Research ArticleOriginal Article
Open Access

Clinicopathological and prognostic significance of androgen receptor overexpression in colorectal cancer

Experience from Al-Madinah Al-Munawarah, Saudi Arabia

Abdulkader M. Albasri and Mohammed A. Elkablawy
Saudi Medical Journal September 2019, 40 (9) 893-900; DOI: https://doi.org/10.15537/smj.2019.9.24204

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Figures

  • Figure 1
    Figure 1

    Photomicrograph of different patterns of androgen receptor (AR) expression by immunohistochemistry in A) normal colonic mucosa showing a negative expression of AR, B) colorectal adenoma showing cytoplasmic expression of AR in the tumor cells, C) Colorectal carcinoma showing intense cytoplasmic expression of AR in tumor cells, and D) a control sample from prostatic adenocarcinoma showing intense nuclear expression of AR in the tumor cells. Arrows indicate cytoplasmic expression of AR.

  • Figure 2
    Figure 2

    Kaplan- Meier survival curves showing significant overall lower survival functions for high AR expression in colorectal cancer cases.

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