Research ArticleOriginal Article
Open Access

Assessment of histopathological alterations in patients with chronic hepatitis B infection following long-term oral antiviral therapy

Ahmet Şahin, Mustafa Namıduru, Ayhan Balkan, İlkay Karaoğlan and Murat T. Gülşen
Saudi Medical Journal October 2018, 39 (10) 999-1005; DOI: https://doi.org/10.15537/smj.2018.10.23056

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  • Figure 1
    Figure 1

    Median analysis: A) pre-treatment and post-treatment histological activity index according to treatment duration B) pre-treatment and post-treatment fibrosis scores according to treatment duration.

  • Figure 2
    Figure 2

    Median analysis: A) pre-treatment and post-treatment histological activity index (HAI) according to the treatment initiated B) pre-treatment and post-treatment fibrosis scores according to the treatment initiated.

  • Figure 3
    Figure 3

    Graphic representation of the distribution of histological activity index (HAI) A) and fibrosis scores B) based on liver biopsy at baseline and after 3, 4, and 5 years of treatment with lamividune, entecavir or tenofovir

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