Yolk sac tumor of the vagina

Abstract

Malignant germ-cell tumors GCT are rare tumors of childhood accounting for less than 3% of pediatric malignancies. Endodermal sinus tumors EST form the most common histologic subtype of malignant GCT. The vagina is an extremely rare site for GCTs. An 8-month-old female was admitted with a short history of vaginal bleeding, and a mass protruding from the vagina. A mass was palpable anteriorly on rectal examination. Computed tomography showed a tumor mass posterior to the bladder. A biopsy revealed a vaginal EST. The serum alpha-fetoprotein was elevated. Vaginohysterectomy was carried out. She was subsequently referred to the oncologist for further management.