Clinical and ultrasonographic features in cancer risk stratification of indeterminate thyroid nodules

Article Figures & Data

Table 1

- Patient demographics and ultrasound-based morphologic features of thyroid nodules (N=50).

Variable	Distribution
Gender
Male	8 (16.0)
Female	42 (84.0)
Age (years)	46.26±2.08
Pathology
Benign	31 (62.0)
Malignant	19 (38.0)
Biopsy method
US-guided	24 (48.0)
Non-US-guided	26 (52.0)
Composition
Mixed cystic and solid	15 (30.0)
Solid	35 (70.0)
Echogenicity
Hyperechoic or isoechoic	23 (46.0)
Hypoechoic	27 (54.0)
Shape
Wider-than-tall	50 (100)
Margin
Ill-defined	3 (6.0)
Smooth	47 (94.0)
Echogenic foci
Punctate echogenic foci	6 (12.0)
Macrocalcifications	4 (8.0)
None	40 (80.0)
Thyroid Imaging Reporting and Data System
TR2	6 (12.0)
TR3	23 (46.0)
TR4	17 (34.0)
TR5	4 (8.0)

Distribution reported as frequency (%), except for age, which is reported as mean±standard error of the mean. US: ultrasound

Table 2

- Association between different categories of Bethesda and TI-RADS classification system with the final pathology.

Pathology	TI-RADS	Bethesda category, n (%)		Significance
Pathology	TI-RADS	III	IV	P-value
Benign	TR2	1 (25.0)	3 (75.0)	0.039*
	TR3	11 (78.6)	3 (21.4)
	TR4	4 (36.4)	7 (63.6)
	TR5	0 (0.00)	2 (100)
Malignant	TR2	1 (50.0)	1 (50.0)	0.739
	TR3	6 (66.7)	3 (33.3)
	TR4	4 (66.7)	2 (33.3)
	TR5	2 (100)	0 (0.0)

* Statistically significant at p<0.05. TI-RADS: Thyroid Imaging Reporting and Data System

Table 3

- Association between various parameters and pathology (N=50).