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Research ArticleOriginal Article
Open Access

Magnetic resonance imaging of the breast

Could it be used as a screening test?

Deema A. Nagadi and Naglaa M. Elsayed
Saudi Medical Journal August 2024, 45 (8) 799-807; DOI: https://doi.org/10.15537/smj.2024.45.8.20230748
Deema A. Nagadi
From the Department of Diagnostic Radiology (Nagadi), King Abdulaziz University Hospital, from the Department of Radiologic Sciences (Nagadi, Elsayed), Faculty of Applied Medical Science, King Abdulaziz University, Jeddah, Kingdom of Saudi Arabia,and from the Department of Diagnostic Radiology (Elsayed), Faculty of Medicine, Cairo University, Cairo, Egypt.
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  • For correspondence: [email protected]
Naglaa M. Elsayed
From the Department of Diagnostic Radiology (Nagadi), King Abdulaziz University Hospital, from the Department of Radiologic Sciences (Nagadi, Elsayed), Faculty of Applied Medical Science, King Abdulaziz University, Jeddah, Kingdom of Saudi Arabia,and from the Department of Diagnostic Radiology (Elsayed), Faculty of Medicine, Cairo University, Cairo, Egypt.
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  • Figure 1
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    Figure 1

    - Algorithm showing the procedures carried out in all studied patients. MRI: magnetic resonance imaging, US: ultrasound

  • Figure 2
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    Figure 2

    - Comparisons of the tissue biopsy results. a) Diagnostic performance of mammogram vs tissue biopsy. b) Diagnostic performance of magnetic resonance imaging vs tissue biopsy. c) Diagnostic performance of ultrasound vs tissue biopsy. Mammo: mammogram, PPV: positive predictive value, NPV: negative predictive value, MRI: magnetic resonance imaging, US: ultrasound

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    Figure 3

    - Comparisons of ultrasound (US) and mammography results with magnetic resonance imaging (MRI). a) Diagnostic performance of US vs. MRI. b) Diagnostic performance of mammography vs. MRI. Mammo: mammogram, PPV: positive predictive value, NPV: negative predictive value, MRI: magnetic resonance imaging, US: ultrasound

Tables

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    Table 1

    - Mammogram, magnetic resonance imaging, and ultrasound results compared with tissue biopsy results.

    DiagnosisHistopathology final diagnosis
    Mammogram final diagnosisBenign (n=27)Malignant (n=56)Total (n=83)
    Benign11 (40.7)14 (25.0)25 (30.1)
    Malignant16 (59.3)42 (75.0)58 (69.9)
    MRI final diagnosisbenign (n=37)malignant (n=82)Total (n=119)
    Benign32 (86.5)25 (30.5)57 (47.9)
    Malignant5 (13.5)57 (69.5)62 (52.1)
    US final diagnosisbenign (n=34)malignant (n=65)Total (n=99)
    Benign24 (70.6)14 (21.5)38 (38.4)
    Malignant10 (29.4)51 (78.5)61 (61.6)

    Values are presented as numbers and percentages (%). MRI: magnetic resonance imaging, US: ultrasound

      • View popup
      Table 2

      - Comparison of ultrasound and mammography results with magnetic resonance imaging results.

      DiagnosisMRI final diagnosis
      US final diagnosisbenign (n=152)malignant (n=39)Total (n=191)
      Benign10216118
      86.4%13.6%100%
      67.1%41.0%61.8%
      Malignant502373
      68.5%31.5%100%
      32.9%59.0%38.2%
      Mammogram final diagnosisbenign (n=115)malignant (n=34)Total (n=149)
      Benign771693
      82.8%17.2%100%
      67.0%47.1%62.4%
      Malignant381856
      67.9%32.1%100%
      33.0%52.9%37.6%

      Values are presented as numbers and percentages (%). The first line of the percentage from 100% of the total benign rows and the second line of the percentage is 100% from the column. MRI: magnetic resonance imaging, US: ultrasound

        • View popup
        Table 3

        - Summary of performance for all procedures with or without tissue biopsy.

        ProceduresSensitivitySpecificityPPVNPVAccuracyKappa for agreement
        With tissue biopsy
        Mammogram75.0%41.0%72.0%44.0%64.0%Non-significant
        MRI70.0%87.0%92.0%56.0%75.0%Significant
        US79.0%71.0%84.0%63.0%76.0%Significant
        With MRI
        Mammogram53.0%67.0%32.0%83.0%64.0%Significant
        US59.0%67.0%32.0%86.0%65.0%Significant

        Values are presented as percentages (%). MRI: magnetic resonance imaging, US: ultrasound, PPV: positive predictive value, NPV: negative predictive value

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        Magnetic resonance imaging of the breast
        Deema A. Nagadi, Naglaa M. Elsayed
        Saudi Medical Journal Aug 2024, 45 (8) 799-807; DOI: 10.15537/smj.2024.45.8.20230748

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        Magnetic resonance imaging of the breast
        Deema A. Nagadi, Naglaa M. Elsayed
        Saudi Medical Journal Aug 2024, 45 (8) 799-807; DOI: 10.15537/smj.2024.45.8.20230748
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        Keywords

        • breast cancer
        • screening
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        • MRI
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