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Research ArticleOriginal Article
Open Access

Effect of cortisol and glycosylated-hemoglobin levels on mortality in intensive care unit

Oznur Sen, Ugur Uzun, Nurdan Aydin and Isil Guldogan
Saudi Medical Journal May 2024, 45 (5) 476-480; DOI: https://doi.org/10.15537/smj.2024.45.5.20240076
Oznur Sen
From the Department of Anesthesiology and Reanimation Unit (Sen, Aydin), SBU Haseki Training and Research Hospital, Istanbul; and From the Department of Anesthesiology and Reanimation Unit (Uzun, Guldogan), SBU Tepecik Training and Research Hospital, İzmir, Turkey.
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Ugur Uzun
From the Department of Anesthesiology and Reanimation Unit (Sen, Aydin), SBU Haseki Training and Research Hospital, Istanbul; and From the Department of Anesthesiology and Reanimation Unit (Uzun, Guldogan), SBU Tepecik Training and Research Hospital, İzmir, Turkey.
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Nurdan Aydin
From the Department of Anesthesiology and Reanimation Unit (Sen, Aydin), SBU Haseki Training and Research Hospital, Istanbul; and From the Department of Anesthesiology and Reanimation Unit (Uzun, Guldogan), SBU Tepecik Training and Research Hospital, İzmir, Turkey.
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Isil Guldogan
From the Department of Anesthesiology and Reanimation Unit (Sen, Aydin), SBU Haseki Training and Research Hospital, Istanbul; and From the Department of Anesthesiology and Reanimation Unit (Uzun, Guldogan), SBU Tepecik Training and Research Hospital, İzmir, Turkey.
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    Table 1

    - Demographic data of the patients included in the study

    CharacteristicValue
    Gender, n (%) 
    Female42 (53.2)
    Male37 (46.8)
    Age (years) *67 (19-96)
    Mortality, n (%) 
    Dead52 (65.8%)
    Discharged27 (34.2%)
    Day of stay in mechanical ventilator*7 (0-119)
    Day of stay in intensive care unit *16 (2-120)
    HBA1C (%)*5.7 (4.30-11.60)
    Cortisol (g/dl)*20.49 (0.88-62.20)
    Lactate (mmol/L)*1.5 (0.40-8.40)
    Blood Sugar (mg/dl)*143 (42-421)
    APACHE II*21 (7-46)
    • ↵* Median(min-max),

    • APACHE: Acute Physiology And Chronic Health Evaluation

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    Table 2

    - Laboratory data according to mortality status.

    GroupHBA1CCortisolLactateGlucose
    Mortality (n=52)    
    Median5.8026.691.65157.50
    Minimum4.807.980.7042.00
    Maximum11.5062.208.40421.00
    Discharged (n=27)    
    Median5.6017.141.40127.00
    Minimum4.300.880.4089.00
    Maximum11.6045.004.30309.00
    Total (n=79)    
    Median5.7020.491.50143.00
    Minimum4.300.880.4042.00
    Maximum11.6062.208.40421.00
    • HBA1C: hemoglobin A1C

    • View popup
    Table 3

    - Effect of variables on mortality.

    VariablesP-valueOdds ratio95% Confidence interval
    LowerUpper
    Cortisol0.0171.0781.0141.147
    HBA1C0.1660.5970.2881.239
    Age0.0821.0370.9951.081
    Lactate0.5011.2660.6372.516
    Glucose0.4391.0050.9931.017
    APACHE II Score0.0051.1711.0481.308
    • APACHE: Acute Physiology And Chronic Health Evaluation, HBA1C: hemoglobin A1c

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Saudi Medical Journal: 45 (5)
Saudi Medical Journal
Vol. 45, Issue 5
1 May 2024
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Effect of cortisol and glycosylated-hemoglobin levels on mortality in intensive care unit
Oznur Sen, Ugur Uzun, Nurdan Aydin, Isil Guldogan
Saudi Medical Journal May 2024, 45 (5) 476-480; DOI: 10.15537/smj.2024.45.5.20240076

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Effect of cortisol and glycosylated-hemoglobin levels on mortality in intensive care unit
Oznur Sen, Ugur Uzun, Nurdan Aydin, Isil Guldogan
Saudi Medical Journal May 2024, 45 (5) 476-480; DOI: 10.15537/smj.2024.45.5.20240076
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Keywords

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