Caffeine modulates pharmacokinetic and pharmacodynamic profiles of pioglitazone in diabetic rats: Impact on therapeutics

Ali M. Alshabi; Saad A. Alkahtani; Ibrahim A. Shaikh; Mohammed S. Habeeb

doi:10.15537/smj.2021.2.25695

Research ArticleOriginal Article

Open Access

Caffeine modulates pharmacokinetic and pharmacodynamic profiles of pioglitazone in diabetic rats

Impact on therapeutics

Ali M. Alshabi, Saad A. Alkahtani, Ibrahim A. Shaikh and Mohammed S. Habeeb

Saudi Medical Journal February 2021, 42 (2) 151-160; DOI: https://doi.org/10.15537/smj.2021.2.25695

Ali M. Alshabi

From the Department of Clinical Pharmacy (Alshabi, Alkahtani), and from the Department of Pharmacology (Shaikh, Habeeb), College of Pharmacy, Najran University, Najran, Kingdom of Saudi Arabia.

M.Pharm, PhD

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site
For correspondence: [email protected]

Saad A. Alkahtani

From the Department of Clinical Pharmacy (Alshabi, Alkahtani), and from the Department of Pharmacology (Shaikh, Habeeb), College of Pharmacy, Najran University, Najran, Kingdom of Saudi Arabia.

M.Pharm, PhD

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Ibrahim A. Shaikh

From the Department of Clinical Pharmacy (Alshabi, Alkahtani), and from the Department of Pharmacology (Shaikh, Habeeb), College of Pharmacy, Najran University, Najran, Kingdom of Saudi Arabia.

M.Pharm

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Mohammed S. Habeeb

From the Department of Clinical Pharmacy (Alshabi, Alkahtani), and from the Department of Pharmacology (Shaikh, Habeeb), College of Pharmacy, Najran University, Najran, Kingdom of Saudi Arabia.

M.Pharm

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Article
Figures & Data
eLetters
Info & Metrics
References
PDF

Article Information

vol. 42 no. 2 151-160

DOI

https://doi.org/10.15537/smj.2021.2.25695

PubMed

33563733

Published By

Saudi Medical Journal

Online ISSN

1658-3175

History

Received December 18, 2020
Accepted January 6, 2021
Published online February 9, 2021.

Copyright: © Saudi Medical Journal This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial License (CC BY-NC), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Author Information

Ali M. Alshabi, M.Pharm, PhD ⇑,
Saad A. Alkahtani, M.Pharm, PhD,
Ibrahim A. Shaikh, M.Pharm and
Mohammed S. Habeeb, M.Pharm

From the Department of Clinical Pharmacy (Alshabi, Alkahtani), and from the Department of Pharmacology (Shaikh, Habeeb), College of Pharmacy, Najran University, Najran, Kingdom of Saudi Arabia.

Address correspondence and reprint request to: Dr. Ali M. Alshabi, Vice Dean, Academic Affairs, Department of Clinical Pharmacy, College of Pharmacy, Najran University, Najran, Kingdom of Saudi Arabia. E-mail: dr.aliresearch19{at}gmail.com ORCID ID: https://orcid.org/0000-0002-9346-2559

View Full Text

Cited By...

12 Citations
11 Citations
Google Scholar

This article has been cited by the following articles in journals that are participating in Crossref Cited-by Linking.

Caffeine in liver diseases: Pharmacology and toxicology

Liang Shan, Fengling Wang, Dandan Zhai, Xiangyun Meng, Jianjun Liu, Xiongwen Lv

Frontiers in Pharmacology 2022 13
Synergistic Effects of Caffeine in Combination with Conventional Drugs: Perspectives of a Drug That Never Ages

Davide Ialongo, Valeria Tudino, Merve Arpacioglu, Antonella Messore, Elisa Patacchini, Roberta Costi, Roberto Di Santo, Valentina Noemi Madia

Pharmaceuticals 2023 16 5
Phytochemicals from Corchorus olitorius methanolic extract induce apoptotic cell death via activation of caspase-3, anti-Bcl-2 activity, and DNA degradation in breast and lung cancer cell lines

Ali Mohamed Alshabi, Saad Ahmed Alkahtani, Ibrahim Ahmed Shaikh, Mohamed A.A. Orabi, Basel A. Abdel-Wahab, Ismail A. Walbi, Mohammed S. Habeeb, Masood Medleri Khateeb, Joy H. Hoskeri, Arun K. Shettar, Syed Mohammed Basheeruddin Asdaq

Journal of King Saud University - Science 2022 34 7
The inhibitory effects of Dulaglutide on cellular senescence against high glucose in human retinal endothelial cells

Shen Nian, Yajing Mi, Kai Ren, Shanwei Wang, Mingkai Li, Di Yang

Human Cell 2022 35 4
Bee venom ameliorates cardiac dysfunction in diabetic hyperlipidemic rats

Faten Zahran, Alaa Mohamad, Nabila Zein

Experimental Biology and Medicine 2021 246 24
Cardiorespiratory and Neuroprotective Effects of Caffeine in Neonate Animal Models

Daniel Mota-Rojas, Dina Villanueva-García, Ismael Hernández-Ávalos, Alejandro Casas-Alvarado, Adriana Domínguez-Oliva, Karina Lezama-García, Agatha Miranda-Cortés, Julio Martínez-Burnes

Animals 2023 13 11
Modulatory Effects of Caffeine and Pentoxifylline on Aromatic Antibiotics: A Role for Hetero-Complex Formation

Anna Woziwodzka, Marta Krychowiak-Maśnicka, Grzegorz Gołuński, Anna Felberg, Agnieszka Borowik, Dariusz Wyrzykowski, Jacek Piosik

Molecules 2021 26 12
Caffeine in Hepatocellular Carcinoma: Cellular Assays, Animal Experiments, and Epidemiological Investigation

Liang Shan, Ning Zhao, Fengling Wang, Dandan Zhai, Jianjun Liu, Xiongwen Lv

Journal of Inflammation Research 2024 Volume 17
Synthesis, biological evaluation and molecular docking studies of 8-(hetero)aryl caffeine derivatives

Siraj Khan, Nesrin Buğday, Şeyma Yaşar, Asim.ur. Rehman, Ihsan Ul Haq, Sedat Yaşar

Journal of Organometallic Chemistry 2023 997
Phenyl glycine incorporated glitazones as promising novel antidiabetic agents through PPARγ agonism: Design, synthesis and preclinical studies

Subhankar Mandal, Devi Sri Chiriki, B.M. Gurupadayya, I.A. Chethan, B.R. Prashantha Kumar

European Journal of Medicinal Chemistry Reports 2022 6
Profiling of Potential Anti-Diabetic Active Compounds in White Tea: An Integrated Study of Polyphenol-Targeted Metabolomics, Network Pharmacology, and Computer Simulation

Weiwei Wu, Zhiqiang Zheng, Zhihui Wang, Chenxi Gao, Yilin Liang, Wen Zeng, Weijiang Sun

Foods 2024 13 21

PreviousNext

In this issue

Saudi Medical Journal

Vol. 42, Issue 2

1 Feb 2021

Table of Contents
Cover (PDF)
Index by author

Download PDF

Email Article

Thank you for your interest in spreading the word on Saudi Medical Journal.

NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.

Your Email *

Your Name *

Send To *

Enter multiple addresses on separate lines or separate them with commas.

You are going to email the following Caffeine modulates pharmacokinetic and pharmacodynamic profiles of pioglitazone in diabetic rats

Message Subject (Your Name) has sent you a message from Saudi Medical Journal

Message Body (Your Name) thought you would like to see the Saudi Medical Journal web site.

Your Personal Message

Citation Tools

Caffeine modulates pharmacokinetic and pharmacodynamic profiles of pioglitazone in diabetic rats

Ali M. Alshabi, Saad A. Alkahtani, Ibrahim A. Shaikh, Mohammed S. Habeeb

Saudi Medical Journal Feb 2021, 42 (2) 151-160; DOI: 10.15537/smj.2021.2.25695

Citation Manager Formats

BibTeX
Bookends
EasyBib
EndNote (tagged)
EndNote 8 (xml)
Medlars
Mendeley
Papers
RefWorks Tagged
Ref Manager
RIS
Zotero

Caffeine modulates pharmacokinetic and pharmacodynamic profiles of pioglitazone in diabetic rats

Ali M. Alshabi, Saad A. Alkahtani, Ibrahim A. Shaikh, Mohammed S. Habeeb

Saudi Medical Journal Feb 2021, 42 (2) 151-160; DOI: 10.15537/smj.2021.2.25695

Share This Article:

Tweet Widget
Facebook Like
Google Plus One

Bookmark this article

User Name *

Password *

Remember my user name & password.

Jump to section

Article
Figures & Data
eLetters
References
Info & Metrics
PDF

No related articles found.

PubMed
Google Scholar

Cited By...

No citing articles found.

Google Scholar

Keywords

caffeine
pioglitazone
antidiabetic
pharmacokinetic
pharmacodynamic

Main menu

User menu

Search

Caffeine modulates pharmacokinetic and pharmacodynamic profiles of pioglitazone in diabetic rats

Impact on therapeutics

Article Information

Author Information

Cited By...

In this issue

Citation Manager Formats

Related Articles

Cited By...

More in this TOC Section

Similar Articles

Keywords

CONTENT

JOURNAL

AUTHORS