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Research ArticleOriginal Article
Open Access

The immunologic abnormalities in patients with paroxysmal nocturnal hemoglobinuria are associated with disease progression

Guanrou Wang, Mengting Che, Lijie Zeng, Hui Liu, Liyan Li, Zhaoyun Liu and Rong Fu
Saudi Medical Journal April 2024, 45 (4) 424-432; DOI: https://doi.org/10.15537/smj.2024.45.4.20231010
Guanrou Wang
From the Department of Hematology, Tianjin Medical University General Hospital, Tianjin, People’s Republic of China.
MD
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Mengting Che
From the Department of Hematology, Tianjin Medical University General Hospital, Tianjin, People’s Republic of China.
MD
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Lijie Zeng
From the Department of Hematology, Tianjin Medical University General Hospital, Tianjin, People’s Republic of China.
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Hui Liu
From the Department of Hematology, Tianjin Medical University General Hospital, Tianjin, People’s Republic of China.
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Liyan Li
From the Department of Hematology, Tianjin Medical University General Hospital, Tianjin, People’s Republic of China.
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Zhaoyun Liu
From the Department of Hematology, Tianjin Medical University General Hospital, Tianjin, People’s Republic of China.
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Rong Fu
From the Department of Hematology, Tianjin Medical University General Hospital, Tianjin, People’s Republic of China.
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Article Information

vol. 45 no. 4 424-432
DOI 
https://doi.org/10.15537/smj.2024.45.4.20231010
PubMed 
38657993

Published By 
Saudi Medical Journal
Online ISSN 
1658-3175
History 
  • Received December 24, 2023
  • Accepted March 24, 2024
  • Published online April 23, 2024.

Copyright & Usage 
Copyright: © Saudi Medical Journal This is an Open Access journal and articles published are distributed under the terms of the Creative Commons Attribution-NonCommercial License (CC BY-NC). Readers may copy, distribute, and display the work for non-commercial purposes with the proper citation of the original work.

Author Information

  1. Guanrou Wang, MD,
  2. Mengting Che, MD,
  3. Lijie Zeng, MD,
  4. Hui Liu, MD,
  5. Liyan Li, MD,
  6. Zhaoyun Liu, MD and
  7. Rong Fu, MD
  1. From the Department of Hematology, Tianjin Medical University General Hospital, Tianjin, People’s Republic of China.
  1. Address correspondence and reprint request to: Dr. Rong Fu, Department of Hematology, Tianjin Medical University General Hospital, Tianjin, People’s Republic of China. E-mail: furong8369{at}tmu.edu.cn
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This article has been cited by the following articles in journals that are participating in Crossref Cited-by Linking.

  • Iptacopan Efficacy and Safety to Treat Paroxysmal Nocturnal Hemoglobinuria (PNH): A Systematic Review and Meta-Analysis
    Ibrahim M Dighriri, Reham M Al-Qahtani, Amal O Almutairi, Rahaf N Alhashbari, Hanin A Kanbeja, Salman A AlOjaimi, Mona A Aljuaid, Abdullah A Albaradi, Sahar T Almanjumi, Samah A Alqurashi, Maryam S Majrashi, Hatoon M Alansari, Ghayah A Jabbari, Abdulaziz S Alharbi, Amnah A Alnami
    Cureus 2024
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The immunologic abnormalities in patients with paroxysmal nocturnal hemoglobinuria are associated with disease progression
Guanrou Wang, Mengting Che, Lijie Zeng, Hui Liu, Liyan Li, Zhaoyun Liu, Rong Fu
Saudi Medical Journal Apr 2024, 45 (4) 424-432; DOI: 10.15537/smj.2024.45.4.20231010

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The immunologic abnormalities in patients with paroxysmal nocturnal hemoglobinuria are associated with disease progression
Guanrou Wang, Mengting Che, Lijie Zeng, Hui Liu, Liyan Li, Zhaoyun Liu, Rong Fu
Saudi Medical Journal Apr 2024, 45 (4) 424-432; DOI: 10.15537/smj.2024.45.4.20231010
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Keywords

  • paroxysmal nocturnal hemoglobinuria
  • T-cells
  • B-cells
  • dendritic cells
  • cytokines

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© 2025 Saudi Medical Journal Saudi Medical Journal is copyright under the Berne Convention and the International Copyright Convention.  Saudi Medical Journal is an Open Access journal and articles published are distributed under the terms of the Creative Commons Attribution-NonCommercial License (CC BY-NC). Readers may copy, distribute, and display the work for non-commercial purposes with the proper citation of the original work. Electronic ISSN 1658-3175. Print ISSN 0379-5284.

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