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Research ArticleOriginal Article
Open Access

Molecular and clinical characteristics of very long-chain acyl-CoA dehydrogenase deficiency

A single-center experience in Saudi Arabia

Amal Alhashem, Sarar Mohamed, Manal Abdelraheem, Bushra AlGufaydi and Aida Al-Aqeel
Saudi Medical Journal June 2020, 41 (6) 590-596; DOI: https://doi.org/10.15537/smj.2020.6.25131
Amal Alhashem
From the Department of Pediatrics (Alhashem, Abdelrahim, AlGufaydi, Al-Aqeel, Mohamed), Prince Sultan Military Medical City; from the Department of Pediatrics (Alhashem, Mohamed); from the Department of Anatomy and Embryology (Al-Aqeel), College of Medicine, AlFaisal University; from Prince Abdullah bin Khalid Celiac Disease Research Chair (Mohamed), King Saud University, Riyadh, Kingdom of Saudi Arabia; and from the Department of Biochemistry and Molecular Biology (Al-Aqeel), College of Medicine, American University of Beirut, Beirut, Lebanon.
MD, FMG
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Sarar Mohamed
From the Department of Pediatrics (Alhashem, Abdelrahim, AlGufaydi, Al-Aqeel, Mohamed), Prince Sultan Military Medical City; from the Department of Pediatrics (Alhashem, Mohamed); from the Department of Anatomy and Embryology (Al-Aqeel), College of Medicine, AlFaisal University; from Prince Abdullah bin Khalid Celiac Disease Research Chair (Mohamed), King Saud University, Riyadh, Kingdom of Saudi Arabia; and from the Department of Biochemistry and Molecular Biology (Al-Aqeel), College of Medicine, American University of Beirut, Beirut, Lebanon.
FRCPCH, MD
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Manal Abdelraheem
From the Department of Pediatrics (Alhashem, Abdelrahim, AlGufaydi, Al-Aqeel, Mohamed), Prince Sultan Military Medical City; from the Department of Pediatrics (Alhashem, Mohamed); from the Department of Anatomy and Embryology (Al-Aqeel), College of Medicine, AlFaisal University; from Prince Abdullah bin Khalid Celiac Disease Research Chair (Mohamed), King Saud University, Riyadh, Kingdom of Saudi Arabia; and from the Department of Biochemistry and Molecular Biology (Al-Aqeel), College of Medicine, American University of Beirut, Beirut, Lebanon.
MD, MRCPCH
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Bushra AlGufaydi
From the Department of Pediatrics (Alhashem, Abdelrahim, AlGufaydi, Al-Aqeel, Mohamed), Prince Sultan Military Medical City; from the Department of Pediatrics (Alhashem, Mohamed); from the Department of Anatomy and Embryology (Al-Aqeel), College of Medicine, AlFaisal University; from Prince Abdullah bin Khalid Celiac Disease Research Chair (Mohamed), King Saud University, Riyadh, Kingdom of Saudi Arabia; and from the Department of Biochemistry and Molecular Biology (Al-Aqeel), College of Medicine, American University of Beirut, Beirut, Lebanon.
MD, ABP
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Aida Al-Aqeel
From the Department of Pediatrics (Alhashem, Abdelrahim, AlGufaydi, Al-Aqeel, Mohamed), Prince Sultan Military Medical City; from the Department of Pediatrics (Alhashem, Mohamed); from the Department of Anatomy and Embryology (Al-Aqeel), College of Medicine, AlFaisal University; from Prince Abdullah bin Khalid Celiac Disease Research Chair (Mohamed), King Saud University, Riyadh, Kingdom of Saudi Arabia; and from the Department of Biochemistry and Molecular Biology (Al-Aqeel), College of Medicine, American University of Beirut, Beirut, Lebanon.
FRCP, FACMG
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Article Information

vol. 41 no. 6 590-596
DOI 
https://doi.org/10.15537/smj.2020.6.25131
PubMed 
32518924

Published By 
Saudi Medical Journal
Online ISSN 
1658-3175
History 
  • Received April 7, 2020
  • Accepted May 20, 2020
  • Published online June 1, 2020.

Copyright & Usage 
Copyright: © Saudi Medical Journal This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Author Information

  1. Amal Alhashem, MD, FMG,
  2. Sarar Mohamed, FRCPCH, MD⇑,
  3. Manal Abdelraheem, MD, MRCPCH,
  4. Bushra AlGufaydi, MD, ABP and
  5. Aida Al-Aqeel, FRCP, FACMG
  1. From the Department of Pediatrics (Alhashem, Abdelrahim, AlGufaydi, Al-Aqeel, Mohamed), Prince Sultan Military Medical City; from the Department of Pediatrics (Alhashem, Mohamed); from the Department of Anatomy and Embryology (Al-Aqeel), College of Medicine, AlFaisal University; from Prince Abdullah bin Khalid Celiac Disease Research Chair (Mohamed), King Saud University, Riyadh, Kingdom of Saudi Arabia; and from the Department of Biochemistry and Molecular Biology (Al-Aqeel), College of Medicine, American University of Beirut, Beirut, Lebanon.
  1. Address correspondence and reprint request to: Dr. Sarar Mohamed, Prince Sultan Military Medical City, Riyadh, Kingdom of Saudi Arabia. E-amil: [email protected] ORCID ID: https://orcid.org./0000-0002-7393-5064
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Molecular and clinical characteristics of very long-chain acyl-CoA dehydrogenase deficiency
Amal Alhashem, Sarar Mohamed, Manal Abdelraheem, Bushra AlGufaydi, Aida Al-Aqeel
Saudi Medical Journal Jun 2020, 41 (6) 590-596; DOI: 10.15537/smj.2020.6.25131

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Molecular and clinical characteristics of very long-chain acyl-CoA dehydrogenase deficiency
Amal Alhashem, Sarar Mohamed, Manal Abdelraheem, Bushra AlGufaydi, Aida Al-Aqeel
Saudi Medical Journal Jun 2020, 41 (6) 590-596; DOI: 10.15537/smj.2020.6.25131
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Keywords

  • clinical characteristics
  • clinical
  • molecular
  • Saudi Arabia
  • VLCAD deficiency

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