Skip to main content

Main menu

  • Home
  • Content
    • Latest
    • Archive
    • home
  • Info for
    • Authors
    • Reviewers
    • Subscribers
    • Institutions
    • Advertisers
    • Join SMJ
  • About Us
    • About Us
    • Editorial Office
    • Editorial Board
  • More
    • Advertising
    • Alerts
    • Feedback
    • Folders
    • Help
  • Other Publications
    • NeuroSciences Journal

User menu

  • My alerts
  • Log in

Search

  • Advanced search
Saudi Medical Journal
  • Other Publications
    • NeuroSciences Journal
  • My alerts
  • Log in
Saudi Medical Journal

Advanced Search

  • Home
  • Content
    • Latest
    • Archive
    • home
  • Info for
    • Authors
    • Reviewers
    • Subscribers
    • Institutions
    • Advertisers
    • Join SMJ
  • About Us
    • About Us
    • Editorial Office
    • Editorial Board
  • More
    • Advertising
    • Alerts
    • Feedback
    • Folders
    • Help
  • Follow psmmc on Twitter
  • Visit psmmc on Facebook
  • RSS
Research ArticleOriginal Articles
Open Access

Childhood nephrolithiasis and nephrocalcinosis caused by metabolic diseases and renal tubulopathy

A retrospective study from 2 tertiary centers

Jameela A. Kari, Mohamed A. Shalaby, Faiza A. Qari, Amr S. Albanna and Khalid A. Alhasan
Saudi Medical Journal January 2022, 43 (1) 81-90; DOI: https://doi.org/10.15537/smj.2022.43.1.20210650
Jameela A. Kari
From the Department of Pediatrics (Kari, Shalaby), Pediatric Nephrology Center of Excellence; from the Department of Medicine (Qari), King Abdulaziz University, from King Abdullah International Medical Research Center (Albanna), King Saud Bin Abdulaziz University for Health Sciences, Jeddah, and from the Department of Pediatric (Alhasan), College of Medicine, King Saud University, Riyadh, Kingdom of Saudi Arabia.
MD, FRCP
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • For correspondence: [email protected]
Mohamed A. Shalaby
From the Department of Pediatrics (Kari, Shalaby), Pediatric Nephrology Center of Excellence; from the Department of Medicine (Qari), King Abdulaziz University, from King Abdullah International Medical Research Center (Albanna), King Saud Bin Abdulaziz University for Health Sciences, Jeddah, and from the Department of Pediatric (Alhasan), College of Medicine, King Saud University, Riyadh, Kingdom of Saudi Arabia.
MSc
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Faiza A. Qari
From the Department of Pediatrics (Kari, Shalaby), Pediatric Nephrology Center of Excellence; from the Department of Medicine (Qari), King Abdulaziz University, from King Abdullah International Medical Research Center (Albanna), King Saud Bin Abdulaziz University for Health Sciences, Jeddah, and from the Department of Pediatric (Alhasan), College of Medicine, King Saud University, Riyadh, Kingdom of Saudi Arabia.
MD
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Amr S. Albanna
From the Department of Pediatrics (Kari, Shalaby), Pediatric Nephrology Center of Excellence; from the Department of Medicine (Qari), King Abdulaziz University, from King Abdullah International Medical Research Center (Albanna), King Saud Bin Abdulaziz University for Health Sciences, Jeddah, and from the Department of Pediatric (Alhasan), College of Medicine, King Saud University, Riyadh, Kingdom of Saudi Arabia.
MD
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Khalid A. Alhasan
From the Department of Pediatrics (Kari, Shalaby), Pediatric Nephrology Center of Excellence; from the Department of Medicine (Qari), King Abdulaziz University, from King Abdullah International Medical Research Center (Albanna), King Saud Bin Abdulaziz University for Health Sciences, Jeddah, and from the Department of Pediatric (Alhasan), College of Medicine, King Saud University, Riyadh, Kingdom of Saudi Arabia.
MD
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • Article
  • Figures & Data
  • eLetters
  • Info & Metrics
  • References
  • PDF
Loading

References

  1. 1.↵
    1. Weigert A,
    2. Hoppe B.
    Nephrolithiasis and nephrocalcinosis in childhood-risk factor-related current and future treatment options. Front Pediatr 2018; 6: 98.
    OpenUrl
  2. 2.↵
    1. Magni G,
    2. Unwin RJ,
    3. Moochhala SH.
    Renal tubular acidosis (RTA) and kidney stones: diagnosis and management. Arch Esp Urol 2021; 74: 123–128.
    OpenUrl
  3. 3.↵
    1. Faller N,
    2. Dhayat NA,
    3. Fuster DG.
    Nephrolithiasis secondary to inherited defects in the thick ascending loop of henle and connecting tubules. Urolithiasis 2019; 47: 43–56.
    OpenUrl
  4. 4.↵
    1. Plain A,
    2. Alexander RT.
    Claudins and nephrolithiasis. Curr Opin Nephrol Hypertens 2018; 27: 268–276.
    OpenUrlPubMed
  5. 5.↵
    1. Ratkalkar VN,
    2. Kleinman JG.
    Mechanisms of stone formation. Clin Rev Bone Miner Metab 2011; 9: 187–197.
    OpenUrlPubMed
  6. 6.↵
    1. Edvardsson VO,
    2. Goldfarb DS,
    3. Lieske JC,
    4. Beara-Lasic L,
    5. Anglani F,
    6. Milliner DS, et al.
    Hereditary causes of kidney stones and chronic kidney disease. Pediatr Nephrol 2013; 28: 1923–1942.
    OpenUrlCrossRefPubMed
  7. 7.↵
    1. Hernandez JD,
    2. Ellison JS,
    3. Lendvay TS.
    Current trends, evaluation, and management of pediatric nephrolithiasis. JAMA Pediatr 2015; 169: 964–970.
    OpenUrl
  8. 8.↵
    1. Boyce AM,
    2. Shawker TH,
    3. Hill SC,
    4. Choyke PL,
    5. Hill MC,
    6. James R, et al.
    Ultrasound is superior to computed tomography for assessment of medullary nephrocalcinosis in hypoparathyroidism. J Clin Endocrinol Metab 2013; 98: 989–994.
    OpenUrlCrossRefPubMed
  9. 9.
    1. Matos V,
    2. van Melle G,
    3. Boulat O,
    4. Markert M,
    5. Bachmann C,
    6. Guignard JP.
    Urinary phosphate/creatinine, calcium/creatinine, and magnesium/creatinine ratios in a healthy pediatric population. J Pediatr 1997; 131: 252–257.
    OpenUrlCrossRefPubMedWeb of Science
  10. 10.↵
    1. Salvador CL,
    2. Tøndel C,
    3. Rowe AD,
    4. Bjerre A,
    5. Brun A,
    6. Brackman D, et al.
    Estimating glomerular filtration rate in children: evaluation of creatinine- and cystatin C-based equations. Pediatr Nephrol 2019; 34: 301–311.
    OpenUrl
  11. 11.↵
    1. Hoppe B,
    2. Martin-Higueras C.
    Inherited conditions resulting in nephrolithiasis. Curr Opin Pediatr 2020; 32: 273–283.
    OpenUrl
  12. 12.↵
    1. Braun DA,
    2. Lawson JA,
    3. Gee HY,
    4. Halbritter J,
    5. Shril S,
    6. Tan W, et al.
    Prevalence of monogenic causes in pediatric patients with nephrolithiasis or nephrocalcinosis. Clin J Am Soc Nephrol 2016; 11: 664–672.
    OpenUrlAbstract/FREE Full Text
  13. 13.↵
    1. Marzuillo P,
    2. Guarino S,
    3. Apicella A,
    4. La Manna A,
    5. Polito C.
    Why we need a higher suspicion index of urolithiasis in children. J Pediatr Urol 2017; 13: 164–171.
    OpenUrl
  14. 14.↵
    1. Tasian GE,
    2. Copelovitch L.
    Evaluation and medical management of kidney stones in children. J Urol 2014; 192: 1329–1336.
    OpenUrlCrossRefPubMed
  15. 15.↵
    1. Copelovitch L.
    Urolithiasis in children: medical approach. Pediatr Clin North Am 2012; 59: 881–896.
    OpenUrlPubMed
  16. 16.↵
    1. Kokorowski PJ,
    2. Hubert K,
    3. Nelson CP.
    Evaluation of pediatric nephrolithiasis. Indian J Urol 2010; 26: 531–535.
    OpenUrlPubMed
  17. 17.↵
    1. Daga A,
    2. Majmundar AJ,
    3. Braun DA,
    4. Gee HY,
    5. Lawson JA,
    6. Shril S, et al.
    Whole exome sequencing frequently detects a monogenic cause in early onset nephrolithiasis and nephrocalcinosis. Kidney Int 2018; 93: 204–213.
    OpenUrlCrossRefPubMed
  18. 18.↵
    1. Halbritter J,
    2. Baum M,
    3. Hynes AM,
    4. Rice SJ,
    5. Thwaites DT,
    6. Gucev ZS, et al.
    Fourteen monogenic genes account for 15% of nephrolithiasis/nephrocalcinosis. J Am Soc Nephrol 2015; 26: 543–551.
    OpenUrlAbstract/FREE Full Text
  19. 19.↵
    1. Alpay H,
    2. Ozen A,
    3. Gokce I,
    4. Biyikli N.
    Clinical and metabolic features of urolithiasis and microlithiasis in children. Pediatr Nephrol 2009; 24: 2203–2209.
    OpenUrlCrossRefPubMedWeb of Science
  20. 20.↵
    1. Cameron MA,
    2. Sakhaee K,
    3. Moe OW.
    Nephrolithiasis in children. Pediatr Nephrol 2005; 20: 1587–1592.
    OpenUrlCrossRefPubMedWeb of Science
  21. 21.↵
    1. Nicoletta JA,
    2. Lande MB.
    Medical evaluation and treatment of urolithiasis. Pediatr Clin North Am 2006; 53: 479–491.
    OpenUrlPubMed
  22. 22.↵
    1. Alghamdi M,
    2. Alhasan KA,
    3. Taha Elawad A,
    4. Salim S,
    5. Abdelhakim M,
    6. Nashabat M, et al.
    Diversity of phenotype and genetic etiology of 23 cystinuria Saudi patients: a retrospective study. Front Pediatr 2020; 8: 569389.
    OpenUrl
  23. 23.↵
    1. Hess B,
    2. Michel R,
    3. Takkinen R,
    4. Ackermann D,
    5. Jaeger P.
    Risk factors for low urinary citrate in calcium nephrolithiasis: low vegetable fibre intake and low urine volume to be added to the list. Nephrol Dial Transplant 1994; 9: 642–649.
    OpenUrlPubMedWeb of Science
  24. 24.↵
    1. Kari JA,
    2. Farouq M,
    3. Alshaya HO.
    Familial hypomagnesemia with hypercalciuria and nephrocalcinosis. Pediatr Nephrol 2003; 18: 506–510.
    OpenUrlPubMedWeb of Science
  25. 25.↵
    1. Konrad M,
    2. Hou J,
    3. Weber S,
    4. Dötsch J,
    5. Kari JA,
    6. Seeman T, et al.
    CLDN16 genotype predicts renal decline in familial hypomagnesemia with hypercalciuria and nephrocalcinosis. J Am Soc Nephrol 2008; 19: 171–181.
    OpenUrlFREE Full Text
  26. 26.↵
    National Center for Biotechnology Information. Hereditary distal renal tubular acidosis. [Updated 2019; 2021 Dec]. Available from: https://www.ncbi.nlm.nih.gov/books/NBK547595/
  27. 27.↵
    1. Lopez-Garcia SC,
    2. Emma F,
    3. Walsh SB,
    4. Fila M,
    5. Hooman N,
    6. Zaniew M, et al.
    Treatment and long-term outcome in primary distal renal tubular acidosis. Nephrol Dial Transplant 2019; 34: 981–991.
    OpenUrl
PreviousNext
Back to top

In this issue

Saudi Medical Journal: 43 (1)
Saudi Medical Journal
Vol. 43, Issue 1
1 Jan 2022
  • Table of Contents
  • Cover (PDF)
  • Index by author
Print
Download PDF
Email Article

Thank you for your interest in spreading the word on Saudi Medical Journal.

NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.

Enter multiple addresses on separate lines or separate them with commas.
Childhood nephrolithiasis and nephrocalcinosis caused by metabolic diseases and renal tubulopathy
(Your Name) has sent you a message from Saudi Medical Journal
(Your Name) thought you would like to see the Saudi Medical Journal web site.
Citation Tools
Childhood nephrolithiasis and nephrocalcinosis caused by metabolic diseases and renal tubulopathy
Jameela A. Kari, Mohamed A. Shalaby, Faiza A. Qari, Amr S. Albanna, Khalid A. Alhasan
Saudi Medical Journal Jan 2022, 43 (1) 81-90; DOI: 10.15537/smj.2022.43.1.20210650

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
Share
Childhood nephrolithiasis and nephrocalcinosis caused by metabolic diseases and renal tubulopathy
Jameela A. Kari, Mohamed A. Shalaby, Faiza A. Qari, Amr S. Albanna, Khalid A. Alhasan
Saudi Medical Journal Jan 2022, 43 (1) 81-90; DOI: 10.15537/smj.2022.43.1.20210650
Twitter logo Facebook logo Mendeley logo
  • Tweet Widget
  • Facebook Like
  • Google Plus One
Bookmark this article

Jump to section

  • Article
    • Abstract
    • Methods
    • Results
    • Discussion
    • Acknowledgment
    • Appendix 1 - Cut-off level (95th centile) of solute: creatine ratio in relation to age group.
    • Footnotes
    • References
  • Figures & Data
  • eLetters
  • References
  • Info & Metrics
  • PDF

Related Articles

  • No related articles found.
  • PubMed
  • Google Scholar

Cited By...

  • No citing articles found.
  • Google Scholar

More in this TOC Section

  • Trends and patterns in urgent pediatric otolaryngology inter-hospital referrals in Saudi Arabia
  • The effect of wet-cupping therapy (hijama) in modulating autoimmune activity of Hashimoto’s thyroiditis
  • Evaluation of hematological parameters in dyspepsia patients infected with Helicobacter pylori
Show more Original Articles

Similar Articles

Keywords

  • distal renal tubular acidosis
  • FHHNC
  • nephrolithiasis

CONTENT

  • home

JOURNAL

  • home

AUTHORS

  • home
Saudi Medical Journal

© 2025 Saudi Medical Journal Saudi Medical Journal is copyright under the Berne Convention and the International Copyright Convention.  Saudi Medical Journal is an Open Access journal and articles published are distributed under the terms of the Creative Commons Attribution-NonCommercial License (CC BY-NC). Readers may copy, distribute, and display the work for non-commercial purposes with the proper citation of the original work. Electronic ISSN 1658-3175. Print ISSN 0379-5284.

Powered by HighWire