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Research ArticleOriginal Article
Open Access

Association between factor I fibrinogen (rs6050) and factor XI plasma thromboplastin (rs4253417) genetic polymorphisms and recurrent spontaneous miscarriage in Saudi women

Aaishah M. Kaabi, Afrah F. Alkhuriji, Zeneb A. Babay, Ibrahim A. Barakat, Abdullah M. Kaabi and Reem M. Kaabi
Saudi Medical Journal February 2025, 46 (2) 150-156; DOI: https://doi.org/10.15537/smj.2025.46.2.20240692
Aaishah M. Kaabi
From the Department of Zoology (Aaishah Kaabi, Al-Khuriji), College of Science; from the Department of Obstetrics and Gynecology (Babay)King Saud University; from the Central Military Laboratory & Blood Bank (Abdullah Kaabi), Prince Sultan Military Medical City, Riyadh; and from the Department of Laboratory and Blood Bank (Reem Kaabi), Al-Bukayriyah General Hospital, Qassim, Kingdom Saudi Arabia; and from the Cell Biology Department (Barakat), National Research Center, Giza, Egypt.
BSc, MSc
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  • For correspondence: [email protected]
Afrah F. Alkhuriji
From the Department of Zoology (Aaishah Kaabi, Al-Khuriji), College of Science; from the Department of Obstetrics and Gynecology (Babay)King Saud University; from the Central Military Laboratory & Blood Bank (Abdullah Kaabi), Prince Sultan Military Medical City, Riyadh; and from the Department of Laboratory and Blood Bank (Reem Kaabi), Al-Bukayriyah General Hospital, Qassim, Kingdom Saudi Arabia; and from the Cell Biology Department (Barakat), National Research Center, Giza, Egypt.
MD, PhD
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Zeneb A. Babay
From the Department of Zoology (Aaishah Kaabi, Al-Khuriji), College of Science; from the Department of Obstetrics and Gynecology (Babay)King Saud University; from the Central Military Laboratory & Blood Bank (Abdullah Kaabi), Prince Sultan Military Medical City, Riyadh; and from the Department of Laboratory and Blood Bank (Reem Kaabi), Al-Bukayriyah General Hospital, Qassim, Kingdom Saudi Arabia; and from the Cell Biology Department (Barakat), National Research Center, Giza, Egypt.
MD
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Ibrahim A. Barakat
From the Department of Zoology (Aaishah Kaabi, Al-Khuriji), College of Science; from the Department of Obstetrics and Gynecology (Babay)King Saud University; from the Central Military Laboratory & Blood Bank (Abdullah Kaabi), Prince Sultan Military Medical City, Riyadh; and from the Department of Laboratory and Blood Bank (Reem Kaabi), Al-Bukayriyah General Hospital, Qassim, Kingdom Saudi Arabia; and from the Cell Biology Department (Barakat), National Research Center, Giza, Egypt.
MSc, PhD
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Abdullah M. Kaabi
From the Department of Zoology (Aaishah Kaabi, Al-Khuriji), College of Science; from the Department of Obstetrics and Gynecology (Babay)King Saud University; from the Central Military Laboratory & Blood Bank (Abdullah Kaabi), Prince Sultan Military Medical City, Riyadh; and from the Department of Laboratory and Blood Bank (Reem Kaabi), Al-Bukayriyah General Hospital, Qassim, Kingdom Saudi Arabia; and from the Cell Biology Department (Barakat), National Research Center, Giza, Egypt.
BMLSc
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Reem M. Kaabi
From the Department of Zoology (Aaishah Kaabi, Al-Khuriji), College of Science; from the Department of Obstetrics and Gynecology (Babay)King Saud University; from the Central Military Laboratory & Blood Bank (Abdullah Kaabi), Prince Sultan Military Medical City, Riyadh; and from the Department of Laboratory and Blood Bank (Reem Kaabi), Al-Bukayriyah General Hospital, Qassim, Kingdom Saudi Arabia; and from the Cell Biology Department (Barakat), National Research Center, Giza, Egypt.
BMLSc
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Article Information

vol. 46 no. 2 150-156
DOI 
https://doi.org/10.15537/smj.2025.46.2.20240692
PubMed 
39933768

Published By 
Saudi Medical Journal
Online ISSN 
1658-3175
History 
  • Received November 19, 2024
  • Accepted January 24, 2025
  • Published online February 10, 2025.

Copyright & Usage 
Copyright: © Saudi Medical Journal This is an Open Access journal and articles published are distributed under the terms of the Creative Commons Attribution-NonCommercial License (CC BY-NC). Readers may copy, distribute, and display the work for non-commercial purposes with the proper citation of the original work.

Author Information

  1. Aaishah M. Kaabi, BSc, MSc⇑,
  2. Afrah F. Alkhuriji, MD, PhD,
  3. Zeneb A. Babay, MD,
  4. Ibrahim A. Barakat, MSc, PhD,
  5. Abdullah M. Kaabi, BMLSc and
  6. Reem M. Kaabi, BMLSc
  1. From the Department of Zoology (Aaishah Kaabi, Al-Khuriji), College of Science; from the Department of Obstetrics and Gynecology (Babay)King Saud University; from the Central Military Laboratory & Blood Bank (Abdullah Kaabi), Prince Sultan Military Medical City, Riyadh; and from the Department of Laboratory and Blood Bank (Reem Kaabi), Al-Bukayriyah General Hospital, Qassim, Kingdom Saudi Arabia; and from the Cell Biology Department (Barakat), National Research Center, Giza, Egypt.
  1. Address correspondence and reprint request to: Dr. Aaishah M. Kaabi, Department of Zoology, College of Science, King Saud University, Riyadh, Kingdom of Saudi Arabia. E-mail: kaby{at}qu.edu.sa
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Association between factor I fibrinogen (rs6050) and factor XI plasma thromboplastin (rs4253417) genetic polymorphisms and recurrent spontaneous miscarriage in Saudi women
Aaishah M. Kaabi, Afrah F. Alkhuriji, Zeneb A. Babay, Ibrahim A. Barakat, Abdullah M. Kaabi, Reem M. Kaabi
Saudi Medical Journal Feb 2025, 46 (2) 150-156; DOI: 10.15537/smj.2025.46.2.20240692

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Association between factor I fibrinogen (rs6050) and factor XI plasma thromboplastin (rs4253417) genetic polymorphisms and recurrent spontaneous miscarriage in Saudi women
Aaishah M. Kaabi, Afrah F. Alkhuriji, Zeneb A. Babay, Ibrahim A. Barakat, Abdullah M. Kaabi, Reem M. Kaabi
Saudi Medical Journal Feb 2025, 46 (2) 150-156; DOI: 10.15537/smj.2025.46.2.20240692
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Keywords

  • Single-nucleotide polymorphisms (SNPs)
  • TaqMan assay
  • clotting factors
  • genomic DNA
  • factor I fibrinogen
  • factor XI plasma thromboplastin
  • Recurrent spontaneous miscarriage

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© 2025 Saudi Medical Journal Saudi Medical Journal is copyright under the Berne Convention and the International Copyright Convention.  Saudi Medical Journal is an Open Access journal and articles published are distributed under the terms of the Creative Commons Attribution-NonCommercial License (CC BY-NC). Readers may copy, distribute, and display the work for non-commercial purposes with the proper citation of the original work. Electronic ISSN 1658-3175. Print ISSN 0379-5284.

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