Skip to main content

Main menu

  • Home
  • Content
    • Latest
    • Archive
    • home
  • Info for
    • Authors
    • Reviewers
    • Subscribers
    • Institutions
    • Advertisers
    • Join SMJ
  • About Us
    • About Us
    • Editorial Office
    • Editorial Board
  • More
    • Advertising
    • Alerts
    • Feedback
    • Folders
    • Help
  • Other Publications
    • NeuroSciences Journal

User menu

  • My alerts
  • Log in

Search

  • Advanced search
Saudi Medical Journal
  • Other Publications
    • NeuroSciences Journal
  • My alerts
  • Log in
Saudi Medical Journal

Advanced Search

  • Home
  • Content
    • Latest
    • Archive
    • home
  • Info for
    • Authors
    • Reviewers
    • Subscribers
    • Institutions
    • Advertisers
    • Join SMJ
  • About Us
    • About Us
    • Editorial Office
    • Editorial Board
  • More
    • Advertising
    • Alerts
    • Feedback
    • Folders
    • Help
  • Follow psmmc on Twitter
  • Visit psmmc on Facebook
  • RSS
Case ReportCase Report
Open Access

Insulinoma in tuberous sclerosis

An entity not to be missed

Mohammed S. Al Qahtani, Shoukat A. Bojal, Abdullah A. Alqarzaie and Abdulaziz A. Alqahtani
Saudi Medical Journal March 2021, 42 (3) 332-337; DOI: https://doi.org/10.15537/smj.2021.42.3.20200490
Mohammed S. Al Qahtani
From the Department of Surgery (Al Qahtani M), Multi Organ Transplant Center; from the Department of Surgery (Bojal), King Fahad Specialist Hospital; and from the College of Medicine (Alqarzaie, Alqahtani A) Imam Abdulrahman Bin Faisal University, Dammam, Kingdom of Saudi Arabia.
MD, EMSHA
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • For correspondence: [email protected]
Shoukat A. Bojal
From the Department of Surgery (Al Qahtani M), Multi Organ Transplant Center; from the Department of Surgery (Bojal), King Fahad Specialist Hospital; and from the College of Medicine (Alqarzaie, Alqahtani A) Imam Abdulrahman Bin Faisal University, Dammam, Kingdom of Saudi Arabia.
MBBS, FRCS
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Abdullah A. Alqarzaie
From the Department of Surgery (Al Qahtani M), Multi Organ Transplant Center; from the Department of Surgery (Bojal), King Fahad Specialist Hospital; and from the College of Medicine (Alqarzaie, Alqahtani A) Imam Abdulrahman Bin Faisal University, Dammam, Kingdom of Saudi Arabia.
MBBS
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Abdulaziz A. Alqahtani
From the Department of Surgery (Al Qahtani M), Multi Organ Transplant Center; from the Department of Surgery (Bojal), King Fahad Specialist Hospital; and from the College of Medicine (Alqarzaie, Alqahtani A) Imam Abdulrahman Bin Faisal University, Dammam, Kingdom of Saudi Arabia.
MBBS
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • Article
  • Figures & Data
  • eLetters
  • Info & Metrics
  • References
  • PDF
Loading

Article Figures & Data

Figures

  • Tables
  • Figure 1
    • Download figure
    • Open in new tab
    • Download powerpoint
    Figure 1

    - The patient was injected with 25 mCi of Tc-99m tektrotyd (octreotide) followed by scan of the whole body and static images and single photon emission computed tomography (SPECT)/CT for chest, abdomen, and pelvis. Above images show scintigraphic evidence of octreotide avid lesion in the pancreatic head A) coronal view, B) axial view, C) parasagittal SPECT/CT images. D) Shows maximum intensity projection (MIP) image, with arrow pointing to the head of pancreas, showing octreotide avid lesion.

  • Figure 2
    • Download figure
    • Open in new tab
    • Download powerpoint
    Figure 2

    - Timeline flowchart of the patient with a diagnosis of tuberous sclerosis complex.

  • Figure 3
    • Download figure
    • Open in new tab
    • Download powerpoint
    Figure 3

    - A) Histological examination shows diffuse infiltration by bland-looking neoplastic epithelial cells arranged in cords, solid nests, and trabeculae (×100, hematoxylin and eosin). B) The neoplastic cells are small to medium sized showing low grade neuroendocrine features in the form of very rare mitotic figures, a salt-and-pepper chromatin pattern, uniform round nuclei, and a rim of amphophilic finely granular cytoplasm, (black arrow) (×200, Hematoxylin&Eosin). C) Diffusely positive neoplastic cells for neuroendocrine markers, chromogranin and synaptophysin (black arrow), (x100). D) Immunohistochemical stain for Ki67 highlights the very low mitotic activity of these neoplastic cells, less than 2% (black arrows), (x 200).

Tables

  • Figures
    • View popup
    Table 1

    - Literature review of insulinoma cases in tuberous sclerosis complex patients.

    DemographicsTumor characteristicsReferences
    GenderAge (years)Size(cm)Site in the pancreas
    F243Body(10)
    M233Head(11)
    M282Tail(12)
    M182.9Head(13)
    M4321Not clearly
    mentioned
    (8)
    M23Tumor 1: 3.5
    Tumor 2: 0.7
    Tail(3)
    F671.5Uncinate process(5)
    M: male, F: female
PreviousNext
Back to top

In this issue

Saudi Medical Journal: 42 (3)
Saudi Medical Journal
Vol. 42, Issue 3
1 Mar 2021
  • Table of Contents
  • Index by author
Print
Download PDF
Email Article

Thank you for your interest in spreading the word on Saudi Medical Journal.

NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.

Enter multiple addresses on separate lines or separate them with commas.
Insulinoma in tuberous sclerosis
(Your Name) has sent you a message from Saudi Medical Journal
(Your Name) thought you would like to see the Saudi Medical Journal web site.
Citation Tools
Insulinoma in tuberous sclerosis
Mohammed S. Al Qahtani, Shoukat A. Bojal, Abdullah A. Alqarzaie, Abdulaziz A. Alqahtani
Saudi Medical Journal Mar 2021, 42 (3) 332-337; DOI: 10.15537/smj.2021.42.3.20200490

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
Share
Insulinoma in tuberous sclerosis
Mohammed S. Al Qahtani, Shoukat A. Bojal, Abdullah A. Alqarzaie, Abdulaziz A. Alqahtani
Saudi Medical Journal Mar 2021, 42 (3) 332-337; DOI: 10.15537/smj.2021.42.3.20200490
Twitter logo Facebook logo Mendeley logo
  • Tweet Widget
  • Facebook Like
  • Google Plus One
Bookmark this article

Jump to section

  • Article
    • Abstract
    • Case Report
    • Discussion
    • Acknowledgment
    • Footnotes
    • References
  • Figures & Data
  • eLetters
  • References
  • Info & Metrics
  • PDF

Related Articles

  • No related articles found.
  • PubMed
  • Google Scholar

Cited By...

  • Comment on: Insulinoma in tuberous sclerosis: an entity not to be missed
  • Google Scholar

More in this TOC Section

  • Cutaneous metastasis of signet ring cell adenocarcinoma of the colon
  • Giant left gastric artery aneurysm with intrathoracic extension
  • A rare case of a horseshoe kidney with a single left-sided ureter presented with recurrent urinary tract infection
Show more Case Report

Similar Articles

Keywords

  • insulinoma
  • neuroendocrine tumors
  • tuberous sclerosis
  • case reports
  • review

CONTENT

  • home

JOURNAL

  • home

AUTHORS

  • home
Saudi Medical Journal

© 2025 Saudi Medical Journal Saudi Medical Journal is copyright under the Berne Convention and the International Copyright Convention.  Saudi Medical Journal is an Open Access journal and articles published are distributed under the terms of the Creative Commons Attribution-NonCommercial License (CC BY-NC). Readers may copy, distribute, and display the work for non-commercial purposes with the proper citation of the original work. Electronic ISSN 1658-3175. Print ISSN 0379-5284.

Powered by HighWire