Sonic hedgehog, TBX18, and TSHZ3 proteins involved in pyeloureteral motility development are overexpressed in ureteropelvic junction obstruction

References

1. ↵
   1. Coran AG

   1. Groth TW,
   2. Mitchell ME

   (2012) in Pediatric Surgery, Ureteropelvic Junction Obstruction, ed Coran AG (Elsevier Saunders, Philadelphia (US)), 7th ed, pp 1411–1425.
2. ↵
   1. Coran AG,
   2. Adzick NS,
   3. Krummel TM,
   4. Laberge JM,
   5. Shamberger RC,
   6. Caldamone AA

   (2012) Pediatric Surgery (Elsevier Saunders, Philadelphia (US)), 7th ed.
3. ↵
   1. Zhang PL,
   2. Peters CA,
   3. Rosen S

   (2000) Ureteropelvic junction obstruction: morphological and clinical studies. Pediatr Nephrol 14:820–826.

   OpenUrlCrossRefPubMedWeb of Science
4. 1. Kim WJ,
   2. Yun SJ,
   3. Lee TS,
   4. Kim CW,
   5. Lee HM,
   6. Choi H

   (2000) Collagen-to-smooth muscle ratio helps prediction of prognosis after pyeloplasty. J Urol 163:1271–1275.

   OpenUrlPubMed
5. ↵
   1. Murakumo M,
   2. Nonomura K,
   3. Yamashita T,
   4. Ushiki T,
   5. Abe K,
   6. Koyanagi T

   (1997) Structural changes of collagen components and diminution of nerves in congenital ureteropelvic junction obstruction. J Urol 157:1963–1968.

   OpenUrlCrossRefPubMedWeb of Science
6. ↵
   1. Wang GJ,
   2. Brenner-Anantharam A,
   3. Vaughan ED,
   4. Herzlinger D

   (2009) Antagonism of BMP4 signaling disrupts smooth muscle investment of the ureter and ureteropelvic junction. J Urol 181:401–407.

   OpenUrlPubMedWeb of Science
7. ↵
   1. Yu J,
   2. Carroll TJ,
   3. McMahon AP

   (2002) Sonic hedgehog regulates proliferation and differentiation of mesenchymal cells in the mouse metanephric kidney. Development 129:5301–5312.

   OpenUrlPubMedWeb of Science
8. ↵
   1. Airik R,
   2. Bussen M,
   3. Singh MK,
   4. Petry M,
   5. Kispert A

   (2006) Tbx18 regulates the development of the ureteral mesenchyme. J Clin Invest 116:663–674.

   OpenUrlCrossRefPubMedWeb of Science
9. ↵
   1. Jenkins D,
   2. Caubit X,
   3. Dimovski A,
   4. Matevska N,
   5. Lye CM,
   6. Cabuk F,
   7. et al.

   (2010) Analysis of TSHZ2 and TSHZ3 genes in congenital pelvi-ureteral junction obstruction. Nephrol Dial Transplant 25:54–60.

   OpenUrlCrossRefPubMed
10. ↵
    1. Zhou D,
    2. Li Y,
    3. Zhou L,
    4. Tan RJ,
    5. Xiao L,
    6. Liang M,
    7. et al.

    (2014) Sonic hedgehog is a novel tubule-derived growth factor for interstitial fibroblasts after kidney injury. J Am Soc Nephrol 25:2187–2200.

    OpenUrlAbstract/FREE Full Text
11. ↵
    1. Xu J,
    2. Nie X,
    3. Cai X,
    4. Cai CL,
    5. Xu PX

    (2014) Tbx18 is essential for normal development of vasculature network and glomerular mesangium in the mammalian kidney. Dev Biol 391:17–31.

    OpenUrlCrossRefPubMed
12. ↵
    1. Caubit X,
    2. Lye CM,
    3. Martin E,
    4. Coré N,
    5. Long DA,
    6. Vola C,
    7. et al.

    (2008) Teashirt 3 is necessary for ureteral smooth muscle differentiation downstream of SHH and BMP4. Development 135:3301–3310.

    OpenUrlAbstract/FREE Full Text
13. ↵
    1. Ellerkamp V,
    2. Kurth RR,
    3. Schmid E,
    4. Zundel S,
    5. Warmann SW,
    6. Fuchs J

    (2016) Differences between intrinsic and extrinsic ureteropelvic junction obstruction related to crossing vessels: histology and functional analyses. World J Urol 34:577–583.

    OpenUrl
14. ↵
    1. Richstone L,
    2. Seideman CA,
    3. Reggio E,
    4. Bluebond-Langner R,
    5. Pinto PA,
    6. Trock B,
    7. Kavoussi LR

    (2009) Pathologic findings in patients with ureteropelvic junction obstruction and crossing vessels. Urology 73:716–719.

    OpenUrlPubMed