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Research ArticleOriginal Article
Open Access

Evaluation of the effect of Bupivacaine (Marcaine) in reducing early post tonsillectomy pain

Manal A. Bukhari and Abdulmalik S. Al-Saied
Saudi Medical Journal November 2012, 33 (11) 1201-1204;
Manal A. Bukhari
Department of Otolaryngology, King Saud University, King Abdulaziz Hospital, Riyadh, Kingdom of Saudi Arabia.
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Abdulmalik S. Al-Saied
Department of Otolaryngology, King Saud University, King Abdulaziz Hospital, Riyadh, Kingdom of Saudi Arabia.
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Abstract

OBJECTIVE: To evaluate the effectiveness of bupivacaine as topically applied in reducing post tonsillectomy pain within the first 24 hours.

METHODS: This prospective, randomized, placebo-controlled, intra-individual, single-blind study was conducted at the Otolaryngology Department, King Abdulaziz University Hospital, King Saud University, Riyadh, Kingdom of Saudi Arabia from October 2009 until March 2010. Thirty-five patients underwent cold knife tonsillectomy. One tonsillar fossa was packed with gauze soaked in plain 0.25% bupivacaine, while the other tonsillar fossa was packed with gauze soaked in normal saline (the control side). Both gauzes were applied for 5 minutes. The patients' pain was evaluated on each side using the visual analog scale at 2, 4, 6, 12, and 24 hours post-operatively.

RESULTS: The reduction in pain at 2 and 4 hours was statistically insignificant compared with the control side. However, at 6, 12, and 24 hours post operatively, the reduction of pain was statistically significant.

CONCLUSION: Topical application of bupivacaine at a 0.25% concentration appears to a considerable degree of analgesia within the first 24 hours post tonsillectomy.

  • Copyright: © Saudi Medical Journal

This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial License (CC BY-NC), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Saudi Medical Journal: 33 (11)
Saudi Medical Journal
Vol. 33, Issue 11
1 Nov 2012
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Evaluation of the effect of Bupivacaine (Marcaine) in reducing early post tonsillectomy pain
Manal A. Bukhari, Abdulmalik S. Al-Saied
Saudi Medical Journal Nov 2012, 33 (11) 1201-1204;

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Evaluation of the effect of Bupivacaine (Marcaine) in reducing early post tonsillectomy pain
Manal A. Bukhari, Abdulmalik S. Al-Saied
Saudi Medical Journal Nov 2012, 33 (11) 1201-1204;
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© 2025 Saudi Medical Journal Saudi Medical Journal is copyright under the Berne Convention and the International Copyright Convention.  Saudi Medical Journal is an Open Access journal and articles published are distributed under the terms of the Creative Commons Attribution-NonCommercial License (CC BY-NC). Readers may copy, distribute, and display the work for non-commercial purposes with the proper citation of the original work. Electronic ISSN 1658-3175. Print ISSN 0379-5284.

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