Skip to main content

Main menu

  • Home
  • Content
    • Latest
    • Archive
    • home
  • Info for
    • Authors
    • Reviewers
    • Subscribers
    • Institutions
    • Advertisers
    • Join SMJ
  • About Us
    • About Us
    • Editorial Office
    • Editorial Board
  • More
    • Advertising
    • Alerts
    • Feedback
    • Folders
    • Help
  • Other Publications
    • NeuroSciences Journal

User menu

  • My alerts
  • Log in

Search

  • Advanced search
Saudi Medical Journal
  • Other Publications
    • NeuroSciences Journal
  • My alerts
  • Log in
Saudi Medical Journal

Advanced Search

  • Home
  • Content
    • Latest
    • Archive
    • home
  • Info for
    • Authors
    • Reviewers
    • Subscribers
    • Institutions
    • Advertisers
    • Join SMJ
  • About Us
    • About Us
    • Editorial Office
    • Editorial Board
  • More
    • Advertising
    • Alerts
    • Feedback
    • Folders
    • Help
  • Follow psmmc on Twitter
  • Visit psmmc on Facebook
  • RSS
Research ArticleOriginal Article
Open Access

The interaction between no folic acid supplementation during early pregnancy and preeclampsia increased the risk of preterm birth

Yi-Jie Zhang, Hong Jiang, Chengqiu Lu, Yi Sun, Shudong Cui and Chao Chen
Saudi Medical Journal March 2023, 44 (3) 260-267; DOI: https://doi.org/10.15537/smj.2023.44.3.20220695
Yi-Jie Zhang
From the Department of Neonatology (Zhang, Jiang), Affiliated Hospital of Qingdao University, Qingdao; from the Department of Neonatology (Chen), Children’s Hospital of Fudan University; from the Division of Neonatology (Lu), Gynecology and Obstetrics Hospital of Fudan University, Shanghai; from the Department of Neonatology (Sun), The Second Affiliated Hospital of Guangzhou Medical University, Guangzhou; from the Department of Neonatology (Cui), First Affiliated Hospital Nanjing Medical University, Nanjing, Chin.
MD, PhD
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • For correspondence: [email protected]
Hong Jiang
From the Department of Neonatology (Zhang, Jiang), Affiliated Hospital of Qingdao University, Qingdao; from the Department of Neonatology (Chen), Children’s Hospital of Fudan University; from the Division of Neonatology (Lu), Gynecology and Obstetrics Hospital of Fudan University, Shanghai; from the Department of Neonatology (Sun), The Second Affiliated Hospital of Guangzhou Medical University, Guangzhou; from the Department of Neonatology (Cui), First Affiliated Hospital Nanjing Medical University, Nanjing, Chin.
MD, PhD
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Chengqiu Lu
From the Department of Neonatology (Zhang, Jiang), Affiliated Hospital of Qingdao University, Qingdao; from the Department of Neonatology (Chen), Children’s Hospital of Fudan University; from the Division of Neonatology (Lu), Gynecology and Obstetrics Hospital of Fudan University, Shanghai; from the Department of Neonatology (Sun), The Second Affiliated Hospital of Guangzhou Medical University, Guangzhou; from the Department of Neonatology (Cui), First Affiliated Hospital Nanjing Medical University, Nanjing, Chin.
MD, PhD
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Yi Sun
From the Department of Neonatology (Zhang, Jiang), Affiliated Hospital of Qingdao University, Qingdao; from the Department of Neonatology (Chen), Children’s Hospital of Fudan University; from the Division of Neonatology (Lu), Gynecology and Obstetrics Hospital of Fudan University, Shanghai; from the Department of Neonatology (Sun), The Second Affiliated Hospital of Guangzhou Medical University, Guangzhou; from the Department of Neonatology (Cui), First Affiliated Hospital Nanjing Medical University, Nanjing, Chin.
MD, PhD
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Shudong Cui
From the Department of Neonatology (Zhang, Jiang), Affiliated Hospital of Qingdao University, Qingdao; from the Department of Neonatology (Chen), Children’s Hospital of Fudan University; from the Division of Neonatology (Lu), Gynecology and Obstetrics Hospital of Fudan University, Shanghai; from the Department of Neonatology (Sun), The Second Affiliated Hospital of Guangzhou Medical University, Guangzhou; from the Department of Neonatology (Cui), First Affiliated Hospital Nanjing Medical University, Nanjing, Chin.
MD, PhD
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Chao Chen
From the Department of Neonatology (Zhang, Jiang), Affiliated Hospital of Qingdao University, Qingdao; from the Department of Neonatology (Chen), Children’s Hospital of Fudan University; from the Division of Neonatology (Lu), Gynecology and Obstetrics Hospital of Fudan University, Shanghai; from the Department of Neonatology (Sun), The Second Affiliated Hospital of Guangzhou Medical University, Guangzhou; from the Department of Neonatology (Cui), First Affiliated Hospital Nanjing Medical University, Nanjing, Chin.
MD, PhD
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • Article
  • Figures & Data
  • eLetters
  • Info & Metrics
  • References
  • PDF
Loading

References

  1. 1.↵
    1. Goldenberg RL,
    2. Culhane JF,
    3. Iams JD,
    4. Romero R.
    Epidemiology and causes of preterm birth. Lancet 2008; 371: 75–84.
    OpenUrlCrossRefPubMedWeb of Science
  2. 2.↵
    1. Lawn JE,
    2. Cousens S,
    3. Zupan J.
    4 million neonatal deaths: when? Where? Why? Lancet 2005; 365: 891–900.
    OpenUrl
  3. 3.↵
    1. Liu L,
    2. Oza S,
    3. Hogan D,
    4. Chu Y,
    5. Perin J,
    6. Zhu J, et al.
    Global, regional, and national causes of under-5 mortality in 2000-15: an updated systematic analysis with implications for the Sustainable Development Goals. Lancet 2016; 388: 3027–3035.
    OpenUrlCrossRefPubMed
  4. 4.↵
    1. Wu Y,
    2. Yuan Y,
    3. Kong C,
    4. Ma Q,
    5. Ye H,
    6. Jing W, et al.
    The association between periconceptional folic acid supplementation and the risk of preterm birth: a population-based retrospective cohort study of 200,000 women in China. Eur J Nutr 2021; 60: 2181–2192.
    OpenUrl
  5. 5.
    1. Liu X,
    2. Lv L,
    3. Zhang H,
    4. Zhao N,
    5. Qiu J,
    6. He X, et al.
    Folic acid supplementation, dietary folate intake, and risk of preterm birth in China. Eur J Nutr 2016; 55: 1411–1422.
    OpenUrl
  6. 6.
    1. Sharif ME,
    2. Mohamedain A,
    3. Ahmed AA,
    4. Nasr AM,
    5. Adam I.
    Folic acid level and preterm birth among Sudanese women. Matern Health Neonatol Perinatol 2017; 3: 25.
    OpenUrl
  7. 7.↵
    1. Li B,
    2. Zhang X,
    3. Peng X,
    4. Zhang S,
    5. Wang X,
    6. Zhu C.
    Folic Acid and risk of preterm birth: a meta-analysis. Front Neurosci 2019; 13: 1284.
    OpenUrl
  8. 8.↵
    1. Min Jiang, Miskatul Mustafa Mishu,
    2. Dan Lu,
    3. Xianghua Yin
    . A case control study of risk factors and neonatal outcomes of preterm birth. Taiwan J Obstet Gynecol 2018; 57: 814–818.
    OpenUrl
  9. 9.↵
    1. Gejo NG,
    2. MT WM,
    3. Kebede BA,
    4. Abdo RA,
    5. Anshebo AA,
    6. Halil HM, et al.
    Factors associated with preterm birth at Wachemo University Nigist Eleni Mohammed memorial hospital, southern Ethiopia: case-control study. BMC Pregnancy Childbirth 2021; 21: 35.
    OpenUrl
  10. 10.↵
    1. Knol MJ
    , VanderWeele TJ, Groenwold RHH, Klungel OH, Rovers MM, Grobbee DE. Estimating measures of interaction on an additive scale for preventive exposures. Eur J Epidemiol 2011; 26: 433–438.
    OpenUrlCrossRefPubMed
  11. 11.↵
    1. Zhang YJ,
    2. Shen J,
    3. Lin SB,
    4. Lu C,
    5. Jiang H,
    6. Sun Y, et al.
    The risk factors of preterm birth: A multicentre case-control survey in China in 2018. J Paediatr Child Health 2022; 58: 1396–1406.
    OpenUrl
  12. 12.↵
    1. Xie X,
    2. Kong B,
    3. Duan T.
    Obstetrics and gynecology. 9th ed. Beijing: People’s Medical Publishing House. 2018.
  13. 13.↵
    Hypertensive Disorders in Pregnancy Subgroup, Chinese Society of Obstetrics and Gynecology, Chinese Medical Association; Hypertensive Disorders in Pregnancy Subgroup Chinese Society of Obstetrics and Gynecology Chinese Medical Association. [Diagnosis and treatment of hypertension and pre-eclampsia in pregnancy: a clinical practice guideline in China (2020)]. Zhonghua Fu Chan Ke Za Zhi 2020; 55: 227–238.
    OpenUrl
  14. 14.↵
    1. Obstetrics Subgroup
    , Chinese Society of Obstetrics and Gynecology, Chinese Medical Association; Group of Pregnancy with Diabetes Mellitus, Chinese Society of Perinatal Medicine, Chinese Medical Association, et al. [Diagnosis and therapy guideline of pregnancy with diabetes mellitus]. Zhonghua Fu Chan Ke Za Zhi 2014; 49:561–569. [in Chinese]
    OpenUrl
  15. 15.↵
    World Health Organization. Guidelines for controlling and monitoring the tobacco epidemic. [Updated 1998]. Available from: https://apps.who.int/iris/handle/10665/42049
  16. 16.↵
    1. Chen C,
    2. Lu FC
    , Department of Disease Control Ministry of Health, PR China. Guidelines for prevention and control of overweight and obesity in Chinese adults (excerpt). Biomed Environ Sci 2004; 25: 1–4.
    OpenUrl
  17. 17.↵
    1. Chuce Dai, Yiming Fei,
    2. Jianming Li, Yang Shi,
    3. Xiuhua Yang
    . A novel review of homocysteine and pregnancy complications. Biomed Res Int 2021; 2021: 6652231.
    OpenUrl
  18. 18.↵
    1. Weronika Dymara-Konopka,
    2. Marzena Laskowska
    . The role of nitric oxide, ADMA, and homocysteine in The etiopathogenesis of preeclampsia-review. Int J Mol Sci 2019; 20: 2757.
    OpenUrl
  19. 19.↵
    1. Mekuriyaw AM,
    2. Mihret MS,
    3. Yismaw AE.
    Determinants of preterm birth among women who gave birth in Amhara Region Referral hospitals, Northern Ethiopia, 2018: institutional based case control study. Int J Pediatr 2020; 2020: 1854073.
  20. 20.↵
    1. E L,
    2. Zhang C,
    3. Wang G,
    4. Ma Z
    . Investigation on the incidence, risk factors and pregnancy outcomes of pregnancy-induced hypertension in Xining area from 2007-2016. Matern Child Health J 2018; 33: 642–644. [in Chinese]
    OpenUrl
  21. 21.↵
    1. Deng L,
    2. Fang B.
    Clinical epidemiological analysis of pregnancy-induced hypertension. Hainan Medical Journal 2015; 26: 2602–2603. [in Chinese]
    OpenUrl
  22. 22.↵
    1. Shao Y,
    2. Qiu W,
    3. Mao B,
    4. Li Y,
    5. Zhou M,
    6. Yang L, et al.
    Correlation between folic acid intake before and during pregnancy and preterm birth. Matern Child Health J 2017; 32: 575–578. [in Chinese]
    OpenUrl
PreviousNext
Back to top

In this issue

Saudi Medical Journal: 44 (3)
Saudi Medical Journal
Vol. 44, Issue 3
1 Mar 2023
  • Table of Contents
  • Cover (PDF)
  • Index by author
Print
Download PDF
Email Article

Thank you for your interest in spreading the word on Saudi Medical Journal.

NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.

Enter multiple addresses on separate lines or separate them with commas.
The interaction between no folic acid supplementation during early pregnancy and preeclampsia increased the risk of preterm birth
(Your Name) has sent you a message from Saudi Medical Journal
(Your Name) thought you would like to see the Saudi Medical Journal web site.
Citation Tools
The interaction between no folic acid supplementation during early pregnancy and preeclampsia increased the risk of preterm birth
Yi-Jie Zhang, Hong Jiang, Chengqiu Lu, Yi Sun, Shudong Cui, Chao Chen
Saudi Medical Journal Mar 2023, 44 (3) 260-267; DOI: 10.15537/smj.2023.44.3.20220695

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
Share
The interaction between no folic acid supplementation during early pregnancy and preeclampsia increased the risk of preterm birth
Yi-Jie Zhang, Hong Jiang, Chengqiu Lu, Yi Sun, Shudong Cui, Chao Chen
Saudi Medical Journal Mar 2023, 44 (3) 260-267; DOI: 10.15537/smj.2023.44.3.20220695
Twitter logo Facebook logo Mendeley logo
  • Tweet Widget
  • Facebook Like
  • Google Plus One
Bookmark this article

Jump to section

  • Article
    • Abstract
    • Methods
    • Results
    • Discussion
    • Acknowledgment
    • Footnotes
    • References
  • Figures & Data
  • eLetters
  • References
  • Info & Metrics
  • PDF

Related Articles

  • No related articles found.
  • PubMed
  • Google Scholar

Cited By...

  • No citing articles found.
  • Google Scholar

More in this TOC Section

  • Prolonged flight exposure and its effects on sinonasal health among aircrew members
  • Identifying individuals at risk of post-stroke depression
  • Hematological parameters in recent and past dengue infections in Jazan Province, Saudi Arabia
Show more Original Article

Similar Articles

Keywords

  • preterm birth
  • folic acid supplementation
  • preeclampsia
  • interaction
  • risk factor

CONTENT

  • home

JOURNAL

  • home

AUTHORS

  • home
Saudi Medical Journal

© 2025 Saudi Medical Journal Saudi Medical Journal is copyright under the Berne Convention and the International Copyright Convention.  Saudi Medical Journal is an Open Access journal and articles published are distributed under the terms of the Creative Commons Attribution-NonCommercial License (CC BY-NC). Readers may copy, distribute, and display the work for non-commercial purposes with the proper citation of the original work. Electronic ISSN 1658-3175. Print ISSN 0379-5284.

Powered by HighWire