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Research ArticleOriginal Article
Open Access

Outcomes and complications of pharmacological induction of labor in women with previous one cesarean section, in a referral center in Saudi Arabia

Aisha I. Alshitwi, Bilquis U. Begum, Farahat N. Kamal, Shazia Aslam, Hend M. Hamido and Gehan M. Atef
Saudi Medical Journal October 2021, 42 (10) 1078-1082; DOI: https://doi.org/10.15537/smj.2021.42.10.20210180
Aisha I. Alshitwi
From the Department of Obstetrics and Gynecology, King Saud Medical City, Riyadh, Kingdom of Saudi Arabia.
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Bilquis U. Begum
From the Department of Obstetrics and Gynecology, King Saud Medical City, Riyadh, Kingdom of Saudi Arabia.
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Farahat N. Kamal
From the Department of Obstetrics and Gynecology, King Saud Medical City, Riyadh, Kingdom of Saudi Arabia.
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Shazia Aslam
From the Department of Obstetrics and Gynecology, King Saud Medical City, Riyadh, Kingdom of Saudi Arabia.
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Hend M. Hamido
From the Department of Obstetrics and Gynecology, King Saud Medical City, Riyadh, Kingdom of Saudi Arabia.
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Gehan M. Atef
From the Department of Obstetrics and Gynecology, King Saud Medical City, Riyadh, Kingdom of Saudi Arabia.
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  • For correspondence: [email protected]
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    Figure 1

    - Indications for Induction of labor. PROM: premature rupture of membranes, prolong: prolonged pregnancy beyond 41 weeks, GDM: gestational diabetes mellitus

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    Figure 2

    - Indications of CS in failed IOL subgroup. CS: caesarean section, IOL: induction of labor

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    Table 1

    - Comparison of successful and failed induction of labor (IOL) subgroups.

    VariablesSuccessful IOL (n=86)Failed IOL (n=59)P-value
    Age (years): mean ± SD26.4 ± 5.925.6 ± 60.4270
    Gestational age (weeks): mean ± SD40.6 ± 0.540.7 ± 0.40.2025
    Parity (n, %)
    Para 130 (35.0)34 (57.6)0.01
    Multiparous56 (65.0)25 (42.4)0.01
    Indication of IOL
    PROM24 (28.0)22 (37.3)0.2390
    Prolonged pregnancy22 (25.5)17 (28.8)0.6607
    GDM12 (14.0)11 (18.6)0.4580
    Non-reassuring CTG19 (22.1)7 (11.9)0.1172
    Other9 (10.4)2 (3.4)0.1183
    Prostin dose (mg): mean ± SD3.2 ± 0.25.3 ± 0.3<0.001*
    Syntocinon augmentation (n, %)5 (5.8)8 (13.6)0.1077
    Maternal complications (n, %)
    None83 (96.5)55 (93.2)0.364
    Abruptio placenta1 (1.2)1 (1.7)1.000
    Rupture uterus0 (0)2 (3.4)0.086
    Vaginal tear2 (2.3)0 (0)0.242
    Post-partum hemorrhage0 (0)1 (1.7)0.354
    Fetal complications
    None85 (98.8)56 (94.9)0.1625
    Shoulder dystocia1 (1.2)0 (0)0.4001
    Neonatal hypoxia0 (0)1 (1.7)0.2266
    IUFD0 (0)2 (3.4)0.0862

    PROM: premature rupture of membranes, GDM: gestational diabetes mellitus, CTG: cardio tocograph,

    IUFD: intrauterine fetal death, *Statistically significant at 5% level, IOL: induction of labor

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    Saudi Medical Journal: 42 (10)
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    1 Oct 2021
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    Outcomes and complications of pharmacological induction of labor in women with previous one cesarean section, in a referral center in Saudi Arabia
    Aisha I. Alshitwi, Bilquis U. Begum, Farahat N. Kamal, Shazia Aslam, Hend M. Hamido, Gehan M. Atef
    Saudi Medical Journal Oct 2021, 42 (10) 1078-1082; DOI: 10.15537/smj.2021.42.10.20210180

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    Outcomes and complications of pharmacological induction of labor in women with previous one cesarean section, in a referral center in Saudi Arabia
    Aisha I. Alshitwi, Bilquis U. Begum, Farahat N. Kamal, Shazia Aslam, Hend M. Hamido, Gehan M. Atef
    Saudi Medical Journal Oct 2021, 42 (10) 1078-1082; DOI: 10.15537/smj.2021.42.10.20210180
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    Keywords

    • outcomes
    • induction of labor
    • vaginal delivery
    • cesarean section
    • Saudi Arabia

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