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Research ArticleOriginal Article
Open Access

Evaluation of the effects of berberine in the prevention of epidural fibrosis in rats

An experimental research

Emrah Keskin, Çağhan Tönge, Mustafa Kaya and Emre Işık
Saudi Medical Journal April 2022, 43 (4) 370-377; DOI: https://doi.org/10.15537/smj.2022.43.4.20210918
Emrah Keskin
From the Department of Neurosurgery (Keskin), Faculty of Medicine, Zonguldak Bülent Ecevit University, Zonguldak; from the Department of Neurosurgery (Tönge), University of Health Sciences, Gulhane School of Medicine, Diskapi Yildirim Beyazit Training and Research Hospital, Ankara; from the Department of Neurosurgery (Kaya), Sakarya University Education and Research Hospital, Sakarya; and from the Department of Pathology (Işık), Tunceli State Hospital, Tunceli, Turkey.
MD
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  • For correspondence: [email protected]
Çağhan Tönge
From the Department of Neurosurgery (Keskin), Faculty of Medicine, Zonguldak Bülent Ecevit University, Zonguldak; from the Department of Neurosurgery (Tönge), University of Health Sciences, Gulhane School of Medicine, Diskapi Yildirim Beyazit Training and Research Hospital, Ankara; from the Department of Neurosurgery (Kaya), Sakarya University Education and Research Hospital, Sakarya; and from the Department of Pathology (Işık), Tunceli State Hospital, Tunceli, Turkey.
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Mustafa Kaya
From the Department of Neurosurgery (Keskin), Faculty of Medicine, Zonguldak Bülent Ecevit University, Zonguldak; from the Department of Neurosurgery (Tönge), University of Health Sciences, Gulhane School of Medicine, Diskapi Yildirim Beyazit Training and Research Hospital, Ankara; from the Department of Neurosurgery (Kaya), Sakarya University Education and Research Hospital, Sakarya; and from the Department of Pathology (Işık), Tunceli State Hospital, Tunceli, Turkey.
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Emre Işık
From the Department of Neurosurgery (Keskin), Faculty of Medicine, Zonguldak Bülent Ecevit University, Zonguldak; from the Department of Neurosurgery (Tönge), University of Health Sciences, Gulhane School of Medicine, Diskapi Yildirim Beyazit Training and Research Hospital, Ankara; from the Department of Neurosurgery (Kaya), Sakarya University Education and Research Hospital, Sakarya; and from the Department of Pathology (Işık), Tunceli State Hospital, Tunceli, Turkey.
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Article Information

vol. 43 no. 4 370-377
DOI 
https://doi.org/10.15537/smj.2022.43.4.20210918
PubMed 
35414615

Published By 
Saudi Medical Journal
Online ISSN 
1658-3175
History 
  • Received February 18, 2022
  • Accepted March 21, 2022
  • Published online April 12, 2022.

Copyright & Usage 
Copyright: © Saudi Medical Journal This is an Open Access journal and articles published are distributed under the terms of the Creative Commons Attribution-NonCommercial License (CC BY-NC). Readers may copy, distribute, and display the work for non-commercial purposes with the proper citation of the original work.

Author Information

  1. Emrah Keskin, MD⇑,
  2. Çağhan Tönge, MD,
  3. Mustafa Kaya, MD and
  4. Emre Işık, MD
  1. From the Department of Neurosurgery (Keskin), Faculty of Medicine, Zonguldak Bülent Ecevit University, Zonguldak; from the Department of Neurosurgery (Tönge), University of Health Sciences, Gulhane School of Medicine, Diskapi Yildirim Beyazit Training and Research Hospital, Ankara; from the Department of Neurosurgery (Kaya), Sakarya University Education and Research Hospital, Sakarya; and from the Department of Pathology (Işık), Tunceli State Hospital, Tunceli, Turkey.
  1. Address correspondence and reprint request to: Dr. Emrah Keskin, Assistant Professor of Neurosurgery, Department of Neurosurgery, Faculty of Medicine, Zonguldak Bülent Ecevit University, Zonguldak, Turkey. E-mail: drkeskinemrah{at}gmail.com ORCID ID: https://orcid.org/0000-0001-5326-741X
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  • Platelet-rich fibrin and silver nano-particles loaded chitosan treatment for post- laminectomy epidural scar adhesions: in vivo rats study model
    Samah Fouad, Awad Rizk, Esam Mosbah, Mostafa M. Nabeeh, Walaa Awadin, Ayman S. Elmezayyen, Ekramy Elmorsy, Adel Zaghloul
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Evaluation of the effects of berberine in the prevention of epidural fibrosis in rats
Emrah Keskin, Çağhan Tönge, Mustafa Kaya, Emre Işık
Saudi Medical Journal Apr 2022, 43 (4) 370-377; DOI: 10.15537/smj.2022.43.4.20210918

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Evaluation of the effects of berberine in the prevention of epidural fibrosis in rats
Emrah Keskin, Çağhan Tönge, Mustafa Kaya, Emre Işık
Saudi Medical Journal Apr 2022, 43 (4) 370-377; DOI: 10.15537/smj.2022.43.4.20210918
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Keywords

  • berberine
  • epidural fibrosis
  • laminectomy

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© 2025 Saudi Medical Journal Saudi Medical Journal is copyright under the Berne Convention and the International Copyright Convention.  Saudi Medical Journal is an Open Access journal and articles published are distributed under the terms of the Creative Commons Attribution-NonCommercial License (CC BY-NC). Readers may copy, distribute, and display the work for non-commercial purposes with the proper citation of the original work. Electronic ISSN 1658-3175. Print ISSN 0379-5284.

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