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Case ReportCase Report
Open Access

Severe community-acquired infection caused by methicillin-resistant Staphylococcus aureus in Saudi Arabian children.

Elham E. Bukhari and Fawzia E. Al-Otaibi
Saudi Medical Journal December 2009, 30 (12) 1595-1600;
Elham E. Bukhari
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Fawzia E. Al-Otaibi
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Abstract

Community acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) infection has become a major pathogen causing significant infection in children in Saudi Arabia. It has emerged as a frequent cause of skin and soft tissue infections and can be associated with life-threatening complications such as necrotizing pneumonia and sepsis. Between January 2005 and March 2008, 5 (6%) previously healthy children with invasive CA-MRSA infections were identified from 80 children with community-onset MRSA infections. Three children had osteomyelitis, with one patient presenting a fulminant and extensive soft tissue and bone destruction complicated by deep vein thrombosis and pathological fracture. One child had deep-seated infection, and one infant had severe orbital cellulitis and bilateral orbital abscess complicated by subdural empyema. The median age was 4-years (range 3 months to 17 years). Only one patient had a risk factor. Two patients were initially treated with ineffective antimicrobial therapy (beta-lactam). One isolate showed inducible clindamycin resistance. The recovery was uneventful in all patients. This report should increase the awareness of clinicians regarding severe CA-MRSA infections and highlight the challenges encountered in the choice of therapy of serious infections caused by this organism.

  • Copyright: © Saudi Medical Journal

This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Saudi Medical Journal: 30 (12)
Saudi Medical Journal
Vol. 30, Issue 12
1 Dec 2009
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Severe community-acquired infection caused by methicillin-resistant Staphylococcus aureus in Saudi Arabian children.
Elham E. Bukhari, Fawzia E. Al-Otaibi
Saudi Medical Journal Dec 2009, 30 (12) 1595-1600;

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Severe community-acquired infection caused by methicillin-resistant Staphylococcus aureus in Saudi Arabian children.
Elham E. Bukhari, Fawzia E. Al-Otaibi
Saudi Medical Journal Dec 2009, 30 (12) 1595-1600;
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© 2025 Saudi Medical Journal Saudi Medical Journal is copyright under the Berne Convention and the International Copyright Convention.  Saudi Medical Journal is an Open Access journal and articles published are distributed under the terms of the Creative Commons Attribution-NonCommercial License (CC BY-NC). Readers may copy, distribute, and display the work for non-commercial purposes with the proper citation of the original work. Electronic ISSN 1658-3175. Print ISSN 0379-5284.

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