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Research ArticleOriginal Article
Open Access

Application of arterial infusion ports in hepatic arterial infusion chemotherapy and embolization for advanced hepatocellular carcinoma

Xinqiang Han, Peng Zhao, Xuemin Wang, Xiaoyu Tan and Yongzhen Zhang
Saudi Medical Journal December 2023, 44 (12) 1283-1289; DOI: https://doi.org/10.15537/smj.2023.44.12.20230147
Xinqiang Han
From the Department of Interventional Medicine and Vascular Surgery (Han, Zhang), from the Department of Gastroenterology (Wang), and from the First Clinical Medical College (Tan), Binzhou Medical University Hospital; from the Department of Minimally Invasive (Zhao), Interventional Therapy Center, Qingdao Municipal Hospital, Shandong, China.
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Peng Zhao
From the Department of Interventional Medicine and Vascular Surgery (Han, Zhang), from the Department of Gastroenterology (Wang), and from the First Clinical Medical College (Tan), Binzhou Medical University Hospital; from the Department of Minimally Invasive (Zhao), Interventional Therapy Center, Qingdao Municipal Hospital, Shandong, China.
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Xuemin Wang
From the Department of Interventional Medicine and Vascular Surgery (Han, Zhang), from the Department of Gastroenterology (Wang), and from the First Clinical Medical College (Tan), Binzhou Medical University Hospital; from the Department of Minimally Invasive (Zhao), Interventional Therapy Center, Qingdao Municipal Hospital, Shandong, China.
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Xiaoyu Tan
From the Department of Interventional Medicine and Vascular Surgery (Han, Zhang), from the Department of Gastroenterology (Wang), and from the First Clinical Medical College (Tan), Binzhou Medical University Hospital; from the Department of Minimally Invasive (Zhao), Interventional Therapy Center, Qingdao Municipal Hospital, Shandong, China.
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Yongzhen Zhang
From the Department of Interventional Medicine and Vascular Surgery (Han, Zhang), from the Department of Gastroenterology (Wang), and from the First Clinical Medical College (Tan), Binzhou Medical University Hospital; from the Department of Minimally Invasive (Zhao), Interventional Therapy Center, Qingdao Municipal Hospital, Shandong, China.
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  • For correspondence: [email protected]
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  • Figure 1
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    Figure 1

    - An intraoperative arteriography. A) Angiography via implanted port (white arrow) showing no contrast agent leakage. B) Angiography via implanted port was performed to ensure that the tip of the catheter was located in the trunk of the tumor-supplying artery (white arrow).

  • Figure 2
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    Figure 2

    - The indwelling hepatic artery catheter is retracted from the proper hepatic artery to the initial segment of the gastroduodenal artery (white arrow).

Tables

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    Table 1

    - Comparison of general data and average medical costs.

    ParameterGroup A (n=69)Group B (n=47)Statistic valuesP-value
    Gender, n (%)  χ2=0.420.52
    Male38 (55.0)23 (49.0)  
    Female31 (45.0)24 (51.0)  
    Age / year52.83±11.4754.43±11.23t=-0.740.46
    Child-Pugh classify, n (%)  χ2=0.130.72
    A30 (43.0)22 (47.0)  
    B39 (57.0)25 (53.0)  
    Interruption of HAIC7(10.14)4 (8.5)--
    Hospitalization costs: (10,000 yuan/treatment period)0.54±0.241.04±0.19t= -151.43<0.01

    HAIC: hepatic arterial infusion chemotherapy

      • View popup
      Table 2

      - Comparison of general comfort questionnaire subscale.

      GroupPhysiology (20 points)Psychology (40 points)Social Culture (32 points)Environment (28 points)Totalize (120 points)
      Group A, (n=69)13.07±1.9824.42±3.2421.94±2.4217.25±2.4676.68±5.65
      Group B, (n=47)11.13±2.2921.40±3.1922.17±2.3917.57±2.4772.28±5.18
      T-value4.874.960.500.704.26
      P-value0.0000040.0000030.620.480.000042
      • View popup
      Table 3

      - Comparison of adverse reactions and complications.

      GroupsBellyacheAbdominal distentionHiccupHematomaArterial dissectionDVT*Gastric ulcer
      Group A (n=69)12 (14.7)7 (14.9)5 (7.2)0001 (1.4)
      Group B (n=47)9 (19.1)14 (20.3)4 (8.5)4 (8.5)1 (2.1)4 (8.5)0
      χ²-value0.067.280.06----
      P-value0.810.0070.80.030.410.031.00

      Values are presented as number and percentages (%).

      • ↵* DVT: deep vein thrombosis

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    Saudi Medical Journal: 44 (12)
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    1 Dec 2023
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    Application of arterial infusion ports in hepatic arterial infusion chemotherapy and embolization for advanced hepatocellular carcinoma
    Xinqiang Han, Peng Zhao, Xuemin Wang, Xiaoyu Tan, Yongzhen Zhang
    Saudi Medical Journal Dec 2023, 44 (12) 1283-1289; DOI: 10.15537/smj.2023.44.12.20230147

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    Application of arterial infusion ports in hepatic arterial infusion chemotherapy and embolization for advanced hepatocellular carcinoma
    Xinqiang Han, Peng Zhao, Xuemin Wang, Xiaoyu Tan, Yongzhen Zhang
    Saudi Medical Journal Dec 2023, 44 (12) 1283-1289; DOI: 10.15537/smj.2023.44.12.20230147
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    Keywords

    • hepatocellular carcinoma
    • hepatic arterial infusion chemotherapy
    • arterial catheterization
    • implantable arterial infusion port

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