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Case ReportCase Report
Open Access

Histopathological and immuno-histochemical characteristics of primary renal primitive neuroectodermal tumor

Fadwa J. Altaf, Ibrahim Mansoor and Awatef A. Jamal
Saudi Medical Journal January 2002, 23 (1) 90-92;
Fadwa J. Altaf
Department of Pathology, King AbdulAziz University Hospital, PO Box 80215, Jeddah 21589, Kingdom of Saudi Arabia. Fax. +966 (2) 6952538.
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Ibrahim Mansoor
Department of Pathology, King AbdulAziz University Hospital, PO Box 80215, Jeddah 21589, Kingdom of Saudi Arabia.
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Awatef A. Jamal
Department of Pathology, King AbdulAziz University Hospital, PO Box 80215, Jeddah 21589, Kingdom of Saudi Arabia.
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Abstract

We report a 32-year-old male who presented with huge (17x10.5x5 cm) right kidney with metastasis in the liver and retroperitoneal lymph nodes. Histological, detailed immunohistochemical studies and electron microscopic examinations were performed. Microscopy revealed small to intermediate sized cells with hyperchromatic nuclei, scanty cytoplasm, abundant mitosis with no pseudorossete formation. Immunohistochemical study revealed positive staining of the tumor cells for S100, neurofilaments, neuron specific enolase, vimentin and myoglobin. Primitive neuroectodermal tumors are rare malignant round cell tumors of the kidney. A correct diagnosis can be made on light microscopic features, and by immunohistochemically positive staining for more than one neural marker. This neoplasm should be differentiated from other renal neoplasms composed of small round cells.

  • Copyright: © Saudi Medical Journal

This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Saudi Medical Journal: 23 (1)
Saudi Medical Journal
Vol. 23, Issue 1
1 Jan 2002
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Histopathological and immuno-histochemical characteristics of primary renal primitive neuroectodermal tumor
Fadwa J. Altaf, Ibrahim Mansoor, Awatef A. Jamal
Saudi Medical Journal Jan 2002, 23 (1) 90-92;

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Histopathological and immuno-histochemical characteristics of primary renal primitive neuroectodermal tumor
Fadwa J. Altaf, Ibrahim Mansoor, Awatef A. Jamal
Saudi Medical Journal Jan 2002, 23 (1) 90-92;
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© 2025 Saudi Medical Journal Saudi Medical Journal is copyright under the Berne Convention and the International Copyright Convention.  Saudi Medical Journal is an Open Access journal and articles published are distributed under the terms of the Creative Commons Attribution-NonCommercial License (CC BY-NC). Readers may copy, distribute, and display the work for non-commercial purposes with the proper citation of the original work. Electronic ISSN 1658-3175. Print ISSN 0379-5284.

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