Skip to main content

Main menu

  • Home
  • Content
    • Latest
    • Archive
    • home
  • Info for
    • Authors
    • Reviewers
    • Subscribers
    • Institutions
    • Advertisers
    • Join SMJ
  • About Us
    • About Us
    • Editorial Office
    • Editorial Board
  • More
    • Advertising
    • Alerts
    • Feedback
    • Folders
    • Help
  • Other Publications
    • NeuroSciences Journal

User menu

  • My alerts
  • Log in

Search

  • Advanced search
Saudi Medical Journal
  • Other Publications
    • NeuroSciences Journal
  • My alerts
  • Log in
Saudi Medical Journal

Advanced Search

  • Home
  • Content
    • Latest
    • Archive
    • home
  • Info for
    • Authors
    • Reviewers
    • Subscribers
    • Institutions
    • Advertisers
    • Join SMJ
  • About Us
    • About Us
    • Editorial Office
    • Editorial Board
  • More
    • Advertising
    • Alerts
    • Feedback
    • Folders
    • Help
  • Follow psmmc on Twitter
  • Visit psmmc on Facebook
  • RSS
Research ArticleOriginal Article
Open Access

The relationship between periapical lesions and the serum levels of glycosylated hemoglobin and C-reactive protein in type 2 diabetic patients

Mohammad S. Al-Zahrani, Basel M. Abozor and Khalid H. Zawawi
Saudi Medical Journal January 2017, 38 (1) 36-40; DOI: https://doi.org/10.15537/smj.2017.1.16052
Mohammad S. Al-Zahrani
From the Departments of Periodontics (Al-Zahrani), Orthodontics (Zawawi), Faculty of Dentistry, King Abdulaziz University, and the Department of Endodontics (Abozor), Ibn Sina National College for Medical Studies, Jeddah, Kingdom of Saudi Arabia
BDS, PhD
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Basel M. Abozor
From the Departments of Periodontics (Al-Zahrani), Orthodontics (Zawawi), Faculty of Dentistry, King Abdulaziz University, and the Department of Endodontics (Abozor), Ibn Sina National College for Medical Studies, Jeddah, Kingdom of Saudi Arabia
BDS, MSc
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • For correspondence: [email protected]
Khalid H. Zawawi
From the Departments of Periodontics (Al-Zahrani), Orthodontics (Zawawi), Faculty of Dentistry, King Abdulaziz University, and the Department of Endodontics (Abozor), Ibn Sina National College for Medical Studies, Jeddah, Kingdom of Saudi Arabia
BDS, DSc
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • Article
  • Figures & Data
  • eLetters
  • Info & Metrics
  • References
  • PDF
Loading

References

  1. ↵
    1. Kao KT,
    2. Sabin MA
    (2016) Type 2 diabetes mellitus in children and adolescents. Aust Fam Physician 45:401–406.
    OpenUrl
  2. ↵
    1. Vega VL,
    2. Charles W,
    3. Crotty Alex,
    4. ander LE
    (2011) Rescuing of deficient killing and phagocytic activities of macrophages derived from non-obese diabetic mice by treatment with geldanamycin or heat shock: potential clinical implications. Cell Stress Chaperones 16:573–581.
    OpenUrlCrossRefPubMedWeb of Science
  3. ↵
    1. Meo SA
    (2016) Prevalence and future prediction of type 2 diabetes mellitus in the Kingdom of Saudi Arabia: A systematic review of published studies. J Pak Med Assoc 66:722–725.
    OpenUrl
  4. ↵
    1. American Diabetes A
    (2012) Diagnosis and classification of diabetes mellitus. Diabetes Care 35(Suppl1):S64–S71.
    OpenUrlFREE Full Text
  5. ↵
    1. Segura-Egea JJ,
    2. Castellanos-Cosano L,
    3. Machuca G,
    4. Lopez-Lopez J,
    5. Martin-Gonzalez J,
    6. Velasco-Ortega E,
    7. et al.
    (2012) Diabetes mellitus, periapical inflammation and endodontic treatment outcome. Med Oral Patol Oral Cir Bucal 17:e356–e361.
    OpenUrlPubMed
  6. ↵
    1. Alzahrani AS,
    2. Bissada NF,
    3. Jurevic RJ,
    4. Narendran S,
    5. Nouneh IE,
    6. Al-Zahrani MS
    (2013) Reduced systemic inflammatory mediators after treatment of chronic gingivitis. Saudi Med J 34:415–419.
    OpenUrl
  7. ↵
    1. Mukhaimer R,
    2. Hussein E,
    3. Orafi I
    (2012) Prevalence of apical periodontitis and quality of root canal treatment in an adult Palestinian sub-population. Saudi Dent J 24:149–155.
    OpenUrlCrossRef
  8. ↵
    1. Casanova L,
    2. Hughes FJ,
    3. Preshaw PM
    (2014) Diabetes and periodontal disease: a two-way relationship. Br Dent J 217:433–437.
    OpenUrl
  9. ↵
    1. Nagpal R,
    2. Yamashiro Y,
    3. Izumi Y
    (2015) The Two-Way Association of Periodontal Infection with Systemic Disorders: An Overview. Mediators Inflamm 2015:793898.
    OpenUrlCrossRef
  10. ↵
    1. Segura-Egea JJ,
    2. Martin-Gonzalez J,
    3. Castellanos-Cosano L
    (2015) Endodontic medicine: connections between apical periodontitis and systemic diseases. Int Endod J 48:933–951.
    OpenUrlCrossRefPubMed
  11. ↵
    1. Garber SE,
    2. Shabahang S,
    3. Escher AP,
    4. Torabinejad M
    (2009) The effect of hyperglycemia on pulpal healing in rats. J Endod 35:60–62.
    OpenUrlPubMed
  12. ↵
    1. Cintra LT,
    2. Samuel RO,
    3. Facundo AC,
    4. Prieto AK,
    5. Sumida DH,
    6. Bomfim SR,
    7. et al.
    (2014) Relationships between oral infections and blood glucose concentrations or HbA1c levels in normal and diabetic rats. Int Endod J 47:228–237.
    OpenUrl
  13. ↵
    1. Segura-Egea JJ,
    2. Jimenez-Pinzon A,
    3. Rios-Santos JV,
    4. Velasco-Ortega E,
    5. Cisneros-Cabello R,
    6. Poyato-Ferrera M
    (2005) High prevalence of apical periodontitis amongst type 2 diabetic patients. Int Endod J 38:564–569.
    OpenUrlCrossRefPubMed
  14. ↵
    1. Mindiola MJ,
    2. Mickel AK,
    3. Sami C,
    4. Jones JJ,
    5. Lalumandier JA,
    6. Nelson SS
    (2006) Endodontic treatment in an American Indian population: a 10-year retrospective study. J Endod 32:828–832.
    OpenUrlPubMed
  15. ↵
    1. Marotta PS,
    2. Fontes TV,
    3. Armada L,
    4. Lima KC,
    5. Rocas IN,
    6. Siqueira JF Jr.
    (2012) Type 2 diabetes mellitus and the prevalence of apical periodontitis and endodontic treatment in an adult Brazilian population. J Endod 38:297–300.
    OpenUrlCrossRefPubMed
  16. ↵
    1. Schulze A,
    2. Schonauer M,
    3. Busse M
    (2007) Sudden improvement of insulin sensitivity related to an endodontic treatment. J Periodontol 78:2380–2384.
    OpenUrlCrossRefPubMed
  17. ↵
    1. Volanakis JE
    (2001) Human C-reactive protein: expression, structure, and function. Mol Immunol 38:189–197.
    OpenUrlCrossRefPubMedWeb of Science
  18. ↵
    1. Belfki H,
    2. Ben Ali S,
    3. Bougatef S,
    4. Ben Ahmed D,
    5. Haddad N,
    6. Jmal A,
    7. et al.
    (2012) Association between C-reactive protein and type 2 diabetes in a Tunisian population. Inflammation 35:684–689.
    OpenUrl
  19. ↵
    1. Dehghan A,
    2. Kardys I,
    3. de Maat MP,
    4. Uitterlinden AG,
    5. Sijbrands EJ,
    6. Bootsma AH,
    7. et al.
    (2007) Genetic variation, C-reactive protein levels, and incidence of diabetes. Diabetes 56:872–878.
    OpenUrlAbstract/FREE Full Text
  20. ↵
    1. Ticinesi A,
    2. Lauretani F,
    3. Nouvenne A,
    4. Porro E,
    5. Fanelli G,
    6. Maggio M,
    7. et al.
    (2016) C-reactive protein (CRP) measurement in geriatric patients hospitalized for acute infection. Eur J Intern Med, pii: S0953-6205(16)30289-8.
  21. ↵
    1. Gomes MS,
    2. Blattner TC,
    3. Sant’Ana Filho M,
    4. Grecca FS,
    5. Hugo FN,
    6. Fouad AF,
    7. et al.
    (2013) Can apical periodontitis modify systemic levels of inflammatory markers?A systematic review and meta-analysis. J Endod 39:1205–1217.
    OpenUrlCrossRefPubMed
  22. ↵
    1. Orstavik D,
    2. Kerekes K,
    3. Eriksen HM
    (1986) The periapical index: a scoring system for radiographic assessment of apical periodontitis. Endod Dent Traumatol 2:20–34.
    OpenUrlCrossRefPubMed
  23. ↵
    1. Kamberi B,
    2. Hoxha V,
    3. Stavileci M,
    4. Dragusha E,
    5. Kuci A,
    6. Kqiku L
    (2011) Prevalence of apical periodontitis and endodontic treatment in a Kosovar adult population. BMC Oral Health 11:32.
    OpenUrlPubMed
  24. ↵
    1. Mesgarani A,
    2. Haghanifar S,
    3. Eshkevari N,
    4. Ehsani M,
    5. Khafri S,
    6. Nafarzade S,
    7. et al.
    (2014) Frequency of odontogenic periradicular lesions in diabetic patients. Caspian J Intern Med 5:22–25.
    OpenUrl
  25. ↵
    1. Doyle SL,
    2. Hodges JS,
    3. Pesun IJ,
    4. Baisden MK,
    5. Bowles WR
    (2007) Factors affecting outcomes for single-tooth implants and endodontic restorations. J Endod 33:399–402.
    OpenUrlCrossRefPubMed
    1. Furusho H,
    2. Miyauchi M,
    3. Hyogo H,
    4. Inubushi T,
    5. Ao M,
    6. Ouhara K,
    7. et al.
    (2013) Dental infection of Porphyromonas gingivalis exacerbates high fat diet-induced steatohepatitis in mice. J Gastroenterol 48:1259–1270.
    OpenUrlCrossRefPubMed
    1. Chuang FH,
    2. Tsai CC,
    3. Chen JH,
    4. Chen KK,
    5. Chen YK,
    6. Lin YC
    (2012) Long-term sequential receptor activator of NF-kappaB ligand (RANKL) and osteoprotegrin (OPG) expression in lipopolysaccharide-induced rat periapical lesions. J Oral Pathol Med 41:186–193.
    OpenUrlPubMed
  26. ↵
    1. Nassar H,
    2. Kantarci A,
    3. van Dyke TE
    (2007) Diabetic periodontitis: a model for activated innate immunity and impaired resolution of inflammation. Periodontol 2000 43:233–244.
    OpenUrlPubMed
  27. ↵
    1. Lima SM,
    2. Grisi DC,
    3. Kogawa EM,
    4. Franco OL,
    5. Peixoto VC,
    6. Goncalves-Junior JF,
    7. et al.
    (2013) Diabetes mellitus and inflammatory pulpal and periapical disease: a review. Int Endod J 46:700–709.
    OpenUrl
  28. ↵
    1. Duarte PM,
    2. Miranda TS,
    3. Lima JA,
    4. Dias Goncalves TE,
    5. Santos VR,
    6. Bastos MF,
    7. et al.
    (2012) Expression of immune-inflammatory markers in sites of chronic periodontitis in patients with type 2 diabetes. J Periodontol 83:426–434.
    OpenUrlPubMed
  29. ↵
    1. Garcia-Hernandez A,
    2. Arzate H,
    3. Gil-Chavarria I,
    4. Rojo R,
    5. Moreno-Fierros L
    (2012) High glucose concentrations alter the biomineralization process in human osteoblastic cells. Bone 50:276–288.
    OpenUrlCrossRefPubMed
PreviousNext
Back to top

In this issue

Saudi Medical Journal: 38 (1)
Saudi Medical Journal
Vol. 38, Issue 1
1 Jan 2017
  • Table of Contents
  • Cover (PDF)
  • Index by author
Print
Download PDF
Email Article

Thank you for your interest in spreading the word on Saudi Medical Journal.

NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.

Enter multiple addresses on separate lines or separate them with commas.
The relationship between periapical lesions and the serum levels of glycosylated hemoglobin and C-reactive protein in type 2 diabetic patients
(Your Name) has sent you a message from Saudi Medical Journal
(Your Name) thought you would like to see the Saudi Medical Journal web site.
Citation Tools
The relationship between periapical lesions and the serum levels of glycosylated hemoglobin and C-reactive protein in type 2 diabetic patients
Mohammad S. Al-Zahrani, Basel M. Abozor, Khalid H. Zawawi
Saudi Medical Journal Jan 2017, 38 (1) 36-40; DOI: 10.15537/smj.2017.1.16052

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
Share
The relationship between periapical lesions and the serum levels of glycosylated hemoglobin and C-reactive protein in type 2 diabetic patients
Mohammad S. Al-Zahrani, Basel M. Abozor, Khalid H. Zawawi
Saudi Medical Journal Jan 2017, 38 (1) 36-40; DOI: 10.15537/smj.2017.1.16052
Twitter logo Facebook logo Mendeley logo
  • Tweet Widget
  • Facebook Like
  • Google Plus One
Bookmark this article

Jump to section

  • Article
    • Abstract
    • Methods
    • Results
    • Discussion
    • Acknowledgment
    • Footnotes
    • References
  • Figures & Data
  • eLetters
  • References
  • Info & Metrics
  • PDF

Related Articles

  • No related articles found.
  • PubMed
  • Google Scholar

Cited By...

  • No citing articles found.
  • Google Scholar

More in this TOC Section

  • The factors affecting comfort and the comfort levels of patients hospitalized in the coronary intensive care unit
  • Exploring communication challenges with children and parents among pharmacists in Saudi Arabia
  • Exploring hypothyroidism’s effects on lipid profiles
Show more Original Article

Similar Articles

CONTENT

  • home

JOURNAL

  • home

AUTHORS

  • home
Saudi Medical Journal

© 2025 Saudi Medical Journal Saudi Medical Journal is copyright under the Berne Convention and the International Copyright Convention.  Saudi Medical Journal is an Open Access journal and articles published are distributed under the terms of the Creative Commons Attribution-NonCommercial License (CC BY-NC). Readers may copy, distribute, and display the work for non-commercial purposes with the proper citation of the original work. Electronic ISSN 1658-3175. Print ISSN 0379-5284.

Powered by HighWire