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Systematic ReviewSystematic Review
Open Access

Hypothyroidism is a risk factor for transient ischemic attack

A meta-analysis

Jian Li, Hui Liu and Yan Li
Saudi Medical Journal February 2025, 46 (2) 117-123; DOI: https://doi.org/10.15537/smj.2025.46.2.20240508
Jian Li
From the Department of Neurology, Huantai County People’s Hospital, Shandong, China.
MM
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Hui Liu
From the Department of Neurology, Huantai County People’s Hospital, Shandong, China.
BD
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Yan Li
From the Department of Neurology, Huantai County People’s Hospital, Shandong, China.
MM
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  • ORCID record for Yan Li
  • For correspondence: [email protected]
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    Figure 1

    - Schematic illustration of literature search and screening process.

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    Figure 2

    - Meta-analysis of clinical hypothyroidism and transient ischemic attack. A) Total; B) study type subgroup analysis.12-18

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    Figure 3

    - Meta-analysis of subclinical hypothyroidism and transient ischemic attack.12-18

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    Figure 4

    - Sensitivity analysis. A) All studies; B) hypothyroidism subgroup; and C) subclinical hypothyroidism group.12-18

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    Figure 5

    - Publication bias funnel plot.

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    Table 1

    - Basic characteristics of the included studies.

    AuthorsYearsDesignsCountriesAgeGender (male/female)Sample sizesQuality scores
    HypothyroidismEuthyroidismHypothyroidismEuthyroidismHypothyroidismEuthyroidism
    Drechsler et al142014cohort studyGerman66.4±8.865.3±8.510/6446/335167818
    Karch et al162014cohort studyUK59.857.06472/2843529817/119815349071496329
    Karakurm et al152007cohort studyTurkish67.2±168.4±11109/14053/49103417
    Schultz et al182011cohort studyDenmark69.567.55/26243/306315499
    Rodondi et al172005cohort studyUS74.8±2.774.7±2.9151/1871188/120433823928
    Dorr et al132008cross-sectional studyPomerania64.0061.0129/971010/82922618399
    Benwenga et al122019cross-sectional studyItaly65.6±12.7 14/100 4796
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Saudi Medical Journal: 46 (2)
Saudi Medical Journal
Vol. 46, Issue 2
1 Feb 2025
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Hypothyroidism is a risk factor for transient ischemic attack
Jian Li, Hui Liu, Yan Li
Saudi Medical Journal Feb 2025, 46 (2) 117-123; DOI: 10.15537/smj.2025.46.2.20240508

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Hypothyroidism is a risk factor for transient ischemic attack
Jian Li, Hui Liu, Yan Li
Saudi Medical Journal Feb 2025, 46 (2) 117-123; DOI: 10.15537/smj.2025.46.2.20240508
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Keywords

  • hypothyroidism
  • transient ischemic attack
  • thyroxine
  • thyroid-stimulating hormone
  • meta analysis

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© 2025 Saudi Medical Journal Saudi Medical Journal is copyright under the Berne Convention and the International Copyright Convention.  Saudi Medical Journal is an Open Access journal and articles published are distributed under the terms of the Creative Commons Attribution-NonCommercial License (CC BY-NC). Readers may copy, distribute, and display the work for non-commercial purposes with the proper citation of the original work. Electronic ISSN 1658-3175. Print ISSN 0379-5284.

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