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Research ArticleOriginal Article
Open Access

Association between body mass index and hemoglobin A1c with serum prostate-specific antigen level

A retrospective cohort study

Wejdan A. Alhamdan, Thamer A. Alsulaiman, Razan I. Alsabti, Ola M. Abdulmowla, Somayh E. Elnaggar and Yaser Alendijani
Saudi Medical Journal September 2023, 44 (9) 870-874; DOI: https://doi.org/10.15537/smj.2023.44.9.20230384
Wejdan A. Alhamdan
From the Department of Family Medicine and Polyclinics (Alhamdan, Alsulaiman, Alsabti, Alendijani), King Faisal Specialist Hospital and Research Center, and from the College of Medicine (Abdulmowla, Elnaggar), Al Faisal University, Riyadh, Kingdom of Saudi Arabia
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Thamer A. Alsulaiman
From the Department of Family Medicine and Polyclinics (Alhamdan, Alsulaiman, Alsabti, Alendijani), King Faisal Specialist Hospital and Research Center, and from the College of Medicine (Abdulmowla, Elnaggar), Al Faisal University, Riyadh, Kingdom of Saudi Arabia
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  • ORCID record for Thamer A. Alsulaiman
  • For correspondence: [email protected]
Razan I. Alsabti
From the Department of Family Medicine and Polyclinics (Alhamdan, Alsulaiman, Alsabti, Alendijani), King Faisal Specialist Hospital and Research Center, and from the College of Medicine (Abdulmowla, Elnaggar), Al Faisal University, Riyadh, Kingdom of Saudi Arabia
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Ola M. Abdulmowla
From the Department of Family Medicine and Polyclinics (Alhamdan, Alsulaiman, Alsabti, Alendijani), King Faisal Specialist Hospital and Research Center, and from the College of Medicine (Abdulmowla, Elnaggar), Al Faisal University, Riyadh, Kingdom of Saudi Arabia
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Somayh E. Elnaggar
From the Department of Family Medicine and Polyclinics (Alhamdan, Alsulaiman, Alsabti, Alendijani), King Faisal Specialist Hospital and Research Center, and from the College of Medicine (Abdulmowla, Elnaggar), Al Faisal University, Riyadh, Kingdom of Saudi Arabia
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Yaser Alendijani
From the Department of Family Medicine and Polyclinics (Alhamdan, Alsulaiman, Alsabti, Alendijani), King Faisal Specialist Hospital and Research Center, and from the College of Medicine (Abdulmowla, Elnaggar), Al Faisal University, Riyadh, Kingdom of Saudi Arabia
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    Figure 1

    - Frequency of medications used among participants.

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    Table 1

    - General characteristics of participants (N=750).

    Variablesn (%)
    Age, mean±SD61.36±10.82
    <402 (0.3)
    40-4995 (12.7)
    50-59245 (32.7)
    60-69238 (31.7)
    70-79126 (16.8)
    ≥8044 (5.9)
    PSA, mean±SD1.88±3.88
    HgA1c, mean±SD6.58±2.60
    FBG, mean±SD6.90±2.63
    BMI
    Underweight11 (1.5)
    Normal weight127 (17.6)
    Overweight300 (41.6)
    Obese283 (39.3)
    Smoking
    Yes111 (15.8)
    No584 (83.0)
    Prostate biopsy
    Yes15 (2.0)
    No734 (98.0)
    Diabetes
    Yes349 (46.7)
    No398 (53.3)
    Dyslipidemia
    Yes390 (52.6)
    No351 (47.4)
    Chronic kidney disease
    Yes40 (5.4)
    No701 (94.6)
    Hypertension
    Yes331 (44.5)
    No412 (55.5)
    • Values are presented as numbers and presentages (%). SD: standard deviation, PSA: prostate-specific antigen, HgA1c: hemoglobin A1c, FBG: fasting blood glucose, BMI: body mass index

    • View popup
    Table 2

    - Mean prostate-specific antigen levels among different subgroups.

    VariablesMean±SDP-values
    Age
    <401.03±0.600.001
    40-491.05±1.04
    50-591.31±1.27
    60-691.94±1.92
    70-792.99±8.29
    ≥803.41±4.67
    BMI
    Underweight9.74±27.230.001
    Normal weight2.07±2.47
    Overweight1.70±2.11
    Obese1.68±1.84
    Smoking
    Yes1.79±2.760.742
    No1.93±4.21
    Prostate biopsy
    Yes4.07±2.710.027
    No1.83±3.89
    Diabetes
    Yes1.73±1.940.327
    No2.01±5.01
    Dyslipidemia
    Yes1.77±2.010.739
    No2.01±5.26
    Chronic kidney disease
    Yes3.20±4.660.07
    No1.81±3.85
    Hypertension
    Yes1.99±2.420.49
    No1.79±4.77
    • Values are presented as mean ± standard deviation (SD).

    • BMI: body mass index

    • View popup
    Table 3

    - Correlation between prostate-specific antigen level, hemoglobin A1c, and fasting blood glucose.

    ProteinCorrelationHbA1cFBG
    PSAr0.040.04
    p0.300.34
    • PSA: prostate-specific antigen, HgA1c: hemoglobin A1c, FBG: fasting blood glucose

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Saudi Medical Journal: 44 (9)
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Association between body mass index and hemoglobin A1c with serum prostate-specific antigen level
Wejdan A. Alhamdan, Thamer A. Alsulaiman, Razan I. Alsabti, Ola M. Abdulmowla, Somayh E. Elnaggar, Yaser Alendijani
Saudi Medical Journal Sep 2023, 44 (9) 870-874; DOI: 10.15537/smj.2023.44.9.20230384

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Association between body mass index and hemoglobin A1c with serum prostate-specific antigen level
Wejdan A. Alhamdan, Thamer A. Alsulaiman, Razan I. Alsabti, Ola M. Abdulmowla, Somayh E. Elnaggar, Yaser Alendijani
Saudi Medical Journal Sep 2023, 44 (9) 870-874; DOI: 10.15537/smj.2023.44.9.20230384
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Keywords

  • prostate specific antigen
  • body mass index
  • diabetes
  • Saudi Arabia

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