Management of treatment-naïve limited-stage small cell esophagus carcinoma

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Figure 1
Histological and immunohistochemical assessment of small cell carcinoma A) Hematoxylin and Eosin (H&E) staining demonstrated small cells with hyperchromatic nuclei and scant cytoplasm (original magnification × 200); B) & C) the tumor cells showed positive immuno-staining intensity for neuron specific enolase and synaptophysin (original magnification × 200).
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Figure 2
Survival according to the different biopsy pathology and treatment. Group A - patients were diagnosed with small cell esophagus carcinoma (SCEC) by the biopsy, and received chemoradiotherapy without surgery as initial treatment; Group B - patients were diagnosed with SCEC by the biopsy, and received surgery as initial treatment; Group C - patients with poorly differentiated carcinoma-not otherwise specific or negative pathological findings of the biopsy and received surgery as initial treatment. The media overall survival of Group A was unreached, and was 16.2 months for Group B and 21.1 for Group C. Among the 3 groups, p=0.037; Group B versus Group A, p=0.019; Group B versus Group C, p=0.119; Group C versus Group A, p=0.089.