Skip to main content

Main menu

  • Home
  • Content
    • Latest
    • Archive
    • home
  • Info for
    • Authors
    • Reviewers
    • Subscribers
    • Institutions
    • Advertisers
    • Join SMJ
  • About Us
    • About Us
    • Editorial Office
    • Editorial Board
  • More
    • Advertising
    • Alerts
    • Feedback
    • Folders
    • Help
  • Other Publications
    • NeuroSciences Journal

User menu

  • My alerts
  • Log in

Search

  • Advanced search
Saudi Medical Journal
  • Other Publications
    • NeuroSciences Journal
  • My alerts
  • Log in
Saudi Medical Journal

Advanced Search

  • Home
  • Content
    • Latest
    • Archive
    • home
  • Info for
    • Authors
    • Reviewers
    • Subscribers
    • Institutions
    • Advertisers
    • Join SMJ
  • About Us
    • About Us
    • Editorial Office
    • Editorial Board
  • More
    • Advertising
    • Alerts
    • Feedback
    • Folders
    • Help
  • Follow psmmc on Twitter
  • Visit psmmc on Facebook
  • RSS
Review ArticleReview Article
Open Access

Nigella sativa and its active constituent thymoquinone in oral health

Safia A. AlAttas, Fat’heya M. Zahran and Shereen A. Turkistany
Saudi Medical Journal March 2016, 37 (3) 235-244; DOI: https://doi.org/10.15537/smj.2016.3.13006
Safia A. AlAttas
From the Department of Oral Diagnostic Sciences (Al-Attas, Zahran), Faculty of Dentistry, the Centre of Innovation in Personalized Medicine (Turkistany), King Abdulaziz University, Jeddah, Kingdom of Saudi Arabia
MS, FAAOM
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • For correspondence: [email protected]
Fat’heya M. Zahran
From the Department of Oral Diagnostic Sciences (Al-Attas, Zahran), Faculty of Dentistry, the Centre of Innovation in Personalized Medicine (Turkistany), King Abdulaziz University, Jeddah, Kingdom of Saudi Arabia
MS, PhD
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Shereen A. Turkistany
From the Department of Oral Diagnostic Sciences (Al-Attas, Zahran), Faculty of Dentistry, the Centre of Innovation in Personalized Medicine (Turkistany), King Abdulaziz University, Jeddah, Kingdom of Saudi Arabia
BD, MS
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • Article
  • Figures & Data
  • eLetters
  • Info & Metrics
  • References
  • PDF
Loading

Article Information

vol. 37 no. 3 235-244
DOI 
https://doi.org/10.15537/smj.2016.3.13006
PubMed 
26905343

Published By 
Saudi Medical Journal
Online ISSN 
1658-3175
History 
  • Published online March 1, 2016.

Copyright & Usage 
Copyright: © Saudi Medical Journal This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Author Information

  1. Safia A. AlAttas, MS, FAAOM⇑,
  2. Fat’heya M. Zahran, MS, PhD and
  3. Shereen A. Turkistany, BD, MS
  1. From the Department of Oral Diagnostic Sciences (Al-Attas, Zahran), Faculty of Dentistry, the Centre of Innovation in Personalized Medicine (Turkistany), King Abdulaziz University, Jeddah, Kingdom of Saudi Arabia
  1. Address correspondence and reprint request to: Professor Safia A. AlAttas, Department of Oral Diagnostic Sciences, Faculty of Dentistry, King Abdulaziz University, Jeddah, Kingdom of Saudi Arabia. E-mail: salattass{at}kau.edu.sa
View Full Text

Cited By...

  • 42 Citations
  • 52 Citations
  • Google Scholar

This article has been cited by the following articles in journals that are participating in Crossref Cited-by Linking.

  • An updated knowledge of Black seed (Nigella sativa Linn.): Review of phytochemical constituents and pharmacological properties
    Md Faruque Ahmad, Fakhruddin Ali Ahmad, Syed Amir Ashraf, Hisham H. Saad, Shadma Wahab, Mohammed Idreesh Khan, M. Ali, Syam Mohan, Khalid Rehman Hakeem, Md Tanwir Athar
    Journal of Herbal Medicine 2021 25
  • Cytotoxicity of thymoquinone alone or in combination with cisplatin (CDDP) against oral squamous cell carcinoma in vitro
    Omar M. Alaufi, Abdulwahab Noorwali, Fatheya Zahran, Ahmed M. Al-Abd, Safia Al-Attas
    Scientific Reports 2017 7 1
  • Prophetic Medicine-Nigella Sativa (Black cumin seeds) – Potential herb for COVID-19?
    Naina Mohamed Pakkir Maideen
    Journal of Pharmacopuncture 2020 23 2
  • Extraction, characterization and bioactive properties of Nigella sativa seedcake
    Deepak Kadam, S. S. Lele
    Journal of Food Science and Technology 2017 54 12
  • Nigella sativa and Thymoquinone: A Natural Blessing for Periodontal Therapy
    Mohamed Mekhemar, Yasmine Hassan, Christof Dörfer
    Antioxidants 2020 9 12
  • Senescent Colon and Breast Cancer Cells Induced by Doxorubicin Exhibit Enhanced Sensitivity to Curcumin, Caffeine, and Thymoquinone
    Ali H. El-Far, Noureldien H. E. Darwish, Shaker A. Mousa
    Integrative Cancer Therapies 2020 19
  • Natural therapeutic approach of Nigella sativa (Black seed) fixed oil in management of Sinusitis
    Mohaddese Mahboubi
    Integrative Medicine Research 2018 7 1
  • An updated literature-based review: phytochemistry, pharmacology and therapeutic promises of Nigella sativa L.
    Muhammad Torequl Islam, Md. Roich Khan, Siddhartha Kumar Mishra
    Oriental Pharmacy and Experimental Medicine 2019 19 2
  • A Review on Extraction, Characterization, and Applications of Bioactive Peptides From Pressed Black Cumin Seed Cake
    Ahmed A. Zaky, Jae-Han Shim, A. M. Abd El-Aty
    Frontiers in Nutrition 2021 8
  • Salvadora persica: Nature’s Gift for Periodontal Health
    Mohamed Mekhemar, Mathias Geib, Manoj Kumar, Radha, Yasmine Hassan, Christof Dörfer
    Antioxidants 2021 10 5
  • Thymoquinone binds and activates human salivary aldehyde dehydrogenase: Potential therapy for the mitigation of aldehyde toxicity and maintenance of oral health
    Amaj Ahmed Laskar, Masood Alam Khan, Fizza Askari, Hina Younus
    International Journal of Biological Macromolecules 2017 103
  • Fabrication of a Polycaprolactone/Chitosan Nanofibrous Scaffold Loaded with Nigella sativa Extract for Biomedical Applications
    Qasim Shakir Kahdim, Najmeddine Abdelmoula, Hassan Al-Karagoly, Salim Albukhaty, Jabbar Al-Saaidi
    BioTech 2023 12 1
  • Metabolomics driven analysis of Nigella sativa seeds identifies the impact of roasting on the chemical composition and immunomodulatory activity
    Mohamed A. Salem, Riham A. El-Shiekh, Nora M. Aborehab, Ahmed A. Al‐Karmalawy, Shahira M. Ezzat, Saleh Alseekh, Alisdair R. Fernie
    Food Chemistry 2023 398
  • Development and Optimization of Methylcellulose-Based Nanoemulgel Loaded with Nigella sativa Oil for Oral Health Management: Quadratic Model Approach
    Muhammad H. Sultan, Shamama Javed, Osama Ali Madkhali, Mohammad Intakhab Alam, Yosif Almoshari, Mohammad Ali Bakkari, Durgaramani Sivadasan, Ahmad Salawi, Ameena Jabeen, Waquar Ahsan
    Molecules 2022 27 6
  • Nigellalogy: A Review on Nigella Sativa
    Torequl Islam
    MOJ Bioequivalence & Bioavailability 2017 3 6
  • Deodorizing Substance in Black Cumin (<i>Nigella sativa</i> L.) Seed Oil
    Toru Nakasugi, Takushi Murakawa, Koji Shibuya, Masanori Morimoto
    Journal of Oleo Science 2017 66 8
  • Removal of microbial pathogens and anticancer activity of synthesized nano-thymoquinone from Nigella sativa seeds
    Prathiba Gnanasekaran, Anitha Roy, Nagabhishek Sirpu Natesh, Varshini Raman, Priyanka Ganapathy, Madan Kumar Arumugam
    Environmental Technology & Innovation 2021 24
  • Isolates fromMonechma ciliatumseeds' extract hamperedPorphyromonas gingivalishemagglutinins
    Sara A. Eltigani, Mohamed M. Eltayeb, Atsushi Ishihara, Jiro Arima
    Journal of Food Biochemistry 2019 43 11
  • Awareness and Current Therapeutics of Asthma
    Rida Zainab, Muhammad Akram, Muhammad Daniyal, Muhammad Riaz
    Dose-Response 2019 17 3
  • Evaluation of the Antimicrobial Effect of Thymoquinone against Different Dental Pathogens: An In Vitro Study
    Khalifa S. Al-Khalifa, Rasha AlSheikh, Moahmmed T. Al-Hariri, Hosam El-Sayyad, Maher S. Alqurashi, Saqib Ali, Amr S. Bugshan
    Molecules 2021 26 21
  • Nigella sativa toothpaste promotes anti-inflammatory and anti-destructive effects in a rat model of periodontitis
    Ernie Maduratna Setiawatie, Maria Apriliani Gani, Retno Puji Rahayu, Noer Ulfah, Shafira Kurnia, Eka Fitria Augustina, Desi Sandra Sari
    Archives of Oral Biology 2022 137
  • A comprehensive perspective of traditional Arabic or Islamic medicinal plants as an adjuvant therapy against COVID-19
    Shabina Ishtiaq Ahmed, Sehrish Jamil, Humaira Ismatullah, Rashid Hussain, Shabana Bibi, Mayeen Uddin Khandaker, Aisha Naveed, Abubakr M. Idris, Talha Bin Emran
    Saudi Journal of Biological Sciences 2023 30 3
  • A Comparative Study on Alvogyl and a Mixture of Black Seed Oil and Powder for Alveolar Osteitis: A Randomized Double-Blind Controlled Clinical Trial
    Zafar Ali Khan, Namdeo Prabhu, Naseer Ahmed, Abhishek Lal, Rakhi Issrani, Afsheen Maqsood, Fahim Vohra, Mohammad Khursheed Alam, Andrea Scribante
    International Journal of Clinical Practice 2022 2022
  • Evaluation of antibacterial activity of Nigella sativa seed extract against Porphyromonas gingivalis and Prevotella intermedia
    Kowsalya Senthilnathan, Paavai Ilango, T Abirami, VasanthAyswarya Vummidi, ArulPari Mahalingam, VineelaKatam Reddy
    Journal of Interdisciplinary Dentistry 2020 10 2
  • Evaluation of the remineralizing potential of Nigella sativa, sodium fluoride and caesin phosphopeptide-amorphous calcium phosphate on enamel: An In vitro study
    NKiran Kumar, SavithaB Naik, CH Laxmi Priya, Seema Merwade, Biji Brigit, CN Guruprasad, Pavithra Prabakaran
    Journal of Indian Association of Public Health Dentistry 2020 18 4
  • Insights into the antioxidant, anti-inflammatory and anti-microbial potential of Nigella sativa essential oil against oral pathogens
    Shaeesta Khaleelahmed Bhavikatti, Siti Lailatul Akmar Zainuddin, Rosmaliza Binti Ramli, Sameer J. Nadaf, Padma B. Dandge, Masidd Khalate, Mohmed Isaqali Karobari
    Scientific Reports 2024 14 1
  • Oilseeds: Health Attributes and Food Applications
    Paras Sharma, T. Longvah
    2021
  • Alteration of Multi-drug Resistance Activities by Ethanolic Extracts of Nigella sativa Against Urinary Pathogens
    Sugapriya Dhanasekar
    International Journal of Pharmacology 2019 15 8
  • Comparative evaluation of the efficacy of Nigella sativa (75% v/v) cream and clobetasol propionate (0.05% w/w) gel in oral lichen planus—a double-blinded randomized control trial
    Lokesh Kumar S, Zameera Naik, Arun Panwar, Sridhar M, Vaishali Keluskar, Ram Surath Kumar
    Oral and Maxillofacial Surgery 2022 28 1
  • Impact of the Current Scenario and Future Perspectives for the Management of Oral Diseases: Remarkable Contribution of Herbs in Dentistry
    Ashima Ahuja, Sonia Singh
    Anti-Infective Agents 2022 20 5
  • A Comprehensive Review of the Antioxidant, Antimicrobial, and Therapeutic Efficacies of Black Cumin (Nigella sativa L.) Seed Oil and Its Thymoquinone
    Gourab Chatterjee, Asit Kumar Saha, Shamama Khurshid, Achintya Saha
    Journal of Medicinal Food 2025 28 4
  • Black Seeds
    Keith W. Singletary
    Nutrition Today 2022 57 6
  • Comparative Clinical Study of the Effect of Nigella Sativa Oil on Soft Tissue Healing and Inflammation Reduction Compared to Eugenol in the Context of Dry Socket
    Mohamad Alabdullah, Zafin Z Kara Beit, Asaad Shehada
    Cureus 2023
  • Nigella sativa oil as a treatment for gingivitis
    Ishrat Rahman, Afrah Mohammed, Manal A. AlSheddi, Alanoud Algazlan, Alanoud Alwably, Mamata Hebbal, Maha Galal Omar
    Asian Pacific Journal of Tropical Medicine 2023 16 3
  • Antibacterial Effects of Black Cumin Seed Oil on Oral Microcosm Biofilms
    Ahyun Jo, Hee-Eun Kim
    Microorganisms 2024 12 10
  • Different dressing materials for pulpotomy: A review
    Rakhshuda Manzoor, Manohar Bhatt, Abhishek Kherwa, Bibin Jacob Emmanuel, Marikinda Manzoor
    IP Indian Journal of Conservative and Endodontics 2021 6 2
  • Effects of Nigella sativa Oil Fractions on Reactive Oxygen Species and Chemokine Expression in Airway Smooth Muscle Cells
    Asma Mosbah, Hanane Khither, Camélia Mosbah, Abdelkader Slimani, Abdelkader Mahrouk, Salah Akkal, Gema Nieto
    Plants 2023 12 11
  • Molecular and Therapeutic actions of Thymoquinone
    Hina Younus
    2018
  • Nigella sativa 3% Inhibition Test of Nаturаl Toothpаste Compаred Cetylpyridinum chloride (CPC) Toothpаste 0.01-0.1% on Аggregаtibаcter actinomycetemcomitаns
    Ernie Maduratna Setiawatie, Prihartini Widiyanti, Retno Puji Rahayu, Alifiani Eprilina, Desi Sandrasari, Irma Yosephina Savitri, Lambang Bargowo, Rihandhita Shinta Meiliana
    Indonesian Journal of Tropical and Infectious Disease 2023 11 3
  • Plant polyphenols, terpenes, and terpenoids in oral health
    Vida Arzani, Mohsen Soleimani, Tilman Fritsch, Ursula M. Jacob, Vittorio Calabrese, Ahmad Arzani
    Open Medicine 2025 20 1
  • Allium sativum
    Nidhi Chugh, Vela Desai, Rajeev Sharma, Paresh Chandwani
    Saudi Journal of Oral Sciences 2023 10 1
  • An Assessment of the Clinical Efficacy of a Topical Application of 5% Thymoquinone Gel for Plaque-Induced Gingivitis Patients: A Randomized Controlled Clinical Trial
    Ahmad H. Almehmadi, Khalid Aljohani
    Healthcare 2024 12 18
  • Biochemistry, Nutrition, and Therapeutics of Black Cumin Seed
    Abdalbasit Adam Mariod, Haroon Elrasheid Tahir
    2023
  • Clinical Efficacy of a Novel Lipid-based Thymoquinone Gel
    Saima Y Khan, Imran Ahmad
    Journal of International Society of Preventive and Community Dentistry 2021 11 4
  • Comparing the efficacy of a novel mucoadhesive patch containing Nigella sativa 10% with triamcinolone 0.1% in patients with erosive‐atrophic oral lichen planus: A pilot study
    Atessa Pakfetrat, Zahra Delavarian, Mahshid Malakooti, Hossein Bagheri, Habibollah Esmaily, Mahsa Ghorbani, Pooya Saeedi
    Clinical and Experimental Dental Research 2024 10 3
  • Ellagic acid protected the gingival tissue via fibroblast and epidermal growth factors in rats
    Gülüçağ Giray Tekin, Buşra Deveci, Engin Deveci
    Acta Cirúrgica Brasileira 2024 39
  • Evaluating the protective effect of a nanoemulsion containing propolis and Nigella sativa nanoparticles on enamel surface
    Hedieh Khanabadi, Faeze Hamze, Mahnaz Amiri, Sepideh Behzadi, Hanieh Sadat Emami Razavi, Mehrdad Karimi
    Journal of Oral Health and Oral Epidemiology 2024 13 3
  • Evaluation of thymoquinone cancer chemo-preventive effect on oral leukoplakia: a randomized clinical trial
    Ghada Nabil, Fat’heya M. Zahran, Aliaa ElMeshad, Ahmed Fawzy, Dalia Ghalwash, Basma Elsaadany
    Exploration of Medicine 2025
  • Medicinal Plants
    Sally Elnawasany
    2022
  • Natural Products and Their Promise Against COVID 19: Review
    Fatma Abo-Elghiet, Hanan M. Alharbi, Abeer Temraz
    Current Nutrition & Food Science 2022 18 2
  • Recent Developments in Antioxidants from Natural Sources
    Kehinde Sowunmi, Zeenat Kaka
    2023 41
  • Synergistic antimicrobial action of chitosan-neem extracts nanoformulation as a promising strategy for overcoming multi-drug resistant bacteria
    Sanaa J. Almowallad, Leena S. Alqahtani
    International Journal of Biological Macromolecules 2024 272
PreviousNext
Back to top

In this issue

Saudi Medical Journal: 37 (3)
Saudi Medical Journal
Vol. 37, Issue 3
1 Mar 2016
  • Table of Contents
  • Cover (PDF)
  • Index by author
Print
Download PDF
Email Article

Thank you for your interest in spreading the word on Saudi Medical Journal.

NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.

Enter multiple addresses on separate lines or separate them with commas.
Nigella sativa and its active constituent thymoquinone in oral health
(Your Name) has sent you a message from Saudi Medical Journal
(Your Name) thought you would like to see the Saudi Medical Journal web site.
Citation Tools
Nigella sativa and its active constituent thymoquinone in oral health
Safia A. AlAttas, Fat’heya M. Zahran, Shereen A. Turkistany
Saudi Medical Journal Mar 2016, 37 (3) 235-244; DOI: 10.15537/smj.2016.3.13006

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
Share
Nigella sativa and its active constituent thymoquinone in oral health
Safia A. AlAttas, Fat’heya M. Zahran, Shereen A. Turkistany
Saudi Medical Journal Mar 2016, 37 (3) 235-244; DOI: 10.15537/smj.2016.3.13006
Twitter logo Facebook logo Mendeley logo
  • Tweet Widget
  • Facebook Like
  • Google Plus One
Bookmark this article

Jump to section

  • Article
    • Abstract
    • Footnotes
    • References
  • Figures & Data
  • eLetters
  • References
  • Info & Metrics
  • PDF

Related Articles

  • No related articles found.
  • PubMed
  • Google Scholar

Cited By...

  • No citing articles found.
  • Google Scholar

More in this TOC Section

  • Harnessing artificial intelligence for infection control and prevention in hospitals
  • Effects of antidiabetic drugs on the level of serum uric acid in patients who have type 2 diabetes
  • The future of personalized medicine in Saudi Arabia
Show more Review Article

Similar Articles

CONTENT

  • home

JOURNAL

  • home

AUTHORS

  • home
Saudi Medical Journal

© 2025 Saudi Medical Journal Saudi Medical Journal is copyright under the Berne Convention and the International Copyright Convention.  Saudi Medical Journal is an Open Access journal and articles published are distributed under the terms of the Creative Commons Attribution-NonCommercial License (CC BY-NC). Readers may copy, distribute, and display the work for non-commercial purposes with the proper citation of the original work. Electronic ISSN 1658-3175. Print ISSN 0379-5284.

Powered by HighWire