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Research ArticleOriginal Article
Open Access

Age and gender differences in the prevalence of chronic diseases and atherosclerotic cardiovascular disease risk scores in adults in Riyadh city, Saudi Arabia

AlJohara M. AlQuaiz, Ambreen Kazi, Abdulaziz A. Alodhayani, Aljohara Almeneessier, Khaled M. AlHabeeb and Amna R. Siddiqui
Saudi Medical Journal May 2021, 42 (5) 526-536; DOI: https://doi.org/10.15537/smj.2021.42.5.20200684
AlJohara M. AlQuaiz
From the Princess Nora Bent Abdullah Chair for Women’s Health Research (AlQuaiz, Kazi, Almeneessier, AlHabeeb, Siddiqui), Deanship of Research Chairs Program, and from the Department of Family & Community Medicine (AlQuaiz, Kazi, AlOdhayani), College of Medicine, King Saud University Medical City, King Saud University, Riyadh, Kingdom of Saudi Arabia.
MD, MRCGP
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Ambreen Kazi
From the Princess Nora Bent Abdullah Chair for Women’s Health Research (AlQuaiz, Kazi, Almeneessier, AlHabeeb, Siddiqui), Deanship of Research Chairs Program, and from the Department of Family & Community Medicine (AlQuaiz, Kazi, AlOdhayani), College of Medicine, King Saud University Medical City, King Saud University, Riyadh, Kingdom of Saudi Arabia.
MCPS, FCPS
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  • For correspondence: [email protected]
Abdulaziz A. Alodhayani
From the Princess Nora Bent Abdullah Chair for Women’s Health Research (AlQuaiz, Kazi, Almeneessier, AlHabeeb, Siddiqui), Deanship of Research Chairs Program, and from the Department of Family & Community Medicine (AlQuaiz, Kazi, AlOdhayani), College of Medicine, King Saud University Medical City, King Saud University, Riyadh, Kingdom of Saudi Arabia.
MD, SBFM
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Aljohara Almeneessier
From the Princess Nora Bent Abdullah Chair for Women’s Health Research (AlQuaiz, Kazi, Almeneessier, AlHabeeb, Siddiqui), Deanship of Research Chairs Program, and from the Department of Family & Community Medicine (AlQuaiz, Kazi, AlOdhayani), College of Medicine, King Saud University Medical City, King Saud University, Riyadh, Kingdom of Saudi Arabia.
MD, ABFM
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Khaled M. AlHabeeb
From the Princess Nora Bent Abdullah Chair for Women’s Health Research (AlQuaiz, Kazi, Almeneessier, AlHabeeb, Siddiqui), Deanship of Research Chairs Program, and from the Department of Family & Community Medicine (AlQuaiz, Kazi, AlOdhayani), College of Medicine, King Saud University Medical City, King Saud University, Riyadh, Kingdom of Saudi Arabia.
BDS
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Amna R. Siddiqui
From the Princess Nora Bent Abdullah Chair for Women’s Health Research (AlQuaiz, Kazi, Almeneessier, AlHabeeb, Siddiqui), Deanship of Research Chairs Program, and from the Department of Family & Community Medicine (AlQuaiz, Kazi, AlOdhayani), College of Medicine, King Saud University Medical City, King Saud University, Riyadh, Kingdom of Saudi Arabia.
FCPS, PhD
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    Figure 1

    - Prevalence of diabetes mellitus in Saudi men and women by age categories in Riyadh city, Saudi Arabia.

  • Figure 2
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    Figure 2

    - Prevalence of central obesity in Saudi men and women by age categories in Riyadh city, Saudi Arabia.

Tables

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    Table 1

    - Sociodemographic characteristics and anthropometric measurements of Saudi males and females in Riyadh city, Saudi Arabia.

    CharacteristicsMales (n=968)Females (n=2029)P-value
    Age (years)<0.07
    30- 39435 (44.9)838 (41.3)
    40- 49275 (28.4)577 (28.4)
    50- 59151 (15.6)392 (19.3)
    60- 75107 (11.1)222 (10.9)
    Participants education<0.01
    Secondary & below254 (26.2)1153 (56.8)
    University & above714 (73.8)876 (43.2)
    Spouse education (n=2749)<0.01
    Intermediate & below392 (45.3)1122 (59.6)
    University & above474 (54.7)761 (40.4)
    Participants occupation<0.01
    Working852 (88.0)858 (42.3)
    Not working116 (12.0)1171 (57.7)
    Spouse occupation (n=2749)<0.01
    Working632 (73.0)1322 (70.2)
    Not working234 (27.0)561 (29.8)
    Housing type<0.01
    Traditional Arabic house51 (5.3)273 (13.5)
    Apartment341 (35.2)474 23.4)
    Villa576 (59.5)1280 (63.1)
    Monthly income SAR (n=2661)<0.01
    ≤10,000320 (33.9)986 (57.4)
    >10,000623 (66.1)732 (42.6)
    Current smoker<0.01
    Yes268 (27.7)44 (2.2)
    No700 (72.3)1985 (97.8)
    • * P-values calculated to measure significant difference between men and women using the Chi-square test

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    Table 2

    - Prevalence of chronic diseases (diagnosed and screened)a in Saudi males and females in Riyadh city, Saudi Arabia.

    DiseaseDiagnosed and screenedTotal prevalence
    Diabetes mellitusDiagnosed casesb Males =162, Females=438Raised HbA1c on screening (≥6.5)Total prevalencec (N=2962) (both diagnosed and screened) Males=961, Females=2001
    Controlled HbA1c ≤7.0Uncontrolled HbA1c >7.0
    Male70 (7.3)92 (9.6)33 (4.1)195 (20.3)
    Female203 (10.1)235 (11.8)59 (2.9)497 (24.8)*
    Total273 (9.3)327 (11.0)92 (3.1)692 (23.4)
    HypertensionDiagnosed casesbMales= 145, Females= 396Raised blood pressure reading on screening only > 140 or/and > 90Total prevalencec (N=2987) (only physician diagnosed) Males=968,Females=2029 Total=2987
    Controlled <140 and <90Uncontrolled≥ 140 or/and ≥ 90
    Males63 (6.5)82 (8.5)134 (16.3)145 (15.0)
    Females225(11.1)171 (8.4)**148 (9.1)396 (19.5)
    Total288 (9.6)253 (8.4)282 (11.5)541 (18.1)
    HypercholesterolemiaDiagnose d casesb Males= 174, Females= 516Raised cholesterol levels on screening ≥5.2 mmol/LTotal prevalencec (N=2985) (both diagnosed & screened) Males=965, Females=2020
    Controlled <5.2 mmol/LUncontrolled ≥5.2 mmol/L
    Males98 (10.1)76 (7.9)315 (32.6)489 (50.7)
    Females236 (11.6)280 (13.9)***563 (27.9)1079 (53.4)
    Total334 (11.1)356 (11.9)878 (29.4)1568 (52.5)
    Body mass index‡Overweightb BMI ≥25.0 - ≤29.99Obesityb BMI ≥30Total prevalencec (N=2997) Males = 968, Females = 2029
    Male363 (37.5)399 (41.2)762 (78.7)
    Female587 (28.9)1149 (56.7)§1739 (85.7)
    Total950 (31.7)1548 (51.7)2504 (83.6)
    Waist circumferenceCentral obesityb Male >90 - <102 cms, Female >80 - <88 cmsHigh central obesityb Male >102cms, Female >88cmsTotal prevalencec (N=2997) Males = 968, Females = 2029
    Male256 (26.4)286 (29.5)542 (56)
    Female435 (21.4)‡1252 (61.7)†1687 (83.1)
    Total691 (23.0)1538 (51.3)2229 (74.4)
    • a Diagnosed cases were physician diagnosed and those identified on screened were identified on conducting blood tests, bRow percentage cColumn percentage, dMissing data: DM males=7 and females=28; High cholesterol males= 3 and females = 8; Hypertriglyceridemia males=12 and females=30, p-values calculated using the Chi square test, *Total prevalence of diabetes mellitus in females compared to males: odds ratio (95%CI)=1.30 (1.16, 1.56), p=0.006, **Uncontrolled cases of hypertension in females compared to males: odds ratio (95%CI) = 0.57 (0.39, 0.84), p=0.004, ***Uncontrolled cases of hypercholesterolemia in females compared to males: odds ratio (95%CI) = 1.60 (1.12, 2.25),p=0.008, §Prevalence of obesity (BMI ≥30) in females compared to males: odds ratio (95% CI) = 2.02 (1.63, 2.50), p<0.001, ‡Prevalence of central obesity in females compared to males: odds ratio (95% CI) = 2.12 (1.72, 2.61), p<0.001, †Prevalence of high central obesity in females compared to males: odds ratio (95% CI)= 5.45 (4.50, 6.60), p<0.001

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    Table 3

    - Proportion of Saudi men and women with high 10-year and lifetime atherosclerotic cardiovascular disease (ASCVD) risk scores by age category in Riyadh city, Saudi Arabia.

    ASCVD riskAge in years
    MalesFemalesTotal
    Ten year ASCVD riska (>7.5) males=324, females=640 (n=964)104 (32.1)49 (7.6)153 (15.9)*
    Age (years)
    40-496 (12.2)3 (6.1)40 (81.6)
    50-5935 (33.7)20 (19.2)49 (47.1)
    60-7541 (26.8)23 (15.0)89 (58.2)
    Odds ratio between gender and 10 year ASCVD risk scores5.70 (3.93, 8.28)
    Lifetime ASCVD riskb (>39%)males=639, females=1279 (n=1918)430 (67.3)651 (50.9)1081 (56.4)
    Age (years)
    30-39238 (36.6)284 (43.6)129 (19.8)
    40-49143 (33.3)226 (52.6)61 (14.2)
    50-59381 (35.2)510 (47.2)190 (17.6)
    Odds ratio between gender and lifetime ASCVD risk scores1.98 (1.63, 2.42)
    • Values are presented as number and percentage (%), P-values calculated using the Chi-square test;

    • ↵a ASCVD 10-years risk difference between gender and age p<0.001,

    • b ASCVD lifetime risk difference between gender and age p=0.007

    • View popup
    Table 4

    - Proportion of Saudi men and women with number of risk factors by age in Riyadh city, Saudi Arabia.

    Number of risk factors by age*GenderAge in categories n (%)Total (N=2032)Males=690 Females=1342
    30-3940-4950-5960-75
    1Males152 (59)59 (23)38 (15)8 (3)257 (40.3)
    Females352 (55)206 (32)71 (11)10 (2)639 (65.5)
    2Males127 (53)68 (28)30 (12)17 (7)242 (37.9)
    Females84 (36)80 (35)39 (17)28 (12)231 (23.7)
    3Males48 (42)38 (33)13 (11)16 (14)115 (18)
    Females9 (12)24 (31)32 (42)*12 (15)77 (7.9)
    4Males9 (37)6 (25)4 (17)5 (21)24 (3.8)
    Females1 (4)10 (36)8 (28)9 (32)28 (2.9)
    • ↵* Key for risk factors include age, gender, systolic blood pressure (at the time of the interview), treatment for hypertension (yes/no), diabetes (yes/no), smoking (yes/no), total blood cholesterol, high-density lipoprotein (HDL), 1: p=0.02, 2 p=0.004, 3: p<0.001, 4: p=0.02,

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Saudi Medical Journal: 42 (5)
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Age and gender differences in the prevalence of chronic diseases and atherosclerotic cardiovascular disease risk scores in adults in Riyadh city, Saudi Arabia
AlJohara M. AlQuaiz, Ambreen Kazi, Abdulaziz A. Alodhayani, Aljohara Almeneessier, Khaled M. AlHabeeb, Amna R. Siddiqui
Saudi Medical Journal May 2021, 42 (5) 526-536; DOI: 10.15537/smj.2021.42.5.20200684

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Age and gender differences in the prevalence of chronic diseases and atherosclerotic cardiovascular disease risk scores in adults in Riyadh city, Saudi Arabia
AlJohara M. AlQuaiz, Ambreen Kazi, Abdulaziz A. Alodhayani, Aljohara Almeneessier, Khaled M. AlHabeeb, Amna R. Siddiqui
Saudi Medical Journal May 2021, 42 (5) 526-536; DOI: 10.15537/smj.2021.42.5.20200684
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