Research ArticleOriginal Article
Open Access

The outcome of prevention of mother-to-child transmission of HIV infection at King Abdulaziz University Hospital, Western Region of Saudi Arabia

A Descriptive Study

Elaf H. Ahmed, Mayar A. Shafei, Leena S. Alsubhi, Noora A. Zarban, Bashair A. Al-Zahrani and Mohammed Shaikhomer
Saudi Medical Journal September 2021, 42 (9) 1009-1016; DOI: https://doi.org/10.15537/smj.2021.42.9.20200789

References

  1. 1.↵
    1. Mondal MNI,
    2. Shitan M.
    Factors affecting the HIV/AIDS epidemic: an ecological analysis of global data. Afr Health Sci 2013; 13: 301–310.
    OpenUrlCrossRef
  2. 2.↵
    1. Madani TA,
    2. Al-Mazrou YY,
    3. Al-Jeffri MH,
    4. Al Huzaim NS.
    Epidemiology of the human immunodeficiency virus in Saudi Arabia; 18-year surveillance results and prevention from an Islamic perspective. BMC Infect Dis 2004; 4: 25.
    OpenUrlCrossRefPubMed
  3. 3.↵
    1. Sennaroglu L,
    2. Bajin MD.
    Management of stapes footplate fistula in inner ear malformations. International Journal of Pediatric Otorhinolaryngology 2021; 140: 110525.
    OpenUrl
  4. 4.↵
    1. Patel D,
    2. Johnson CH,
    3. Krueger A,
    4. Maciak B,
    5. Belcher L,
    6. Harris N,
    7. DiNenno EA.
    Trends in HIV testing among US adults, aged 18-64 years, 2011-2017. AIDS Behav 2020; 24: 532–539.
    OpenUrl
  5. 5.↵
    1. Almilaibary AA.
    A mixed methods study of the factors associated with HIV testing uptake among young people in Saudi Arabia. Academic Journals 2018; 10: 96–102.
    OpenUrl
  6. 6.↵
    1. Vrazo AC,
    2. Sullivan D,
    3. Phelps BR.
    Eliminating mother-to-child transmission of HIV by 2030: 5 strategies to ensure continued progress. Glob Health Sci Pract 2018; 6: 249–256.
    OpenUrlFREE Full Text
  7. 7.↵
    1. Barral MFM,
    2. de Oliveira GR,
    3. Lobato RC,
    4. Mendoza-Sassi RA,
    5. Martínez AMB,
    6. Gonçalves CV.
    Risk factors of HIV-1 vertical transmission (VT) and the influence of antiretroviral therapy (ART) in pregnancy outcome. Rev Inst Med Trop Sao Paulo 2014; 56: 133–138.
    OpenUrl
  8. 8.↵
    1. Arora N,
    2. Sadovsky Y,
    3. Dermody TS,
    4. Coyne CB.
    Microbial vertical transmission during human pregnancy. Cell Host Microbe 2017; 21: 561–567.
    OpenUrlCrossRefPubMed
  9. 9.↵
    1. Chen X,
    2. Laurent S,
    3. Onur OA,
    4. Kleineberg NN,
    5. Fink GR,
    6. Schweitzer F, et al.
    A systematic review of neurological symptoms and complications of COVID-19. J Neurol 2021; 268: 392–402.
    OpenUrl
  10. 10.↵
    1. Connor EM,
    2. Sperling RS,
    3. Gelber R,
    4. Kiselev P,
    5. Scott G,
    6. O’Sullivan MJ, et al.
    Reduction of maternal-infant transmission of human immunodeficiency virus type 1 with zidovudine treatment. Pediatric AIDS Clinical Trials Group Protocol 076 Study Group. N Engl J Med 1994; 331: 1173–1180.
    OpenUrlCrossRefPubMedWeb of Science
  11. 11.↵
    1. Townsend CL,
    2. Cortina-Borja M,
    3. Peckham CS,
    4. de Ruiter A,
    5. Lyall H,
    6. Tookey PA.
    Low rates of mother-to-child transmission of HIV following effective pregnancy interventions in the United Kingdom and Ireland, 2000-2006. AIDS 2008; 22: 973–981.
    OpenUrlCrossRefPubMedWeb of Science
  12. 12.↵
    1. Myer L,
    2. Phillips TK,
    3. McIntyre JA,
    4. Hsiao NY,
    5. Petro G,
    6. Zerbe A,
    7. Ramjith J,
    8. Bekker LG,
    9. Abrams EJ.
    HIV viraemia and mother-to-child transmission risk after antiretroviral therapy initiation in pregnancy in Cape Town, South Africa. HIV Med 2017; 18: 80–88.
    OpenUrlCrossRef
  13. 13.↵
    1. Read PJ,
    2. Mandalia S,
    3. Khan P,
    4. Harrisson U,
    5. Naftalin C,
    6. Gilleece Y, et al.
    When should HAART be initiated in pregnancy to achieve an undetectable HIV viral load by delivery? AIDS 2012; 26: 1095–1103.
    OpenUrlCrossRefPubMedWeb of Science
  14. 14.↵
    1. Cooper ER,
    2. Charurat M,
    3. Mofenson L,
    4. Hanson IC,
    5. Pitt J,
    6. Diaz C, et al.
    Combination antiretroviral strategies for the treatment of pregnant HIV-1-infected women and prevention of perinatal HIV-1 transmission. J Acquir Immune Defic Syndr 2002; 29: 484–494.
    OpenUrlCrossRefPubMedWeb of Science
  15. 15.↵
    Achievements in public health. Reduction in perinatal transmission of HIV infection--United States, 1985-2005. MMWR Morb Mortal Wkly Rep 2006; 55: 592–597.
    OpenUrlPubMed
  16. 16.↵
    1. Boer K,
    2. Nellen JF,
    3. Patel D,
    4. Timmermans S,
    5. Tempelman C,
    6. Wibaut M, et al.
    The AmRo study: pregnancy outcome in HIV-1-infected women under effective highly active antiretroviral therapy and a policy of vaginal delivery. BJOG 2007; 114: 148–155.
    OpenUrlCrossRefPubMedWeb of Science
  17. 17.↵
    1. Scott GB,
    2. Brogly SB,
    3. Muenz D,
    4. Stek AM,
    5. Read JS
    , International Maternal Pediatric Adolescent AIDS Clinical Trials Group, P1025 Study Team. Missed opportunities for prevention of mother-to-child transmission of human immunodeficiency virus. Obstet Gynecol 2017; 129: 621–628.
    OpenUrl
  18. 18.↵
    1. Siemieniuk RA,
    2. Jadavji T,
    3. Gill MJ.
    Limitations of opt-out HIV screening and mother-child HIV transmission. Am J Public Health 2010; 100: 388–389; author reply 389.
    OpenUrlCrossRefPubMed
  19. 19.↵
    1. Shargie MB,
    2. Eek F,
    3. Abaychew A.
    Prophylactic treatment uptake and compliance with recommended follow up among HIV exposed infants: a retrospective study in Addis Ababa, Ethiopia. BMC Res Notes 2011; 4: 563.
    OpenUrlPubMed
  20. 20.↵
    1. Sibanda EL,
    2. Weller IV,
    3. Hakim JG,
    4. Cowan FM.
    The magnitude of loss to follow-up of HIV-exposed infants along the prevention of mother-to-child HIV transmission continuum of care: a systematic review and meta-analysis. AIDS 2013; 27: 2787–2797.
    OpenUrlCrossRefPubMed
  21. 21.↵
    American College of Obstetricians and Gynecologists. Labor and delivery management of women with human immunodeficiency virus infection. [Updte 2018; Access 2020 Sept 4]. Available from: https://www.acog.org/clinical/clinical-guidance/committee-opinion/articles/2018/09/labor-and-delivery-management-of-women-with-human-immunodeficiency-virus-infection
  22. 22.↵
    1. Tudor Car L,
    2. van-Velthoven MH,
    3. Brusamento S,
    4. Elmoniry H,
    5. Car J,
    6. Majeed A, et al.
    Integrating prevention of mother-to-child HIV transmission (PMTCT) programmes with other health services for preventing HIV infection and improving HIV outcomes in developing countries. PLoS One 2012; 7: e35268.
    OpenUrlCrossRefPubMed
  23. 23.↵
    1. Farquhar C,
    2. Kiarie JN,
    3. Richardson BA,
    4. Kabura MN,
    5. John FN,
    6. Nduati RW, et al.
    Antenatal couple counseling increases uptake of interventions to prevent HIV-1 transmission. Journal of acquired immune deficiency syndromes (1999). J Acquir Immune Defic Syndr 2004; 37: 1620–1626.
    OpenUrlCrossRefPubMedWeb of Science
  24. 24.↵
    1. Thomson KA,
    2. Cheti EO,
    3. Reid T.
    Implementation and outcomes of an active defaulter tracing system for HIV, prevention of mother to child transmission of HIV (PMTCT), and TB patients in Kibera, Nairobi, Kenya. Trans R Soc Trop Med Hyg 2011; 105: 320–326.
    OpenUrlCrossRefPubMed
  25. 25.↵
    1. Kundu CK,
    2. Samanta M,
    3. Sarkar M,
    4. Bhattacharyya S,
    5. Chatterjee S.
    Food supplementation as an incentive to improve pre-antiretroviral therapy clinic adherence in HIV-positive children--experience from eastern India. J Trop Pediatr 2012; 58: 31–37.
    OpenUrlCrossRefPubMedWeb of Science
  26. 26.↵
    1. Jani IV,
    2. Meggi B,
    3. Loquiha O,
    4. Tobaiwa O,
    5. Mudenyanga C,
    6. Zitha A,
    7. Mutsaka D,
    8. Mabunda N,
    9. Vubil A,
    10. Bollinger T,
    11. Vojnov L.
    Effect of point-of-care early infant diagnosis on antiretroviral therapy initiation and retention of patients. AIDS 2018; 32: 1453–1463.
    OpenUrlCrossRefPubMed
  27. 27.↵
    1. Kiyaga C,
    2. Narayan V,
    3. McConnell I,
    4. Elyanu P,
    5. Kisaakye LN,
    6. Kekitiinwa A, et al.
    Retention outcomes and drivers of loss among HIV-exposed and infected infants in Uganda: a retrospective cohort study. BMC Infect Dis 2018; 18: 416.
    OpenUrl
  28. 28.↵
    1. Edathodu J,
    2. Halim MM,
    3. Dahham MB,
    4. Alrajhi AA.
    Mother-to-child transmission of HIV: experience at a referral hospital in Saudi Arabia. Ann Saudi Med 2010; 30: 15–17.
    OpenUrlPubMed
  29. 29.↵
    1. Fageeh WM.
    Should We Screen for HIV in Saudi Arabia?. JKAU: Med Sci 2010; 17: 45–54.
    OpenUrl
  30. 30.↵
    Bureau of Experts at the Council of Ministers. Attached to the system for the prevention of acquired immune deficiency syndrome (AIDS) and the rights and duties of sufferers. [Update 2018, Access 2020 Sept 4]. Available from: https://laws.boe.gov.sa/BoeLaws/Laws/Viewer/bd60c847-2450-4d5a-a215-a9ed0119f68b?lawId=9d240ae2-a709-48ee-ac82-a9ed0119f62d.
  31. 31.↵
    1. Mazroa MAAI,
    2. Kabbash IA,
    3. Felemban SM,
    4. Stephens GM,
    5. Al-Hakeem RF,
    6. Zumla AI, et al.
    HIV case notification rates in the Kingdom of Saudi Arabia over the past decade (2000-2009). PLoS One 2012; 7: e45919.
    OpenUrlPubMed
  32. 32.↵
    UN Habitat. Saudi Arabia - Urban Issues [Update 2021; Accessed 2020 Sept 4]. Available from: https://unhabitat.org/saudi-arabia-urban-issues.
  33. 33.↵
    Association of Public Health Laboratories. Limitations for the use of HIV-1 western blot in plasma/serum. [cited 2015]. Available from: https://www.aphl.org/aboutAPHL/publications/Documents/ID_HIV-1-1-WesternBlotBrief_62015.pdf
  34. 34.
    1. Styer LM,
    2. Sullivan TJ,
    3. Parker MM.
    Evaluation of an alternative supplemental testing strategy for HIV diagnosis by retrospective analysis of clinical HIV testing data. J Clin Virol 2011; 52 Suppl 1: S35–S40.
    OpenUrl
  35. 35.
    1. Masciotra S,
    2. McDougal JS,
    3. Feldman J,
    4. Sprinkle P,
    5. Wesolowski L,
    6. Owen SM.
    Evaluation of an alternative HIV diagnostic algorithm using specimens from seroconversion panels and persons with established HIV infections. J Clin Virol 2011; 52 Suppl 1: S17–S22.
    OpenUrl
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