Article Figures & Data
Figures
- Figure 1
- Comparison of prevalence rates for hemoglobin (Hb) abnormalities between positive tests before and after establishment of the mandatory premarital screening program (MPMSP).
Tables
- Table 1
- Prevalence rates for sickle cell disease and beta-thalassemia major in Southern Region, Saudi Arabia from November 2017 to October 2020.
Hemoglobin abnormality Total* Positive test Percentage Sickle cell disease 2301 7.16 Beta-thalassemia major 5 0.01 ↵* Total High-performance liquid chromatography (HPLC) tested samples were 32130 over 3 years from November 2017 to October 2020
- Table 2
- Observed High-performance liquid chromatography (HPLC) hemoglobin fractions among the tested population over 3 years from November 2017 to October 2020.
Hemoglobin fraction Mean (%) Median (%) Normal Range (%) Birth 2 years - adulthood Hb A 53.74 61.60 10–40 >95 Hb A2 3.50 3.40 0.3-0.4 <3.5 Hb F 5.80 1.80 60–90 1–2 Hb S 37.00 33.40 0 0 - Table 3
- Prevalence rates for sickle cell disease, sickle cell trait, ß-thalassemia major and ß-thalassemia minor over time in Southern Region, Saudi Arabia from November 2017 to October 2020.
Hemoglobin abnormality Number of positive tests per year November 2017 - October 2018 (n=9701) November 2018 - October 2019 (n=13950) November 2019 - October 2020 (n=8481) Positive test n (%) Positive test n (%) Positive test n (%) Sickle cell disease 657 (6.77) 1000 (7.17) 645 (7.61) Sickle cell trait 659 (6.79) 1009 (7.23) 585 (6.90) Beta-thalassemia major 2 (0.02) 1 (0.01) 2 (0.02) Beta-thalassemia minor 346 (3.57) 385 (2.76) 292 (3.44)
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