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Research ArticleOriginal Article
Open Access

Birth prevalence of non-syndromic orofacial clefts in Saudi Arabia and the effects of parental consanguinity

Heba J. Sabbagh, Nicola P. Innes, Bahauddin I. Sallout, Najlaa M. Alamoudi, Mustafa A. Hamdan, Nasir Alhamlan, Amaal I. Al-Khozami, Fatma D. Abdulhameed, Jumana Y. Al-Aama and Peter A. Mossey
Saudi Medical Journal September 2015, 36 (9) 1076-1083; DOI: https://doi.org/10.15537/smj.2015.9.11823
Heba J. Sabbagh
From the Division of Oral Health Sciences (Sabbagh), Pediatric Dentistry (Innes), Dundee Dental School, Division of Oral Health Sciences and WHO Collaborating Centre for Oral Health and Craniofacial Anomalies (Mossey), University of Dundee, Dundee, Scotland, United Kingdom, Maternal-Fetal Medicine Department (Sallout), Women’s Specialized Hospital, King Fahad Medical City, Plastic Surgery Department (Hamdan), King Saud Medical City, Ministry of Health, Orthodontic Division (Alhamlan), King Abdulaziz Medical City Riyadh, Pediatric Dentistry (Alamoudi), Faculty of Dentistry, Pediatric Department, Nursing Services (Al-Khozami), King Abdulaziz University, Genetic Medicine Department, Faculty of Medicine (Al-Aama), Princess Al-Jawhara Albrahim Centre of Excellence in Research of Hereditary Disorders, King Abdulaziz University Hospital, Jeddah, Pediatric Surgery (Abdulhameed), Maternity and Children’s Hospital, Ministry of Health, Madinah, Kingdom of Saudi Arabia
MSc
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Nicola P. Innes
From the Division of Oral Health Sciences (Sabbagh), Pediatric Dentistry (Innes), Dundee Dental School, Division of Oral Health Sciences and WHO Collaborating Centre for Oral Health and Craniofacial Anomalies (Mossey), University of Dundee, Dundee, Scotland, United Kingdom, Maternal-Fetal Medicine Department (Sallout), Women’s Specialized Hospital, King Fahad Medical City, Plastic Surgery Department (Hamdan), King Saud Medical City, Ministry of Health, Orthodontic Division (Alhamlan), King Abdulaziz Medical City Riyadh, Pediatric Dentistry (Alamoudi), Faculty of Dentistry, Pediatric Department, Nursing Services (Al-Khozami), King Abdulaziz University, Genetic Medicine Department, Faculty of Medicine (Al-Aama), Princess Al-Jawhara Albrahim Centre of Excellence in Research of Hereditary Disorders, King Abdulaziz University Hospital, Jeddah, Pediatric Surgery (Abdulhameed), Maternity and Children’s Hospital, Ministry of Health, Madinah, Kingdom of Saudi Arabia
PhD
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Bahauddin I. Sallout
From the Division of Oral Health Sciences (Sabbagh), Pediatric Dentistry (Innes), Dundee Dental School, Division of Oral Health Sciences and WHO Collaborating Centre for Oral Health and Craniofacial Anomalies (Mossey), University of Dundee, Dundee, Scotland, United Kingdom, Maternal-Fetal Medicine Department (Sallout), Women’s Specialized Hospital, King Fahad Medical City, Plastic Surgery Department (Hamdan), King Saud Medical City, Ministry of Health, Orthodontic Division (Alhamlan), King Abdulaziz Medical City Riyadh, Pediatric Dentistry (Alamoudi), Faculty of Dentistry, Pediatric Department, Nursing Services (Al-Khozami), King Abdulaziz University, Genetic Medicine Department, Faculty of Medicine (Al-Aama), Princess Al-Jawhara Albrahim Centre of Excellence in Research of Hereditary Disorders, King Abdulaziz University Hospital, Jeddah, Pediatric Surgery (Abdulhameed), Maternity and Children’s Hospital, Ministry of Health, Madinah, Kingdom of Saudi Arabia
SBOG
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Najlaa M. Alamoudi
From the Division of Oral Health Sciences (Sabbagh), Pediatric Dentistry (Innes), Dundee Dental School, Division of Oral Health Sciences and WHO Collaborating Centre for Oral Health and Craniofacial Anomalies (Mossey), University of Dundee, Dundee, Scotland, United Kingdom, Maternal-Fetal Medicine Department (Sallout), Women’s Specialized Hospital, King Fahad Medical City, Plastic Surgery Department (Hamdan), King Saud Medical City, Ministry of Health, Orthodontic Division (Alhamlan), King Abdulaziz Medical City Riyadh, Pediatric Dentistry (Alamoudi), Faculty of Dentistry, Pediatric Department, Nursing Services (Al-Khozami), King Abdulaziz University, Genetic Medicine Department, Faculty of Medicine (Al-Aama), Princess Al-Jawhara Albrahim Centre of Excellence in Research of Hereditary Disorders, King Abdulaziz University Hospital, Jeddah, Pediatric Surgery (Abdulhameed), Maternity and Children’s Hospital, Ministry of Health, Madinah, Kingdom of Saudi Arabia
MSc, DSc
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  • For correspondence: [email protected]
Mustafa A. Hamdan
From the Division of Oral Health Sciences (Sabbagh), Pediatric Dentistry (Innes), Dundee Dental School, Division of Oral Health Sciences and WHO Collaborating Centre for Oral Health and Craniofacial Anomalies (Mossey), University of Dundee, Dundee, Scotland, United Kingdom, Maternal-Fetal Medicine Department (Sallout), Women’s Specialized Hospital, King Fahad Medical City, Plastic Surgery Department (Hamdan), King Saud Medical City, Ministry of Health, Orthodontic Division (Alhamlan), King Abdulaziz Medical City Riyadh, Pediatric Dentistry (Alamoudi), Faculty of Dentistry, Pediatric Department, Nursing Services (Al-Khozami), King Abdulaziz University, Genetic Medicine Department, Faculty of Medicine (Al-Aama), Princess Al-Jawhara Albrahim Centre of Excellence in Research of Hereditary Disorders, King Abdulaziz University Hospital, Jeddah, Pediatric Surgery (Abdulhameed), Maternity and Children’s Hospital, Ministry of Health, Madinah, Kingdom of Saudi Arabia
FRCS (Ed)
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Nasir Alhamlan
From the Division of Oral Health Sciences (Sabbagh), Pediatric Dentistry (Innes), Dundee Dental School, Division of Oral Health Sciences and WHO Collaborating Centre for Oral Health and Craniofacial Anomalies (Mossey), University of Dundee, Dundee, Scotland, United Kingdom, Maternal-Fetal Medicine Department (Sallout), Women’s Specialized Hospital, King Fahad Medical City, Plastic Surgery Department (Hamdan), King Saud Medical City, Ministry of Health, Orthodontic Division (Alhamlan), King Abdulaziz Medical City Riyadh, Pediatric Dentistry (Alamoudi), Faculty of Dentistry, Pediatric Department, Nursing Services (Al-Khozami), King Abdulaziz University, Genetic Medicine Department, Faculty of Medicine (Al-Aama), Princess Al-Jawhara Albrahim Centre of Excellence in Research of Hereditary Disorders, King Abdulaziz University Hospital, Jeddah, Pediatric Surgery (Abdulhameed), Maternity and Children’s Hospital, Ministry of Health, Madinah, Kingdom of Saudi Arabia
MOrth RCS (Ed)
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Amaal I. Al-Khozami
From the Division of Oral Health Sciences (Sabbagh), Pediatric Dentistry (Innes), Dundee Dental School, Division of Oral Health Sciences and WHO Collaborating Centre for Oral Health and Craniofacial Anomalies (Mossey), University of Dundee, Dundee, Scotland, United Kingdom, Maternal-Fetal Medicine Department (Sallout), Women’s Specialized Hospital, King Fahad Medical City, Plastic Surgery Department (Hamdan), King Saud Medical City, Ministry of Health, Orthodontic Division (Alhamlan), King Abdulaziz Medical City Riyadh, Pediatric Dentistry (Alamoudi), Faculty of Dentistry, Pediatric Department, Nursing Services (Al-Khozami), King Abdulaziz University, Genetic Medicine Department, Faculty of Medicine (Al-Aama), Princess Al-Jawhara Albrahim Centre of Excellence in Research of Hereditary Disorders, King Abdulaziz University Hospital, Jeddah, Pediatric Surgery (Abdulhameed), Maternity and Children’s Hospital, Ministry of Health, Madinah, Kingdom of Saudi Arabia
BSN
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Fatma D. Abdulhameed
From the Division of Oral Health Sciences (Sabbagh), Pediatric Dentistry (Innes), Dundee Dental School, Division of Oral Health Sciences and WHO Collaborating Centre for Oral Health and Craniofacial Anomalies (Mossey), University of Dundee, Dundee, Scotland, United Kingdom, Maternal-Fetal Medicine Department (Sallout), Women’s Specialized Hospital, King Fahad Medical City, Plastic Surgery Department (Hamdan), King Saud Medical City, Ministry of Health, Orthodontic Division (Alhamlan), King Abdulaziz Medical City Riyadh, Pediatric Dentistry (Alamoudi), Faculty of Dentistry, Pediatric Department, Nursing Services (Al-Khozami), King Abdulaziz University, Genetic Medicine Department, Faculty of Medicine (Al-Aama), Princess Al-Jawhara Albrahim Centre of Excellence in Research of Hereditary Disorders, King Abdulaziz University Hospital, Jeddah, Pediatric Surgery (Abdulhameed), Maternity and Children’s Hospital, Ministry of Health, Madinah, Kingdom of Saudi Arabia
JBPS
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Jumana Y. Al-Aama
From the Division of Oral Health Sciences (Sabbagh), Pediatric Dentistry (Innes), Dundee Dental School, Division of Oral Health Sciences and WHO Collaborating Centre for Oral Health and Craniofacial Anomalies (Mossey), University of Dundee, Dundee, Scotland, United Kingdom, Maternal-Fetal Medicine Department (Sallout), Women’s Specialized Hospital, King Fahad Medical City, Plastic Surgery Department (Hamdan), King Saud Medical City, Ministry of Health, Orthodontic Division (Alhamlan), King Abdulaziz Medical City Riyadh, Pediatric Dentistry (Alamoudi), Faculty of Dentistry, Pediatric Department, Nursing Services (Al-Khozami), King Abdulaziz University, Genetic Medicine Department, Faculty of Medicine (Al-Aama), Princess Al-Jawhara Albrahim Centre of Excellence in Research of Hereditary Disorders, King Abdulaziz University Hospital, Jeddah, Pediatric Surgery (Abdulhameed), Maternity and Children’s Hospital, Ministry of Health, Madinah, Kingdom of Saudi Arabia
FCCMG
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Peter A. Mossey
From the Division of Oral Health Sciences (Sabbagh), Pediatric Dentistry (Innes), Dundee Dental School, Division of Oral Health Sciences and WHO Collaborating Centre for Oral Health and Craniofacial Anomalies (Mossey), University of Dundee, Dundee, Scotland, United Kingdom, Maternal-Fetal Medicine Department (Sallout), Women’s Specialized Hospital, King Fahad Medical City, Plastic Surgery Department (Hamdan), King Saud Medical City, Ministry of Health, Orthodontic Division (Alhamlan), King Abdulaziz Medical City Riyadh, Pediatric Dentistry (Alamoudi), Faculty of Dentistry, Pediatric Department, Nursing Services (Al-Khozami), King Abdulaziz University, Genetic Medicine Department, Faculty of Medicine (Al-Aama), Princess Al-Jawhara Albrahim Centre of Excellence in Research of Hereditary Disorders, King Abdulaziz University Hospital, Jeddah, Pediatric Surgery (Abdulhameed), Maternity and Children’s Hospital, Ministry of Health, Madinah, Kingdom of Saudi Arabia
BDS, PhD
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Birth prevalence of non-syndromic orofacial clefts in Saudi Arabia and the effects of parental consanguinity
Heba J. Sabbagh, Nicola P. Innes, Bahauddin I. Sallout, Najlaa M. Alamoudi, Mustafa A. Hamdan, Nasir Alhamlan, Amaal I. Al-Khozami, Fatma D. Abdulhameed, Jumana Y. Al-Aama, Peter A. Mossey
Saudi Medical Journal Sep 2015, 36 (9) 1076-1083; DOI: 10.15537/smj.2015.9.11823

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Birth prevalence of non-syndromic orofacial clefts in Saudi Arabia and the effects of parental consanguinity
Heba J. Sabbagh, Nicola P. Innes, Bahauddin I. Sallout, Najlaa M. Alamoudi, Mustafa A. Hamdan, Nasir Alhamlan, Amaal I. Al-Khozami, Fatma D. Abdulhameed, Jumana Y. Al-Aama, Peter A. Mossey
Saudi Medical Journal Sep 2015, 36 (9) 1076-1083; DOI: 10.15537/smj.2015.9.11823
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