Skip to main content

Main menu

  • Home
  • Content
    • Latest
    • Archive
    • home
  • Info for
    • Authors
    • Reviewers
    • Subscribers
    • Institutions
    • Advertisers
    • Join SMJ
  • About Us
    • About Us
    • Editorial Office
    • Editorial Board
  • More
    • Advertising
    • Alerts
    • Feedback
    • Folders
    • Help
  • Other Publications
    • NeuroSciences Journal

User menu

  • My alerts
  • Log in
  • Log out

Search

  • Advanced search
Saudi Medical Journal
  • Other Publications
    • NeuroSciences Journal
  • My alerts
  • Log in
  • Log out
Saudi Medical Journal

Advanced Search

  • Home
  • Content
    • Latest
    • Archive
    • home
  • Info for
    • Authors
    • Reviewers
    • Subscribers
    • Institutions
    • Advertisers
    • Join SMJ
  • About Us
    • About Us
    • Editorial Office
    • Editorial Board
  • More
    • Advertising
    • Alerts
    • Feedback
    • Folders
    • Help
  • Follow psmmc on Twitter
  • Visit psmmc on Facebook
  • RSS
Research ArticleOriginal Article
Open Access

Long-term use of bisphosphonates in osteoporosis

Basmah K. Alwahhabi and Basil A. Alsuwaine
Saudi Medical Journal June 2017, 38 (6) 604-608; DOI: https://doi.org/10.15537/smj.2017.6.19793
Basmah K. Alwahhabi
From the Department of Endocrinology and Diabetes (Alwahhabi), Prince Sultan Military Medical City and the College of Medicine (Alsuwaine), King Saud University, Riyadh, Kingdom of Saudi Arabia
MD
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • For correspondence: [email protected]
Basil A. Alsuwaine
From the Department of Endocrinology and Diabetes (Alwahhabi), Prince Sultan Military Medical City and the College of Medicine (Alsuwaine), King Saud University, Riyadh, Kingdom of Saudi Arabia
MD
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • Article
  • Figures & Data
  • eLetters
  • Info & Metrics
  • References
  • PDF
Loading

References

  1. ↵
    1. Black DM,
    2. Cummings SR,
    3. Karpf DB,
    4. Cauley JA,
    5. Thompson DE
    (1996) Randomized trial of effect of alendronate on risk of fracture in women with existing vertebral fractures. Fracture Intervention Trial Research. Lancet 348:1535–1541.
    OpenUrlCrossRefPubMedWeb of Science
  2. ↵
    1. Black DM,
    2. Cummings SR,
    3. Karpf DB
    (1996) Randomised trial of effect of alendronate on risk of fracture in women with existing vertebral fractures. Fracture Intervention Trial Research Group. Lancet 348:1535–1541.
    OpenUrlCrossRefPubMedWeb of Science
  3. ↵
    1. Fraser L,
    2. Adachi JD
    (2009) Glucocorticoid-induced osteoporosis: Treatment update and review. Ther Adv Musculoskelet Dis 1:71–85.
    OpenUrlCrossRefPubMed
  4. ↵
    1. Black DM,
    2. Cummings SR,
    3. Karpf DB,
    4. Cauley JA,
    5. Thompson DE,
    6. Nevitt MC,
    7. et al.
    (1996) Randomized trial of effect of alendronate on risk of fracture in women with existing vertebral fractures. Fracture Intervention Trial Research. Lancet 348:1535–1541.
    OpenUrlCrossRefPubMedWeb of Science
    1. Black DM,
    2. Delmas PD,
    3. Eastell R,
    4. Reid IR,
    5. Boonen S,
    6. Cauley JA,
    7. et al.
    (2007) Once-yearly zoledronic acid for treatment of postmenopausal osteoporosis. N Engl J Med 356:1809–1822.
    OpenUrlCrossRefPubMedWeb of Science
  5. ↵
    1. Black DM,
    2. Schwartz AV,
    3. Ensrud KE,
    4. Cauley JA,
    5. Levis S,
    6. Quandt SA,
    7. et al.
    (2006) Effects of continuing or stopping alendronate after 5 years of treatment: the Fracture Intervention Trial Long-term Extension (FLEX): a randomized trial. JAMA 296:2927–2938.
    OpenUrlCrossRefPubMedWeb of Science
  6. ↵
    1. Odvina CV,
    2. Zerwekh JE,
    3. Rao DS,
    4. Maalouf N,
    5. Gottschalk FA,
    6. Pak CY
    (2005) Severely suppressed bone turnover: a potential complication of alendronate therapy. J Clin Endocrinol Metab 90:1294–1301.
    OpenUrlCrossRefPubMedWeb of Science
  7. ↵
    1. Shane E,
    2. Burr D,
    3. Ebeling PR,
    4. Abrahamsen B,
    5. Adler RA,
    6. Brown TD
    (2010) Atypical subtrochanteric and diaphyseal femoral fractures: report of a task force of the American Society for Bone and Mineral Research. J Bone Miner Res 25:2267–2294.
    OpenUrlCrossRefPubMedWeb of Science
  8. ↵
    1. Jie Zhang Huifeng,
    2. Yun Nicole C
    (2011) Wright. Potential and Pitfalls of Using Large Administrative Claims Data to Study the Safety of Osteoporosis Therapies. Current Rheumatology Reports 3:273–282.
    OpenUrl
    1. Lenart BA,
    2. Lorich DG,
    3. Lane JM
    (2008) Atypical fractures of the femoral diaphysis in postmenopausal women taking alendronate. N Engl J Med 358:1304–1306.
    OpenUrlCrossRefPubMedWeb of Science
  9. ↵
    1. Mashiba T,
    2. Hirano T,
    3. Turner CH,
    4. Forwood MR,
    5. Johnston CC,
    6. Burr DB
    (2000) Suppressed bone turnover by bisphosphonates increases microdamage accumulation and reduces some biomechanical properties in dog rib. J Bone Miner Res 15:613–620.
    OpenUrlCrossRefPubMedWeb of Science
  10. ↵
    1. Mashiba T,
    2. Turner CH,
    3. Hirano T,
    4. Fowrood MR,
    5. Jacob DS,
    6. Johnston CC,
    7. et al.
    (2001) Effects of high-dose etidronate treatment on microdamage accumulation and biomechanical properties in beagle bone before occurrence of spontaneous fractures. Bone 28:524–531.
    OpenUrlCrossRefPubMedWeb of Science
  11. ↵
    1. Fukuda F,
    2. Kurinomaru N,
    3. Hijioka A
    (2014) Weekly teriparatide for delayed unions of atypical subtrochanteric femur fractures. Biol Ther 4:73–79.
    OpenUrl
  12. ↵
    1. Im GI,
    2. Lee SH
    (2015) Effect of teriparatide on healing of atypical femoral fractures: a systemic review. J Bone Metab 22:183–189.
    OpenUrlCrossRef
  13. ↵
    1. Chiang CY,
    2. Zebaze RM,
    3. Ghasem-Zadeh A,
    4. Iuliano-Burns S,
    5. Hardidge A,
    6. Seeman E
    (2013) Teriparatide improves bone quality and healing of atypical femoral fractures associated with bisphosphonate therapy. Bone 52:360–365.
    OpenUrlCrossRefPubMedWeb of Science
  14. ↵
    1. Chang ST,
    2. Tenforde AS,
    3. Grimsrud CD,
    4. O’Ryan FS,
    5. Gonzalez JR,
    6. Baer DM,
    7. et al.
    (2012) Atypical femur fractures among breast cancer and multiple myeloma patients receiving intravenous bisphosphonate therapy. Bone 51:524–527.
    OpenUrlCrossRefPubMedWeb of Science
    1. Ota S,
    2. Inoue R,
    3. Shiozaki T,
    4. Yamamoto Y,
    5. Hashimoto N,
    6. Takeda O,
    7. et al.
    (2016) Atypical femoral fracture after receiving antiresorptive drugs in breast cancer patients with bone metastasis. Breast Cancer, 10.
  15. ↵
    1. Lampropoulou-Adamidou K,
    2. Tournis S,
    3. Triantafyllopoulos IK
    (2016) Atypical femoral fracture in a beta-thalassemia major patient with previous bisphosphonate use: case report and a review of the literature. J Musculoskelet Neuronal Interact 16:75–78.
    OpenUrl
  16. ↵
    1. Shane E,
    2. Burr D,
    3. Abrahamsen B,
    4. Adler R,
    5. Brown TD,
    6. Cheung AM,
    7. et al.
    (2014) Atypical subtrochanteric and diaphyseal femoral fractures: second report of a task force of the American Society for Bone and Mineral Research. J Bone Miner Res 29:1–23.
    OpenUrlCrossRefPubMed
  17. ↵
    1. Adler RA,
    2. El-Hajj Fuleihan G,
    3. Bauer DC,
    4. Camacho PM,
    5. Clarke BL,
    6. Clines GA
    (2016) Managing osteoporosis in patients on long-term bisphosphonate treatment: Report of a Task Force of the American Society for Bone and Mineral Research. J Bone Miner Res 31:1910.
    OpenUrl
  18. ↵
    1. Schneider JP
    (2006) Should bisphosphonates be continued indefinitely? An unusual fracture in a healthy woman on long-term alendronate. Geriatrics 61:31–33.
    OpenUrlPubMed
PreviousNext
Back to top

In this issue

Saudi Medical Journal: 38 (6)
Saudi Medical Journal
Vol. 38, Issue 6
1 Jun 2017
  • Table of Contents
  • Cover (PDF)
  • Index by author
Print
Download PDF
Email Article

Thank you for your interest in spreading the word on Saudi Medical Journal.

NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.

Enter multiple addresses on separate lines or separate them with commas.
Long-term use of bisphosphonates in osteoporosis
(Your Name) has sent you a message from Saudi Medical Journal
(Your Name) thought you would like to see the Saudi Medical Journal web site.
Citation Tools
Long-term use of bisphosphonates in osteoporosis
Basmah K. Alwahhabi, Basil A. Alsuwaine
Saudi Medical Journal Jun 2017, 38 (6) 604-608; DOI: 10.15537/smj.2017.6.19793

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
Share
Long-term use of bisphosphonates in osteoporosis
Basmah K. Alwahhabi, Basil A. Alsuwaine
Saudi Medical Journal Jun 2017, 38 (6) 604-608; DOI: 10.15537/smj.2017.6.19793
Twitter logo Facebook logo Mendeley logo
  • Tweet Widget
  • Facebook Like
  • Google Plus One
Bookmark this article

Jump to section

  • Article
    • Abstract
    • Methods
    • Results
    • Discussion
    • Footnotes
    • References
  • Figures & Data
  • eLetters
  • References
  • Info & Metrics
  • PDF

Related Articles

  • No related articles found.
  • PubMed
  • Google Scholar

Cited By...

  • Long-term use of bisphosphonates in osteoporosis
  • Atypical femoral fractures and bisphosphonates
  • Google Scholar

More in this TOC Section

  • Longitudinal analysis of foodborne disease outbreaks in Saudi Arabia
  • Psychological stress and its association with bronchial asthma in Saudi Arabia
  • The factors affecting comfort and the comfort levels of patients hospitalized in the coronary intensive care unit
Show more Original Article

Similar Articles

CONTENT

  • home

JOURNAL

  • home

AUTHORS

  • home
Saudi Medical Journal

© 2025 Saudi Medical Journal Saudi Medical Journal is copyright under the Berne Convention and the International Copyright Convention.  Saudi Medical Journal is an Open Access journal and articles published are distributed under the terms of the Creative Commons Attribution-NonCommercial License (CC BY-NC). Readers may copy, distribute, and display the work for non-commercial purposes with the proper citation of the original work. Electronic ISSN 1658-3175. Print ISSN 0379-5284.

Powered by HighWire