Short term effects of periodontal therapy on inflammatory markers in patients with type-2 diabetes

References

1. ↵
   1. Flemmig TF

   (1999) Periodontitis. Ann Periodontol 4:32–38.

   OpenUrlCrossRefPubMed
2. ↵
   1. Lindhe J,
   2. Karring T,
   3. Lang NP

   1. Kinane DF,
   2. Lindhe J

   (2003) in Clinical Periodontology and Implant Dentistry, Chronic Periodontitis, eds Lindhe J, Karring T, Lang NP (Blackwell Munksgaard, Oxford (UK)) Available from: http: //media.johnwiley.com.au/product_data/excerpt/26/EHEP0023/EHEP002326-2.pdf, pp 209–215.
3. ↵
   1. D’Aiuto F,
   2. Nibali L,
   3. Parkar M,
   4. Suvan J,
   5. Tonetti MS

   (2005) Short-term effects of intensive periodontal therapy on serum inflammatory markers and cholesterol. J Dent Res 84:269–273.

   OpenUrlCrossRefPubMedWeb of Science
4. ↵
   (2010) American Diabetes Association. Diagnosis and classification of diabetes mellitus. Diabetes Care 33(Suppl 1):S62–S69.

   OpenUrlFREE Full Text
5. ↵
   1. Manouchehr-Pour M,
   2. Spagnuolo PJ,
   3. Rodman HM,
   4. Bissada NF

   (1981) Comparison of neutrophil chemotactic response in diabetic patients with mild and severe periodontal disease. J Periodontol 52:410–415.

   OpenUrlPubMedWeb of Science
6. 1. McMullen JA,
   2. Van Dyke TE,
   3. Horoszewicz HU,
   4. Genco RJ

   (1981) Neutrophil chemotaxis in individuals with advanced periodontal disease and a genetic predisposition to diabetes mellitus. J Periodontol 52:167–173.

   OpenUrlCrossRefPubMedWeb of Science
7. ↵
   1. Rose LF,
   2. Mealey BL

   1. Mealey B,
   2. Rees T,
   3. Rose LF,
   4. Grossi SG

   (2004) in Periodontics, Systemic factors impacting the periodontium, eds Rose LF, Mealey BL (Mosby, St. Louis (MO)), pp 791–845.
8. ↵
   1. Stewart JE,
   2. Wager KA,
   3. Friedlander AH,
   4. Zadeh HH

   (2001) The effect of periodontal treatment on glycemic control in patients with type 2 diabetes mellitus. J Clin Periodontol 28:306–310.

   OpenUrlCrossRefPubMedWeb of Science
9. ↵
   1. Rodrigues DC,
   2. Taba MJ,
   3. Novaes AB,
   4. Souza SL,
   5. Grisi MF

   (2003) Effect of non-surgical periodontal therapy on glycemic control in patients with type 2 diabetes mellitus. J Periodontol 74:1361–1367.

   OpenUrlCrossRefPubMed
10. 1. Janket SJ,
    2. Wightman A,
    3. Baird AE,
    4. Van Dyke TE,
    5. Jones JA

    (2005) Does periodontal treatment improve glycemic control in diabetic patients? A meta-analysis of intervention studies. J Dent Res 84:1154–1159.

    OpenUrlCrossRefPubMedWeb of Science
11. ↵
    1. Promsudthi A,
    2. Pimapansri S,
    3. Deerochanawong C,
    4. Kanchanavasita W

    (2005) The effect of periodontal therapy on uncontrolled type 2 diabetes mellitus in older subjects. Oral Dis 11:293–298.

    OpenUrlCrossRefPubMed
12. ↵
    1. Kiran M,
    2. Arpak N,
    3. Unsal E,
    4. Erdogan MF

    (2005) The effect of improved periodontal health on metabolic control in type 2 diabetes mellitus. J Clin Periodontol 32:266–272.

    OpenUrlCrossRefPubMedWeb of Science
13. 1. Giblin LJ,
    2. Boyd LD,
    3. Rainchuso L,
    4. Chadbourne D

    (2014) Short-term effects of non-surgical periodontal therapy on clinical measures of impaired glucose tolerance in people with prediabetes and chronic periodontitis. J Dent Hyg 88(Suppl 1):23–30.

    OpenUrlFREE Full Text
14. ↵
    1. Perayil J,
    2. Suresh N,
    3. Fenol A,
    4. Vyloppillil R,
    5. Bhaskar A,
    6. Menon S

    (2014) Comparison of glycated hemoglobin levels in individuals without diabetes and with and without periodontitis before and after non-surgical periodontal therapy. J Periodontol 85:1658–1666.

    OpenUrl
15. ↵
    1. Salvi GE,
    2. Collins JG,
    3. Yalda B,
    4. Arnold RR,
    5. Lang NP,
    6. Offenbacher S

    (1997) Monocytic TNF alpha secretion patterns in IDDM patients with periodontal diseases. J Clin Periodontol 24:8–16.

    OpenUrlCrossRefPubMedWeb of Science
16. ↵
    1. Hotamisligil GS,
    2. Shargill NS,
    3. Spiegelman BM

    (1993) Adipose expression of tumor necrosis factor-alpha: direct role in obesity-linked insulin resistance. Science 259:87–91.

    OpenUrlAbstract/FREE Full Text
17. ↵
    1. Nishimura F,
    2. Iwamoto Y,
    3. Mineshiba J,
    4. Shimizu A,
    5. Soga Y,
    6. Murayama Y

    (2003) Periodontal disease and diabetes mellitus: the role of tumor necrosis factor-alpha in a 2-way relationship. J Periodontol 74:97–102.

    OpenUrlCrossRefPubMedWeb of Science
18. ↵
    1. Shoelson SE,
    2. Lee J,
    3. Goldfine AB

    (2006) Inflammation and insulin resistance. J Clin Invest 116:1793–1801.

    OpenUrlCrossRefPubMedWeb of Science
19. ↵
    1. Gemmell E,
    2. Marshall RI,
    3. Seymour GJ

    (1997) Cytokines and prostaglandins in immune homeostasis and tissue destruction in periodontal disease. Periodontol 2000 14:112–143.

    OpenUrlCrossRefPubMed
20. ↵
    1. Pradeep AR,
    2. Roopa Y,
    3. Swati PP

    (2008) Interleukin-4, a T-helper 2 cell cytokine, is associated with the remission of periodontal disease. J Periodontal Res 43:712–716.

    OpenUrlCrossRefPubMedWeb of Science
21. 1. Bozkurt FY,
    2. Yetkin AZ,
    3. Berker E,
    4. Tepe E,
    5. Akkus S

    (2006) Anti-inflammatory cytokines in gingival crevicular fluid in patients with periodontitis and rheumatoid arthritis: a preliminary report. Cytokine 35:180–185.

    OpenUrlCrossRefPubMed
22. ↵
    1. Giannopoulou C,
    2. Kamma JJ,
    3. Mombelli A

    (2003) Effect of inflammation, smoking and stress on gingival crevicular fluid cytokine level. J Clin Periodontol 30:145–153.

    OpenUrlCrossRefPubMedWeb of Science
23. ↵
    1. Marcaccini AM,
    2. Meschiari CA,
    3. Sorgi CA,
    4. Saraiva MC,
    5. de Souza AM,
    6. Faccioli LH,
    7. et al.

    (2009) Circulating interleukin-6 and high-sensitivity C-reactive protein decrease after periodontal therapy in otherwise healthy subjects. J Periodontol 80:594–602.

    OpenUrlCrossRefPubMed
24. ↵
    1. Ebersole JL,
    2. Cappelli D

    (2000) Acute-phase reactants in infections and inflammatory diseases. Periodontol 2000 23:19–49.

    OpenUrlCrossRefPubMedWeb of Science
25. ↵
    1. Engebretson S,
    2. Kocher T

    (2013) Evidence that periodontal treatment improves diabetes outcomes: a systematic review and meta-analysis. J Clin Periodontol 40(Suppl 14):153–163.

    OpenUrlCrossRef
26. ↵
    1. Page RC,
    2. Eke PI

    (2007) Case definitions for use in population-based surveillance of periodontitis. J Periodontol 78(Suppl 7):1387–1399.

    OpenUrlCrossRefPubMedWeb of Science
27. ↵
    1. Silness J,
    2. Löe H

    (1964) Periodontal disease in pregnancy. II. Correlation between oral hygiene and periodontal condition. Acta Odontol Scand 22:121–135.

    OpenUrlCrossRefPubMed
28. ↵
    1. Löe H,
    2. Silness J

    (1963) Periodontal disease in pregnancy. I. Prevalence and severity. Acta Odontol Scand 21:533–551.

    OpenUrlCrossRefPubMed
29. ↵
    1. Fernández-Real JM,
    2. Ricart W

    (2003) Insulin resistance and chronic cardiovascular inflammatory syndrome. Endocr Rev 24:278–301.

    OpenUrlCrossRefPubMedWeb of Science
30. ↵
    1. Ingelsson E,
    2. Hulthe J,
    3. Lind L

    (2008) Inflammatory markers in relation to insulin resistance and the metabolic syndrome. Eur J Clin Invest 38:502–509.

    OpenUrlCrossRefPubMedWeb of Science
31. ↵
    1. King GL

    (2008) The role of inflammatory cytokines in diabetes and its complications. J Periodontol 79:1527–1534.

    OpenUrlCrossRefPubMedWeb of Science
32. ↵
    1. Al-Mubarak S,
    2. Ciancio S,
    3. Aljada A,
    4. Mohanty P,
    5. Ross C,
    6. Dandona P

    (2002) Comparative evaluation of adjunctive oral irrigation in diabetics. J Clin Periodontol 29:295–300.

    OpenUrlCrossRefPubMedWeb of Science
33. 1. Talbert J,
    2. Elter J,
    3. Jared HL,
    4. Offenbacher S,
    5. Southerland J,
    6. Wilder RS

    (2006) The effect of periodontal therapy on TNF-alpha, IL-6 and metabolic control in type 2 diabetics. J Dent Hyg 80:7.

    OpenUrlFREE Full Text
34. ↵
    1. Lalla E,
    2. Kaplan S,
    3. Yang J,
    4. Roth GA,
    5. Papapanou PN,
    6. Greenberg S

    (2007) Effects of periodontal therapy on serum C-reactive protein, sE-selectin, and tumor necrosis factor-alpha secretion by peripheral blood-derived macrophages in diabetes. A pilot study. J Periodontal Res 42:274–282.

    OpenUrlPubMed
35. ↵
    1. O’Connell PA,
    2. Taba M,
    3. Nomizo A,
    4. Foss Freitas MC,
    5. Suaid FA,
    6. Uyemura SA,
    7. et al.

    (2008) Effects of periodontal therapy on glycemic control and inflammatory markers. J Periodontol 79:774–783.

    OpenUrlCrossRefPubMed
36. ↵
    1. Iwamoto Y,
    2. Nishimura F,
    3. Nakagawa M,
    4. Sugimoto H,
    5. Shikata K,
    6. Makino H,
    7. et al.

    (2001) The effect of antimicrobial periodontal treatment on circulating tumor necrosis factor-alpha and glycated hemoglobin level in patients with type 2 diabetes. J Periodontol 72:774–778.

    OpenUrlCrossRefPubMedWeb of Science
37. ↵
    1. Dag A,
    2. Firat ET,
    3. Arikan S,
    4. Kadiroglu AK,
    5. Kaplan A

    (2009) The effect of periodontal therapy on serum TNF-alpha and HbA1c levels in type 2 diabetic patients. Aust Dent J 54:17–22.

    OpenUrlPubMed
38. ↵
    1. Correa FO,
    2. Goncalves D,
    3. Figueredo CM,
    4. Bastos AS,
    5. Gustafsson A,
    6. Orrico SR

    (2010) Effect of periodontal treatment on metabolic control, systemic inflammation and cytokines in patients with type 2 diabetes. J Clin Periodontol 37:53–58.

    OpenUrlPubMed
39. ↵
    1. Engebretson SP,
    2. Vossughi F,
    3. Hey-Hadavi J,
    4. Emingil G,
    5. Grbic JT

    (2006) The influence of diabetes on gingival crevicular fluid beta-glucuronidase and interleukin-8. J Clin Periodontol 33:784–790.

    OpenUrlPubMed
40. ↵
    1. Duarte PM,
    2. de Oliveira MC,
    3. Tambeli CH,
    4. Parada CA,
    5. Casati MZ,
    6. Nociti FH Jr.

    (2007) Overexpression of interleukin-1beta and interleukin-6 may play an important role in periodontal breakdown in type 2 diabetic patients. J Periodontal Res 42:377–381.

    OpenUrlPubMed
41. ↵
    1. Sun WL,
    2. Chen LL,
    3. Zhang SZ,
    4. Wu YM,
    5. Ren YZ,
    6. Qin GM

    (2011) Inflammatory cytokines, adiponectin, insulin resistance and metabolic control after periodontal intervention in patients with type 2 diabetes and chronic periodontitis. Intern Med 50:1569–1574.

    OpenUrlCrossRefPubMed
42. ↵
    1. Christgau M,
    2. Palitzsch KD,
    3. Schmalz G,
    4. Kreiner U,
    5. Frenzel S

    (1998) Healing response to non-surgical periodontal therapy in patients with diabetes mellitus. Clinical, microbiological, and immunologic results. J Clin Periodontol 25:112–124.

    OpenUrlCrossRefPubMed
43. ↵
    1. Jones JA,
    2. Miller DR,
    3. Wehler CJ,
    4. Rich SE,
    5. Krall-Kaye EA,
    6. McCoy LC,
    7. Christiansen CL,
    8. Rothendler JA,
    9. Garcia RI

    (2007) Does periodontal care improve glycemic control? The Department of Veterans Affairs Dental Diabetes Study. J Clin Periodontol 34:46–52.

    OpenUrlCrossRefPubMed
44. ↵
    1. Navarro-Sanchez AB,
    2. Faria-Almeida R,
    3. Bascones-Martinez A

    (2007) Effect of non-surgical periodontal therapy on clinical and immunological response and glycemic control in type 2 diabetic patients with moderate periodontitis. J Clin Periodontol 34:835–843.

    OpenUrlCrossRefPubMed
45. ↵
    1. Qin XY,
    2. Shen KT,
    3. Zhang X,
    4. Cheng ZH,
    5. Xu XR,
    6. Han ZG

    (2002) Establishment of an artificial cell line expressing insulin under the control of doxycycline. World J Gastroenterol 8:367–370.

    OpenUrlPubMed
46. ↵
    1. Tsalikis L,
    2. Sakellari D,
    3. Dagalis P,
    4. Boura P,
    5. Konstantinidis A

    (2014) Effects of doxycycline on clinical, microbiological and immunological parameters in well-controlled diabetes type- 2 patients with periodontal disease. A randomized controlled clinical trial. J Clin Periodontol 41:972–980.

    OpenUrlCrossRefPubMed
47. ↵
    1. Miranda TS,
    2. Feres M,
    3. Perez-Chaparro PJ,
    4. Faveri M,
    5. Figueiredo LC,
    6. Tamashiro NS,
    7. et al.

    (2014) Metronidazole and amoxicillin as adjuncts to scaling and root planing for the treatment of type 2 diabetic subjects with periodontitis: 1-year outcomes of a randomized placebo-controlled clinical trial. J Clin Periodontol 41:890–899.

    OpenUrlCrossRefPubMed
48. ↵
    1. Tervonen T,
    2. Knuuttila M,
    3. Pohjamo L,
    4. Nurkkala H

    (1991) Immediate response to nonsurgical periodontal treatment in subjects with diabetes mellitus. J Clin Periodontol 18:65–68.

    OpenUrlPubMed
49. ↵
    1. Chapple IL,
    2. Genco R,
    3. Working group 2 of joint EFP/AAP workshop

    (2013) Diabetes and periodontal diseases: consensus report of the Joint EFP/ AAP Workshop on Periodontitis and Systemic Diseases. J Clin Periodontol 40(Suppl 14):S106–S112.

    OpenUrlCrossRefPubMed
50. ↵
    1. Engebretson SP,
    2. Hyman LG,
    3. Michalowicz BS,
    4. Schoenfeld ER,
    5. Gelato MC,
    6. Hou W,
    7. et al.

    (2013) The effect of nonsurgical periodontal therapy on hemoglobin A1c levels in persons with type 2 diabetes and chronic periodontitis: A randomized clinical trial. JAMA 18:2523–2532.

    OpenUrl
51. ↵
    1. Grossi SG,
    2. Zambon J,
    3. Machtei EE,
    4. Schifferle R,
    5. Andreana S,
    6. Genco RJ,
    7. et al.

    (1997) Effects of smoking and smoking cessation on healing after mechanical periodontal therapy. J Am Dent Assoc 128:599–607.

    OpenUrlAbstract/FREE Full Text