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Research ArticleOriginal Article
Open Access

Effects of different dosages of oxycodone and fentanyl on the hemodynamic changes during intubation

Ki-Bum Park, Junggun Ann and Haemi Lee
Saudi Medical Journal August 2016, 37 (8) 847-852; DOI: https://doi.org/10.15537/smj.2016.8.14822
Ki-Bum Park
From the Department of Anesthesiology and Pain Medicine (Park), School of Medicine, Keimyung University Dongsan Hospital, and the Department of Anesthesiology and Pain Medicine (Ann & Lee), College of Medicine, Yeungnam University, Daegu, Korea
MD
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Junggun Ann
From the Department of Anesthesiology and Pain Medicine (Park), School of Medicine, Keimyung University Dongsan Hospital, and the Department of Anesthesiology and Pain Medicine (Ann & Lee), College of Medicine, Yeungnam University, Daegu, Korea
MD
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Haemi Lee
From the Department of Anesthesiology and Pain Medicine (Park), School of Medicine, Keimyung University Dongsan Hospital, and the Department of Anesthesiology and Pain Medicine (Ann & Lee), College of Medicine, Yeungnam University, Daegu, Korea
MD, PhD
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    Figure 1

    Changes in mean blood pressure (MBP) in each group during study period (mean ± standard deviation [SD]). Group F: fentanyl (2 µg/kg), Group O/70: oxycodone 140 µg/kg, Group O/100: oxycodone 200 µg/kg. T1 = baseline, T2 = just before intubation, T3 = one minute after intubation, T4 = 7.5 minutes after intubation. MBP showed no significant difference among the 3 groups at all periods of induction.

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    Figure 2

    Changes in heart rate (HR) in each group during study period. Group F: fentanyl (2 µg/kg), Group O/70: oxycodone 140 µg/kg, Group O/100: oxycodone 200 µg/kg. T1 = baseline, T2 = just before intubation, T3 = one minute after intubation, T4 = 7.5 minutes after intubation. A significant difference was noted between Group O/70 and Group O/100 at T3 (p=0.04).

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    Figure 3

    Changes in peripheral oxygen saturation (SpO2) in each group during study period. Group F: fentanyl (2 µg/kg), Group O/70: oxycodone 140 µg/kg, Group O/100: oxycodone 200 µg/kg. T1 = baseline, T2 = just before intubation, T3 = one minute after intubation, T4 = 7.5 minutes after intubation. SpO2 showed no significant difference among the groups.

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    Figure 4

    Changes in bispectral index (BIS) in each group during study period. Group F: fentanyl (2 µg/kg), Group O/70: oxycodone 140 µg/kg, Group O/100: oxycodone 200 µg/kg. T1 = baseline, T2 = just before intubation, T3 = one minute after intubation, T4 = 7.5 minutes after intubation. BIS was comparable in all groups.

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Saudi Medical Journal: 37 (8)
Saudi Medical Journal
Vol. 37, Issue 8
1 Aug 2016
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Effects of different dosages of oxycodone and fentanyl on the hemodynamic changes during intubation
Ki-Bum Park, Junggun Ann, Haemi Lee
Saudi Medical Journal Aug 2016, 37 (8) 847-852; DOI: 10.15537/smj.2016.8.14822

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Effects of different dosages of oxycodone and fentanyl on the hemodynamic changes during intubation
Ki-Bum Park, Junggun Ann, Haemi Lee
Saudi Medical Journal Aug 2016, 37 (8) 847-852; DOI: 10.15537/smj.2016.8.14822
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