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Research ArticleOriginal Article
Open Access

Predictors of hypoglycemia among children admitted in the Emergency Pediatric Unit of the University of Maiduguri Teaching Hospital, Maiduguri, Nigeria

Ruqayyatu A. Imam, Hassan A. Elechi, Hauwa Y. Musa, Adamu I. Rabasa and Habiba B. Bakari
Saudi Medical Journal January 2025, 46 (1) 78-85; DOI: https://doi.org/10.15537/smj.2025.46.1.20240679
Ruqayyatu A. Imam
From the Department of Pediatrics (Imam, Musa), University of Maiduguri Teaching Hospital; from the Department of Pediatrics (Elechi, Rabasa), College of Medical Sciences, University of Maiduguri, Maiduguri; and from the Department of Pediatrics (Bakari), College of Medical Sciences, Modibo Adama University, Yola, Nigeria.
MBBS, FWACP
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Hassan A. Elechi
From the Department of Pediatrics (Imam, Musa), University of Maiduguri Teaching Hospital; from the Department of Pediatrics (Elechi, Rabasa), College of Medical Sciences, University of Maiduguri, Maiduguri; and from the Department of Pediatrics (Bakari), College of Medical Sciences, Modibo Adama University, Yola, Nigeria.
MBBS, FWACP
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  • ORCID record for Hassan A. Elechi
  • For correspondence: [email protected]
Hauwa Y. Musa
From the Department of Pediatrics (Imam, Musa), University of Maiduguri Teaching Hospital; from the Department of Pediatrics (Elechi, Rabasa), College of Medical Sciences, University of Maiduguri, Maiduguri; and from the Department of Pediatrics (Bakari), College of Medical Sciences, Modibo Adama University, Yola, Nigeria.
MBBS, FWACP
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Adamu I. Rabasa
From the Department of Pediatrics (Imam, Musa), University of Maiduguri Teaching Hospital; from the Department of Pediatrics (Elechi, Rabasa), College of Medical Sciences, University of Maiduguri, Maiduguri; and from the Department of Pediatrics (Bakari), College of Medical Sciences, Modibo Adama University, Yola, Nigeria.
MBBS, FWACP
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Habiba B. Bakari
From the Department of Pediatrics (Imam, Musa), University of Maiduguri Teaching Hospital; from the Department of Pediatrics (Elechi, Rabasa), College of Medical Sciences, University of Maiduguri, Maiduguri; and from the Department of Pediatrics (Bakari), College of Medical Sciences, Modibo Adama University, Yola, Nigeria.
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Article Figures & Data

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  • Figure 1
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    Figure 1

    - Blood glucose category of the study subjects.

Tables

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    Table 1

    - Association between hypoglycemia and sociodemographic factors, nutritional status, and duration since last meal.

    VariablenHypoglycemiaX2P-value
    Absent n (%)Present n (%)
    Age
    <5 years226190 (84.1)36 (15.9)6.1610.046*
    5-<105844 (75.9)14 (24.1)  
    10-155652 (92.9)4 (7.1)  
    Gender
    Male206179(86.9)27(13.1)3.0140.083
    Female134107 (79.9)27(20.1)  
    Socioeconomic class
    Low222178 (80.2)44 (19.8)7.8990.017^
    Middle9384 (90.3)9 (9.7)  
    High2524 (96.0)1 (4.0)  
    Weight-for-age
    Normal175151 (86.3)24 (13.7)6.5050.039*
    Moderate underweight4945 (91.8)4 (8.2)  
    Severe underweight11690 (77.6)26 (22.4)  
    Height-for-age
    Normal255213 (83.5)42 (16.5)3.9980.136
    Moderate stunting3735 (94.6)2 (5.4)  
    Severe stunting4838 (79.2)10 (19.8)  
    Duration since last meal
    <8 hours (h)127120 (94.5)7 (5.5)72.300.001
    8- <16 h9590 (94.7)5 (5.3)  
    16-24 h9667 (72.0)26 (28.0)  
    >24 h259 (36.0)16 (64.0)  
    • View popup
    Table 2

    - Relationship between clinical features and hypoglycemia.

    Variable Hypoglycemia  
    Clinical featuresnAbsent n (%)Present n (%)X2P-value
    Fever289239 (82.7)50 (17.3)2.9030.888
    Cough160135 (84.4)25 (15.6)0.0150.903
    Difficulty in breathing129103 (79.8)26 (20.2)2.8400.092
    Diarrhoea173138 (79.8)35 (20.2)4.9860.026*
    Vomiting193160 (82.9)33 (17.1)0.4940.482
    Abdominal distention6545 (69.2)20 (30.8)13.3310.001*
    Anorexia244196 (80.3)48 (19.7)9.2900.002*
    Convulsions9265 (70.7)27 (29.3)17.1180.001*
    Weakness196146 (74.5)50 (25.5)32.1090.001*
    Dysuria7061 (87.1)9 (12.9)0.6040.437
    Frequency2826 (92.9)2 (7.1)1.7440.187
    Tachypnea226183 (81.0)43 (19.0)4.9880.026*
    Tachycardia223182 (81.6)41 (18.4)3.0400.081
    Hypertension5140 (78.4)11 (21.6)1.4520.228
    Unarousable coma6228 (45.2)34 (54.8)86.1350.001*
    Oedema2721 (77.8)6 (22.2)0.8820.348
    Dehydration4429 (65.9)15 (34.1)12.5430.001*
    Pallor6052 (86.7)8 (13.3)0.3540.552
    Hepatomegaly1814 (77.8)4 (22.2)0.5720.450
    Dyspnea7462 (83.8)12 (16.2)0.0080.929
    Crepitation6654 (81.8)12 (18.2)0.3240.569
    • View popup
    Table 3

    - Relationship between hypoglycemia and clinical diagnosis.

    DiagnosesnAbsent n (%)Present n (%)X2P-value
    Severe malaria4224 (57.1)18 (42.9)26.0990.001
    Pneumonia5145 (88.2)6 (11.8)0.7610.383
    Diarrheal disease2623 (88.5)3 (11.5)0.3980.597
    Enteric fever1818 (100.0)0 (0.0)3.5890.089
    Meningitis97 (77.8)2 (22.2)0.2780.639
    Febrile convulsion1918 (94.7)1 (5.3)1.6990.226
    SAM5340 (75.5)13 (24.5)3.5130.061
    Surgical cases3024 (80.0)6 (20.0)0.4180.518
    Severe sepsis96 (66.7)3 (33.3)2.1070.158
    Sickle cell crisis2121 (100.0)0 (0.0)4.2260.033
    UTI1515 (100.0)0 (0.0)2.9630.142
    Pharyngotonsilitis1715 (88.2)2 (11.8)0.2270.475
    Others3030 (100.0)0 (0.0)6.2120.007

    UTI: urinary tract infections, SAM: severe acute malnutrition

      • View popup
      Table 4

      - Multiple regression for factors associated with hypoglycemia.

      VariablesTotal enrolledHypoglycemia n=58Odds ratio (95% CI)P-value
      Age
      <5 years22636 (15.9)6.218 (1.077-35.912) 
      5-< 10 year5814 (24.1)5.730 (0.889-34.702)0.041*
      10-15 years564 (7.1)10.057
      Social status
      Low22244 (19.8)3.191 (0.226-44.967) 
      Middle939 (9.7)3.179 (0.198-50.996)0.390
      High251 (4.0)10.414
      Weight-for-age
      Normal17524 (13.7)1 
      Moderate underweight494 (8.2)0.530 (0.100-2.811)0.456
      Severe underweight11626 (22.4)3.692 (1.266-10.971)0.017*
      Duration since last meal
      <8 h1277 (5.1)1 
      8- <16 h955 (5.3)0.668 (0.152-2.945)0.594
      16-24 h9326 (28.3)5.696 (1.768-18.352)0.004*
      >24 h2516 (64.0)30.279(5.569164.633)<0.001*
      Abdominal distensionYes6520 (30.8)2.863 (0.948—8.649)0.062
      no27534 (12.4)1
      AnorexiaYes24448 (19.7)1.096 (0.338-3.560)0.876
      no966 (6.3)1
      Diarrheayes17335 (64.8)1.303 (0.492-3.451)0.594
      no16719 (11.4)1
      ConvulsionsYes9227 (29.3)1.472 (0.505-4.288)0.478
      no24827 (10.7)1
      Weaknessyes19650 (25.5)6.556 (1.730-24.850)0.006*
      no1444 (2.8)1
      Comayes6234 (54.8)9.479 (3.092-29.059)<0.001*
      no27820 (7.2)1
      Dehydrationyes4415 (34.1)0.483 (0.113-2.070)0.327
      no29639(13.2)1
      Tachypneayes22643 (19.0)1.294 (0.469--3.570)0.619
      no11411 (9.6)1
      Severe malariayes4218 (42.9)2.720 (0.554-13.365)0.021*
      no29836 (12.1)1

      Values are presented as number and percentages (%).

      OR: odds ratio, CI: confidence interval h: hours

      • ↵* Significant p-value.

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    Predictors of hypoglycemia among children admitted in the Emergency Pediatric Unit of the University of Maiduguri Teaching Hospital, Maiduguri, Nigeria
    Ruqayyatu A. Imam, Hassan A. Elechi, Hauwa Y. Musa, Adamu I. Rabasa, Habiba B. Bakari
    Saudi Medical Journal Jan 2025, 46 (1) 78-85; DOI: 10.15537/smj.2025.46.1.20240679

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    Predictors of hypoglycemia among children admitted in the Emergency Pediatric Unit of the University of Maiduguri Teaching Hospital, Maiduguri, Nigeria
    Ruqayyatu A. Imam, Hassan A. Elechi, Hauwa Y. Musa, Adamu I. Rabasa, Habiba B. Bakari
    Saudi Medical Journal Jan 2025, 46 (1) 78-85; DOI: 10.15537/smj.2025.46.1.20240679
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