Research ArticleOriginal Article
Open Access

Metabolic and renal outcomes of empagliflozin in patients with type 2 diabetes mellitus attending Armed Forces Hospital in Saudi Arabia

Retrospective cohort study

Ali A. Alshahrani, Saad S. Al Qahtani, Abrar S. Al Qahtani, Saeed M. Mashhour, Zayed S. Alkhtani and Yahya M. Alragea
Saudi Medical Journal July 2023, 44 (7) 674-678; DOI: https://doi.org/10.15537/smj.2023.44.7.20230094

Article Figures & Data

Tables

  • Table 1

    - Age and gender distribution of the participants (N=308).

    VariablesDescription
    Gender, n (%)
    Male198 (64.3)
    Female110 (35.7)
    Age (years)23-89
    Range, mean±SD58.0±10.6

    • SD: standard deviation

  • Table 2

    - Comparison of metabolic and renal outcomes of empagliflozin in patients with T2DM at different follow-up periods.

    VariablesBefore starting empagliflozin Mean±SD3 weeks to 1 month after starting empagliflozin Mean±SD (p-value)3-5 months after starting empagliflozin Mean±SD (p-value)>6 months after starting empagliflozin Mean±SD (p-value)
    Weight (kg)83.3±15.9 (n=45)80.4 ±15.5 (0.010)  
    84.9±15.1 (n=152) 82.0±15.7 (<0.001) 
    83.4±13.9 (n=117)  79.4±12.8 (<0.001)
    LDL2.31±0.58 (n=19)2.23±0.63 (0.618)  
    2.53±0.91 (n=166) 2.36±0.84 (0.011) 
    2.55±0.77 (n=73)  2.60±0.87 (0.584)
    TG2.11±1.20 (n=33)1.88±1.18 (0.115)  
    1.79±0.96 (n=236) 1.77±1.08 (0.766) 
    1.87±0.99 (n=126)  1.77±0.80 (0.223)
    Creatinine83.79±30.14 (n=31)87.45±31.78 (0.105)  
    77.55±25.18 (n=227) 79.62±28.60 (0.059) 
    76.04±23.46 (n=147)  78.39±27.43 (0.033)
    UACR52.39±92.85 (n=21)32.87±44.34 (0.208)  
    123.86±348.6 (n=181) 91.87±226.3 (0.043) 
    133.41±391.8 (n=106)  71.92±169.3 (0.022)
    HbA1c8.93±1.50 (n=34)8.73±1.43 (0.411)  
    9.01±1.72 (n=260) 8.51±1.43 (<0.001) 
    8.85±1.55 (n=166)  8.34±1.35 (<0.001)
    SBP130.45±14.87 (n=22)129.59±11.63 (0.777)  
    129.35±13.77 (n=115) 129.05±12.71 (0.821) 
    129.52±13.06 (n=83)  126.04±12.33 (0.045)
    DBP75.09±8.62(n=22)72.41±7.79 (0.066)  
    74.26±8.32 (n=115) 73.20±7.35 (0.221) 
    75.19±7.92 (n=83)  71.61±8.95 (0.002)

    • T2DM: type 2 diabetes mellitus, SD: standard deviation, N: number of individuals with an event, LDL: low-density lipoprotein, TG: triglycerides, UACR: urine albumin-to-creatinine ratio, HBA1c: glycosylated hemoglobin, SBP: systolic blood pressure, DBP: diastolic blood pressure

Back to top

In this issue

Print
Download PDF
Email Article
Citation Tools
Bookmark this article

Jump to section

Keywords