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Research ArticleOriginal Article
Open Access

Prevalence and predictive factors for infertility-related stress among infertile couples

A cross-sectional study from Jordan and the occupied Palestinian territories

Deema J. Jaber, Haneen A. Basheer, Abla M. Albsoul-Younes, Lina M. Elsalem, Jehan M. Hamadneh, Mohammad K. Dweib and Hanadi T. Ahmedah
Saudi Medical Journal October 2022, 43 (10) 1149-1156; DOI: https://doi.org/10.15537/smj.2022.43.10.20220411
Deema J. Jaber
From the Department of Clinical Pharmacy (Jaber, Basheer), Faculty of Pharmacy, Zarqa University, Zarqa, from the Department of Clinical Pharmacy (Albsoul-Younes), University of Jordan, Amman, from the Department of Pharmacology (Elsalem); from the Department of Obstetrics and Gynecology (Hamadneh), Faculty of Medicine, Jordan University of Science and Technology, Irbid, Jordan, from the Department of Clinical Pharmacy (Dweib), Faculty of Pharmacy, Hebron University, Hebron, Palestine, and from the Department of Medical Laboratory Technology (Ahmedah), Faculty of Applied Medical Sciences, King Abdulaziz University, Rabigh, Kingdom of Saudi Arabia.
MSc, PhD
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  • For correspondence: [email protected]
Haneen A. Basheer
From the Department of Clinical Pharmacy (Jaber, Basheer), Faculty of Pharmacy, Zarqa University, Zarqa, from the Department of Clinical Pharmacy (Albsoul-Younes), University of Jordan, Amman, from the Department of Pharmacology (Elsalem); from the Department of Obstetrics and Gynecology (Hamadneh), Faculty of Medicine, Jordan University of Science and Technology, Irbid, Jordan, from the Department of Clinical Pharmacy (Dweib), Faculty of Pharmacy, Hebron University, Hebron, Palestine, and from the Department of Medical Laboratory Technology (Ahmedah), Faculty of Applied Medical Sciences, King Abdulaziz University, Rabigh, Kingdom of Saudi Arabia.
MSc, PhD
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Abla M. Albsoul-Younes
From the Department of Clinical Pharmacy (Jaber, Basheer), Faculty of Pharmacy, Zarqa University, Zarqa, from the Department of Clinical Pharmacy (Albsoul-Younes), University of Jordan, Amman, from the Department of Pharmacology (Elsalem); from the Department of Obstetrics and Gynecology (Hamadneh), Faculty of Medicine, Jordan University of Science and Technology, Irbid, Jordan, from the Department of Clinical Pharmacy (Dweib), Faculty of Pharmacy, Hebron University, Hebron, Palestine, and from the Department of Medical Laboratory Technology (Ahmedah), Faculty of Applied Medical Sciences, King Abdulaziz University, Rabigh, Kingdom of Saudi Arabia.
PhD
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Lina M. Elsalem
From the Department of Clinical Pharmacy (Jaber, Basheer), Faculty of Pharmacy, Zarqa University, Zarqa, from the Department of Clinical Pharmacy (Albsoul-Younes), University of Jordan, Amman, from the Department of Pharmacology (Elsalem); from the Department of Obstetrics and Gynecology (Hamadneh), Faculty of Medicine, Jordan University of Science and Technology, Irbid, Jordan, from the Department of Clinical Pharmacy (Dweib), Faculty of Pharmacy, Hebron University, Hebron, Palestine, and from the Department of Medical Laboratory Technology (Ahmedah), Faculty of Applied Medical Sciences, King Abdulaziz University, Rabigh, Kingdom of Saudi Arabia.
MSc, PhD
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Jehan M. Hamadneh
From the Department of Clinical Pharmacy (Jaber, Basheer), Faculty of Pharmacy, Zarqa University, Zarqa, from the Department of Clinical Pharmacy (Albsoul-Younes), University of Jordan, Amman, from the Department of Pharmacology (Elsalem); from the Department of Obstetrics and Gynecology (Hamadneh), Faculty of Medicine, Jordan University of Science and Technology, Irbid, Jordan, from the Department of Clinical Pharmacy (Dweib), Faculty of Pharmacy, Hebron University, Hebron, Palestine, and from the Department of Medical Laboratory Technology (Ahmedah), Faculty of Applied Medical Sciences, King Abdulaziz University, Rabigh, Kingdom of Saudi Arabia.
MD, PhD
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Mohammad K. Dweib
From the Department of Clinical Pharmacy (Jaber, Basheer), Faculty of Pharmacy, Zarqa University, Zarqa, from the Department of Clinical Pharmacy (Albsoul-Younes), University of Jordan, Amman, from the Department of Pharmacology (Elsalem); from the Department of Obstetrics and Gynecology (Hamadneh), Faculty of Medicine, Jordan University of Science and Technology, Irbid, Jordan, from the Department of Clinical Pharmacy (Dweib), Faculty of Pharmacy, Hebron University, Hebron, Palestine, and from the Department of Medical Laboratory Technology (Ahmedah), Faculty of Applied Medical Sciences, King Abdulaziz University, Rabigh, Kingdom of Saudi Arabia.
BSc, MSc
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Hanadi T. Ahmedah
From the Department of Clinical Pharmacy (Jaber, Basheer), Faculty of Pharmacy, Zarqa University, Zarqa, from the Department of Clinical Pharmacy (Albsoul-Younes), University of Jordan, Amman, from the Department of Pharmacology (Elsalem); from the Department of Obstetrics and Gynecology (Hamadneh), Faculty of Medicine, Jordan University of Science and Technology, Irbid, Jordan, from the Department of Clinical Pharmacy (Dweib), Faculty of Pharmacy, Hebron University, Hebron, Palestine, and from the Department of Medical Laboratory Technology (Ahmedah), Faculty of Applied Medical Sciences, King Abdulaziz University, Rabigh, Kingdom of Saudi Arabia.
MSc, PhD
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Article Figures & Data

Tables

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    Table 1

    - Socio-demographic characteristics of the study sample (N=443).

    Variablesn (%)
    Hospital
    JU132 (29.8)
    JUST183 (41.3)
    Occupied Palestinian territories’ centers128 (28.9)
    Gender
    Male180 (40.6)
    Female263 (59.4)
    Weight in kg, mean±SD
    Male80.5±15.2
    Female68.7±12.4
    Smoking
    Smoker106 (23.9)
    Non-smoker296 (66.8)
    Ex-smoker (more than 6 months)23 (5.2)
    Waterpipe17 (3.8)
    Insurance type
    MOH225 (50.8)
    Private99 (22.4)
    Others32 (7.2)
    Suffering from chronic diseases (hypertension, diabetes, heart diseases, respiratory problems, and others)
    Yes59 (13.3)
    No386 (87.1)
    Suffering from Vitamin D deficiency
    Yes102 (23.0)
    No318 (71.8)

    Values are presented as a number and precentage (%). Some data was missing, subsequently totals do not always add to 443.

    JU: Jordan University, JUST: Jordan University of Science and Technology, MOH: Ministry of Health, SD: standard deviation

      • View popup
      Table 2

      - Infertility characteristics of the study sample at baseline (N=443).

      Variablesn (%)
      Family type
      Nuclear239 (54.0)
      Extended200 (45.1)
      Period of seeking therapy for infertility in years, mean±SD4.2±4.1
      Presence of any close relative who suffers from infertility
      Yes56 (12.6)
      No386 (87.1)
      Number of IUI or IVF trials, mean±SD1.5±1.0
      Number of doctors who follow the case, mean±SD2.8±2.6
      Cost of infertility treatment per month in JD, mean±SD190±395
      The ART cost is covered by the insurance
      Yes115 (25.9)
      No328 (74.0)
      Seeking any psychological consultation for the infertility related stress
      Yes8 (1.8)
      No304 (68.6)

      Values are presented as a number and precentage (%). Some data was missing, subsequently totals do not always add to 443.

      SD: standard deviation, IUI: intrauterine insemination, IVF: in vitro fertilisation, JD: Jordanian dinar, ART: assisted reproductive technologies

        • View popup
        Table 3

        - Summary of different infertility-related stress scores (N=443).

        Infertility-related stress scoresTotal couplesMaleFemaleP-values
        Global stress152.4±21.5150.6±20.7153.7±22.10.14
        Areas of stress
        Social concern31.8±5.832.3±4.931.5±6.40.23
        Sexual concern27.1±6.527.1±6.127.1±6.80.92
        Relationship concern33.8±5.934.7±5.732.1±5.90.008*
        Rejection of child-free lifestyle25.7±6.625.1±6.626.1±6.50.117
        Need for parenthood36.1±8.034.8±7.437.1±8.30.005*

        Values are presented as mean ± standard deviation (SD).

        • ↵* Significant at less than 0.05 level.

        • View popup
        Table 4

        - Assessment of factors affecting global stress score among infertile couples (N=443).

        Independent variablesGlobal stress scores
        Simple linear regressionStepwise multiple linear regression
        Standardised Coefficients BetaP-valuesStandardised Coefficients BetaP-values
        Age-0.0300.584--
        Country (Jordan, occupied Palestinian territories)0.394<0.001*0.244<0.001*
        Gender (male, female)0.0370.477--
        Smoking (smoker, non-smoker, ex-smoker, waterpipe)0.0810.12--
        Family type (nuclear, extended)0.1430.006*0.1230.035*
        Education (illiterate, high school, BSc, or postgraduate)-0.0790.128--
        Working (yes, no)0.0390.460--
        Insurance (yes, no)0.1220.019*0.0830.161
        Whole monthly salary-0.0970.138--
        Period of marriage in years0.0310.552--
        Period of being without children in years0.0850.102--
        ARTs (ovulation induction medication, IVF, IUI, or more than one type)0.0120.829--
        Number of ART trials-0.1280.108--
        Number of doctors who follow up the case-0.1330.011*-0.1550.013*
        Cause of infertility (wife, husband, both wife and husband, or unknown cause)-0.1180.023*-0.1020.084
        Cost of ART per month in JD-0.0450.474--
        Total cost of ART0.1080.07--
        Presence of any relative suffering from infertility (yes, no)0.1090.037*0.1010.081
        Suffering from Vitamin D deficiency (yes, no)0.0880.099--
        • ↵* Significant at less than 0.05 level. BSc: Bachelor of Sciences, ARTs: assisted reproductive technologies, IVF: in vitro fertilisation, IUI: intrauterine insemination, JD: Jordanian dinar

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      Prevalence and predictive factors for infertility-related stress among infertile couples
      Deema J. Jaber, Haneen A. Basheer, Abla M. Albsoul-Younes, Lina M. Elsalem, Jehan M. Hamadneh, Mohammad K. Dweib, Hanadi T. Ahmedah
      Saudi Medical Journal Oct 2022, 43 (10) 1149-1156; DOI: 10.15537/smj.2022.43.10.20220411

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      Prevalence and predictive factors for infertility-related stress among infertile couples
      Deema J. Jaber, Haneen A. Basheer, Abla M. Albsoul-Younes, Lina M. Elsalem, Jehan M. Hamadneh, Mohammad K. Dweib, Hanadi T. Ahmedah
      Saudi Medical Journal Oct 2022, 43 (10) 1149-1156; DOI: 10.15537/smj.2022.43.10.20220411
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      Keywords

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