Article Figures & Data
Tables
Specimen types n (%) Biopsies 137 (86.7) Surgical specimens (n=21) Kasai procedure 14 (8.7) Hepatectomy 5 (3.2) Mass resection 1 (0.6) Abscess drainage 1 (0.6) Values are presented as numbers and percentages (%).
Pathological patterns n (%) Cholestatic/bile duct disorders (n=92) Extrahepatic biliary atresia 32 (34.8) Paucity of bile ducts (syndromic and non-syndromic) 20 (21.7) Neonatal hepatitis 10 (10.9) PFIC-1 3 (3.3) PFIC-2 12 (13.0) PFIC-3 5 (5.4) Choledochal cyst 1 (1.1) PSC 3 (3.3) Cholestasis, NOS 6 (6.5) Inflammatory/infectious disorders (n=21) Autoimmune hepatitis 4 (19.0) Abscess 3 (14.3) Infectious (HCV, fungal) 3 (14.3) Cholestatic hepatitis 1 (4.8) CAH, NOS 10 (47.6) Metabolic disorders (n=19) Glycogen storage disorders 6 (31.6) NAFLD 6 (31.6) Cystic fibrosis 2 (10.5) Lysosomal storage diseases 1 (5.3) A1ATD 1 (5.3) Metabolic disorders, NOS 3 (15.8) Neoplastic disorders (n=12) Benign 5 (41.7) Malignant, 1ry 3 (25.0) Malignant, 2ry 4 (33.3) Values are presented as numbers and percentages (%).
PFIC: progressive familial intrahepatic cholestasis,
PSC: primary sclerosing cholangitis, NOS: not otherwise specified,
HCV: hepatitis C virus, CAH: chronic active hepatitis,
NAFLD: non-alcoholic fatty liver disease, A1ATD: alpha-1 antitrypsin deficiency