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Case ReportCase Report
Open Access

Malignant eccrine poroma

Mahmoud S. Al-Ahwal, Ali S. Sawan and Sameer K. Zimmo
Saudi Medical Journal May 2005, 26 (5) 859-861;
Mahmoud S. Al-Ahwal
Associate Professor & Consultant Medical Oncologist, Department of Medicine, King Abdul-Aziz University Hospital, PO Box 80215, Jeddah 21589, Kingdom of Saudi Arabia. Tel. + 966 (2) 6408244 / 6408272 / 0556659600. Fax. +966 (2) 640-8315. E-mail: [email protected]
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Ali S. Sawan
Department of Pathology, King Abdul-Aziz University Hospital, Jeddah, Kingdom of Saudi Arabia.
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Sameer K. Zimmo
Department of Medicine, King Abdul-Aziz University Hospital, Jeddah, Kingdom of Saudi Arabia.
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Abstract

Benign eccrine poroma arises from the intraepidermal portion of the eccrine gland duct. Malignant transformation is rare and should be suspected when these lesions present with pain, bleeding or itching. We report a 44-year-old male patient who presented primarily with a lesion diagnostic of benign eccrine poroma of the right foot sole with no clear evidence of malignancy, which was incompletely excised, followed 5 months later by local recurrence, ulceration, occasional bleeding and right inguinal lymphadenopathy. Incomplete excision of the primary tumor as well as excision of a skin lesion on the right knee joint revealed malignant eccrine poroma with aggressive histology, lymphovascular and perineural invasion. Investigations revealed no evidence of distant metastasis. This tumor might be malignant at the first presentation, which was not confirmed histopathologically considering the short duration of only 5 months for malignant transformation. The patient received 3 cycles of Docetaxel Taxotere, Cisplatin combination chemotherapy with partial response. The management of metastatic malignant eccrine poroma is difficult. It has proven resistant to many chemotherapeutic agents and radiotherapy.

  • Copyright: © Saudi Medical Journal

This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Saudi Medical Journal: 26 (5)
Saudi Medical Journal
Vol. 26, Issue 5
1 May 2005
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Malignant eccrine poroma
Mahmoud S. Al-Ahwal, Ali S. Sawan, Sameer K. Zimmo
Saudi Medical Journal May 2005, 26 (5) 859-861;

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Malignant eccrine poroma
Mahmoud S. Al-Ahwal, Ali S. Sawan, Sameer K. Zimmo
Saudi Medical Journal May 2005, 26 (5) 859-861;
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© 2025 Saudi Medical Journal Saudi Medical Journal is copyright under the Berne Convention and the International Copyright Convention.  Saudi Medical Journal is an Open Access journal and articles published are distributed under the terms of the Creative Commons Attribution-NonCommercial License (CC BY-NC). Readers may copy, distribute, and display the work for non-commercial purposes with the proper citation of the original work. Electronic ISSN 1658-3175. Print ISSN 0379-5284.

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