciej S,
    2. Becker FG,
    3. Cleary M,
    4. Team RM,
    5. Holtermann H,
    6. The D, et al.
    Evaluation of unbound folate levels in breast milk. J of Tur Clin Bio 2020; 18: 343-354.
    OpenUrl
  21. 21.↵
    1. Wolffenbuttel BHR,
    2. Wouters HJCM,
    3. Heiner-Fokkema MR,
    4. van der Klauw MM
    . The many faces of cobalamin (vitamin B12) deficiency. Mayo Clin Proc Innov Qual Outcomes 2019; 3: 200-214.
    OpenUrlCrossRefPubMed
  22. 22.↵
    1. Karagol C,
    2. Yigit M
    . Evaluation of clinical and laboratory findings and diagnostic difficulties in children with vitamin B12 deficiency. Pediatr Pract Res 2022; 10: 6-10.
    OpenUrl
  23. 23.↵
    1. Keikha M,
    2. Shayan-Moghadam R,
    3. Bahreynian M,
    4. Kelishadi R
    . Nutritional supplements and mother’s milk composition: a systematic review of interventional studies. Int Breastfeed J 2021; 16: 1.
    OpenUrl
  24. 24.↵
    1. Kadiyala A,
    2. Palani A,
    3. Rajendraprasath S,
    4. Venkatramanan P
    . Prevalence of vitamin B12 deficiency among exclusively breast fed term infants in South India. J Trop Pediatr 2021; 67: fmaa114.
  25. 25.↵
    1. Azad C,
    2. Jat KR,
    3. Kaur J,
    4. Guglani V,
    5. Palta A,
    6. Tiwari A, et al.
    Vitamin B12 status and neurodevelopmental delay in Indian infants: a hospital-based cross-sectional study. Paediatr Int Child Health 2020; 40: 78-84.
    OpenUrl
  26. 26.↵
    1. Kohli-Kumar M
    . Screening for anemia in children: AAP recommendations--a critique. Pediatrics 2001; 108: E56.
    OpenUrlCrossRefPubMed
  27. 27.↵
    Republic of Turkey Ministry of Health. Infant, child and adolescent follow-up protocols. [Updated 2018; accessed 2024 Feb 28] Available from: https://ekutuphane.saglik.gov.tr/Ekutuphane/kitaplar/Bebek_Cocuk_Ergen_Izlem_Protokolleri_2018.pdf
PreviousNext
Back to top

In this issue

Saudi Medical Journal: 45 (8)
Saudi Medical Journal
Vol. 45, Issue 8
1 Aug 2024
  • Table of Contents
  • Cover (PDF)
  • Index by author
Print
Download PDF
Email Article

Thank you for your interest in spreading the word on Saudi Medical Journal.

NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.

Enter multiple addresses on separate lines or separate them with commas.
Serum levels of zinc, folate, and vitamin B12 in healthy children aged 3-12 months
(Your Name) has sent you a message from Saudi Medical Journal
(Your Name) thought you would like to see the Saudi Medical Journal web site.
Citation Tools
Serum levels of zinc, folate, and vitamin B12 in healthy children aged 3-12 months
Furkan Kalayci, Metin Yigit
Saudi Medical Journal Aug 2024, 45 (8) 821-825; DOI: 10.15537/smj.2024.45.8.20240248

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
Share
Serum levels of zinc, folate, and vitamin B12 in healthy children aged 3-12 months
Furkan Kalayci, Metin Yigit
Saudi Medical Journal Aug 2024, 45 (8) 821-825; DOI: 10.15537/smj.2024.45.8.20240248
Twitter logo Facebook logo Mendeley logo
  • Tweet Widget
  • Facebook Like
  • Google Plus One
Bookmark this article

Jump to section

  • Article
    • Abstract
    • Methods
    • Results
    • Discussion
    • Acknowledgment
    • Footnotes
    • References
  • Figures & Data
  • eLetters
  • References
  • Info & Metrics
  • PDF

Related Articles

  • No related articles found.
  • PubMed
  • Google Scholar

Cited By...

  • No citing articles found.
  • Google Scholar

More in this TOC Section

  • Hematological parameters in recent and past dengue infections in Jazan Province, Saudi Arabia
  • Longitudinal analysis of foodborne disease outbreaks in Saudi Arabia
  • Psychological stress and its association with bronchial asthma in Saudi Arabia
Show more Original Article

Similar Articles

Keywords

  • zinc
  • folate
  • vitamin B12
  • infant
  • micronutrient

CONTENT

  • home

JOURNAL

  • home

AUTHORS

  • home
Saudi Medical Journal

© 2025 Saudi Medical Journal Saudi Medical Journal is copyright under the Berne Convention and the International Copyright Convention.  Saudi Medical Journal is an Open Access journal and articles published are distributed under the terms of the Creative Commons Attribution-NonCommercial License (CC BY-NC). Readers may copy, distribute, and display the work for non-commercial purposes with the proper citation of the original work. Electronic ISSN 1658-3175. Print ISSN 0379-5284.

Powered by HighWire