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Case ReportCase Report
Open Access

Congenital varicella-zoster virus infection. A rare case of severe brain and ocular malformations without limb or cutaneous involvement in a newborn after maternal subclinical infection

Yousef A. Al-Katawee, Yousef A. Al-Hasoun, Mohamed N. Taha and Khalid Al-Moslem
Saudi Medical Journal May 2005, 26 (5) 869-871;
Yousef A. Al-Katawee
Consultant in Pediatrics and Neonatology, Department of Neonatology Al-Yamamah Hospital, PO Box 106208, Riyadh 11666, Kingdom of Saudi Arabia. Tel. +966 (1) 4914444 Ext. 1325/1326. Fax. +966 (1) 4914896 E-mail: [email protected]
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Yousef A. Al-Hasoun
Department of Neonatology, Al-Yamamah Hospital, Riyadh, Kingdom of Saudi Arabia.
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Mohamed N. Taha
Department of Neonatology, Al-Yamamah Hospital, Riyadh, Kingdom of Saudi Arabia.
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Khalid Al-Moslem
Department of Neonatology, Al-Yamamah Hospital, Riyadh, Kingdom of Saudi Arabia.
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Abstract

Although congenital varicella-zoster virus VZV infection is rare, it carries serious morbidity and mortality to the fetus and newborn infant. We report a full term female newborn infant, born to a multipara unbooked mother who had VZV subclinical infection during the first trimester of pregnancy. Routine newborn examination showed cystic malformation of the left eye, and absence of the right eye globe. Radiological work up revealed severe brain and eye malformations, serological studies of both mother and baby were positive for VZV. The baby underwent palliative surgery to the eyes, upon discharge, a plan of multidisciplinary team was made for follow up including neurologist, ophthalmologist, pediatrician and social worker. Congenital VZV infection can be severe enough to cause catastrophic fetal anomalies and damage to the vital organs as many of those infants die in infancy.

  • Copyright: © Saudi Medical Journal

This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Saudi Medical Journal: 26 (5)
Saudi Medical Journal
Vol. 26, Issue 5
1 May 2005
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Congenital varicella-zoster virus infection. A rare case of severe brain and ocular malformations without limb or cutaneous involvement in a newborn after maternal subclinical infection
Yousef A. Al-Katawee, Yousef A. Al-Hasoun, Mohamed N. Taha, Khalid Al-Moslem
Saudi Medical Journal May 2005, 26 (5) 869-871;

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Congenital varicella-zoster virus infection. A rare case of severe brain and ocular malformations without limb or cutaneous involvement in a newborn after maternal subclinical infection
Yousef A. Al-Katawee, Yousef A. Al-Hasoun, Mohamed N. Taha, Khalid Al-Moslem
Saudi Medical Journal May 2005, 26 (5) 869-871;
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© 2025 Saudi Medical Journal Saudi Medical Journal is copyright under the Berne Convention and the International Copyright Convention.  Saudi Medical Journal is an Open Access journal and articles published are distributed under the terms of the Creative Commons Attribution-NonCommercial License (CC BY-NC). Readers may copy, distribute, and display the work for non-commercial purposes with the proper citation of the original work. Electronic ISSN 1658-3175. Print ISSN 0379-5284.

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