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Research ArticleOriginal Article
Open Access

Central nervous system anomalies diagnosed antenatally and post-delivery management

Haifaa A. Mansouri
Saudi Medical Journal March 2010, 31 (3) 257-261;
Haifaa A. Mansouri
Department of Obstetrics and Gynecology, King Abdulaziz University Hospital, PO Box 80215, Jeddah 21589, Kingdom of Saudi Arabia. Tel. +966 505622291. Fax. +966 (2) 6920262. E-mail: [email protected]
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Abstract

OBJECTIVE: To find out the prevalence of the central nervous system anomalies (CNS) and the outcome after surgical correction of operable defects.

METHODS: This is a retrospective review of all cases diagnosed antenatally with CNS anomalies in the Department of Obstetrics and Gynecology at King Abdulaziz University Hospital (KAUH), Jeddah, Kingdom of Saudi Arabia from January 1997 to March 2005, and their outcome including perinatal deaths and postoperative outcome following surgical correction carried out as treatment or palliative.

RESULTS: Ninety CNS anomalies were diagnosed antenatally, and 86 were confirmed postnatally. Forty-one (47.7%) were neural tube defects (NTDs) (24 were spina bifida associated with hydrocephalus, 3 encephalocele, 14 anencephaly), 36 (41.9%) were hydrocephalus, 4 (4.65%) holoprosencephaly, 3 (3.4%) microcephaly, and 2 (2.32%) with brain cysts. Of the 41 cases that were operated, 6 (14.6%) died, 26 (63.4%) survived with severe neurological sequelae, 6 (14.6%) lost follow-up, and 3 (7.3%) did well for the period of follow-up.

CONCLUSION: The prevalence of CNS anomalies is comparable to worldwide prevalence. The NTDs are important component of these anomalies, and implementation of strategies to decrease the rate of these anomalies would be beneficial to prevent them as they carry a high rate of handicap and suffering, even after surgical correction.

  • Copyright: © Saudi Medical Journal

This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial License (CC BY-NC), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Saudi Medical Journal: 31 (3)
Saudi Medical Journal
Vol. 31, Issue 3
1 Mar 2010
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Central nervous system anomalies diagnosed antenatally and post-delivery management
Haifaa A. Mansouri
Saudi Medical Journal Mar 2010, 31 (3) 257-261;

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Central nervous system anomalies diagnosed antenatally and post-delivery management
Haifaa A. Mansouri
Saudi Medical Journal Mar 2010, 31 (3) 257-261;
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© 2025 Saudi Medical Journal Saudi Medical Journal is copyright under the Berne Convention and the International Copyright Convention.  Saudi Medical Journal is an Open Access journal and articles published are distributed under the terms of the Creative Commons Attribution-NonCommercial License (CC BY-NC). Readers may copy, distribute, and display the work for non-commercial purposes with the proper citation of the original work. Electronic ISSN 1658-3175. Print ISSN 0379-5284.

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