Skip to main content

Main menu

  • Home
  • Content
    • Latest
    • Archive
    • home
  • Info for
    • Authors
    • Reviewers
    • Subscribers
    • Institutions
    • Advertisers
    • Join SMJ
  • About Us
    • About Us
    • Editorial Office
    • Editorial Board
  • More
    • Advertising
    • Alerts
    • Feedback
    • Folders
    • Help
  • Other Publications
    • NeuroSciences Journal

User menu

  • My alerts
  • Log in

Search

  • Advanced search
Saudi Medical Journal
  • Other Publications
    • NeuroSciences Journal
  • My alerts
  • Log in
Saudi Medical Journal

Advanced Search

  • Home
  • Content
    • Latest
    • Archive
    • home
  • Info for
    • Authors
    • Reviewers
    • Subscribers
    • Institutions
    • Advertisers
    • Join SMJ
  • About Us
    • About Us
    • Editorial Office
    • Editorial Board
  • More
    • Advertising
    • Alerts
    • Feedback
    • Folders
    • Help
  • Follow psmmc on Twitter
  • Visit psmmc on Facebook
  • RSS
Research ArticleOriginal Articles
Open Access

The effect of wet-cupping therapy (hijama) in modulating autoimmune activity of Hashimoto’s thyroiditis

A pilot controlled study

Amal M. Obeid, Faiza A. Qari, Soad K. Aljaouni, Sawsan Rohaiem, Ahmed A. Elsayed, Maha M. Alsayyad and Ezzuddin A. Okmi
Saudi Medical Journal January 2022, 43 (1) 45-52; DOI: https://doi.org/10.15537/smj.2022.43.1.20210755
Amal M. Obeid
From the Department of YAJ chair for Prophetic medical applications (Obeid, Alsayyad), Cupping Therapy Clinics; from the Department of Hematology (Aljaouni), Yousef Abdulatif Jameel Scientific Chair of Prophetic Medicine Application, from the Department of Medicine (Qari); from the Department of Physiology (Rohaiem); From the Faculty of Medicine (Alsayyad), King Abdulaziz University, Jeddah, from the Department of Communicable Diseases Prevention and Control (Okmi), Public Health Authority, Riyadh, Kingdom of Saudi Arabia, and from the Department of Radiology (Elsayed), The Royal Wolverhampton Trust, New Cross Hospital, London, United Kingdom.
MD
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Faiza A. Qari
From the Department of YAJ chair for Prophetic medical applications (Obeid, Alsayyad), Cupping Therapy Clinics; from the Department of Hematology (Aljaouni), Yousef Abdulatif Jameel Scientific Chair of Prophetic Medicine Application, from the Department of Medicine (Qari); from the Department of Physiology (Rohaiem); From the Faculty of Medicine (Alsayyad), King Abdulaziz University, Jeddah, from the Department of Communicable Diseases Prevention and Control (Okmi), Public Health Authority, Riyadh, Kingdom of Saudi Arabia, and from the Department of Radiology (Elsayed), The Royal Wolverhampton Trust, New Cross Hospital, London, United Kingdom.
MD
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Soad K. Aljaouni
From the Department of YAJ chair for Prophetic medical applications (Obeid, Alsayyad), Cupping Therapy Clinics; from the Department of Hematology (Aljaouni), Yousef Abdulatif Jameel Scientific Chair of Prophetic Medicine Application, from the Department of Medicine (Qari); from the Department of Physiology (Rohaiem); From the Faculty of Medicine (Alsayyad), King Abdulaziz University, Jeddah, from the Department of Communicable Diseases Prevention and Control (Okmi), Public Health Authority, Riyadh, Kingdom of Saudi Arabia, and from the Department of Radiology (Elsayed), The Royal Wolverhampton Trust, New Cross Hospital, London, United Kingdom.
MD
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Sawsan Rohaiem
From the Department of YAJ chair for Prophetic medical applications (Obeid, Alsayyad), Cupping Therapy Clinics; from the Department of Hematology (Aljaouni), Yousef Abdulatif Jameel Scientific Chair of Prophetic Medicine Application, from the Department of Medicine (Qari); from the Department of Physiology (Rohaiem); From the Faculty of Medicine (Alsayyad), King Abdulaziz University, Jeddah, from the Department of Communicable Diseases Prevention and Control (Okmi), Public Health Authority, Riyadh, Kingdom of Saudi Arabia, and from the Department of Radiology (Elsayed), The Royal Wolverhampton Trust, New Cross Hospital, London, United Kingdom.
MD
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Ahmed A. Elsayed
From the Department of YAJ chair for Prophetic medical applications (Obeid, Alsayyad), Cupping Therapy Clinics; from the Department of Hematology (Aljaouni), Yousef Abdulatif Jameel Scientific Chair of Prophetic Medicine Application, from the Department of Medicine (Qari); from the Department of Physiology (Rohaiem); From the Faculty of Medicine (Alsayyad), King Abdulaziz University, Jeddah, from the Department of Communicable Diseases Prevention and Control (Okmi), Public Health Authority, Riyadh, Kingdom of Saudi Arabia, and from the Department of Radiology (Elsayed), The Royal Wolverhampton Trust, New Cross Hospital, London, United Kingdom.
MD
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Maha M. Alsayyad
From the Department of YAJ chair for Prophetic medical applications (Obeid, Alsayyad), Cupping Therapy Clinics; from the Department of Hematology (Aljaouni), Yousef Abdulatif Jameel Scientific Chair of Prophetic Medicine Application, from the Department of Medicine (Qari); from the Department of Physiology (Rohaiem); From the Faculty of Medicine (Alsayyad), King Abdulaziz University, Jeddah, from the Department of Communicable Diseases Prevention and Control (Okmi), Public Health Authority, Riyadh, Kingdom of Saudi Arabia, and from the Department of Radiology (Elsayed), The Royal Wolverhampton Trust, New Cross Hospital, London, United Kingdom.
MD
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Ezzuddin A. Okmi
From the Department of YAJ chair for Prophetic medical applications (Obeid, Alsayyad), Cupping Therapy Clinics; from the Department of Hematology (Aljaouni), Yousef Abdulatif Jameel Scientific Chair of Prophetic Medicine Application, from the Department of Medicine (Qari); from the Department of Physiology (Rohaiem); From the Faculty of Medicine (Alsayyad), King Abdulaziz University, Jeddah, from the Department of Communicable Diseases Prevention and Control (Okmi), Public Health Authority, Riyadh, Kingdom of Saudi Arabia, and from the Department of Radiology (Elsayed), The Royal Wolverhampton Trust, New Cross Hospital, London, United Kingdom.
MD
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • For correspondence: [email protected]
  • Article
  • Figures & Data
  • eLetters
  • Info & Metrics
  • References
  • PDF
Loading

Article Figures & Data

Figures

  • Tables
  • Figure 1
    • Download figure
    • Open in new tab
    • Download powerpoint
    Figure 1

    - Change in thyroiditis serum markers from baseline to 3 weeks post Hijama in the interventional group. TPO: thyroid peroxidase, TG: thyroglobulin, T4: thyroxine 4, TSH: thyroid stimulating hormone, ESR: erythrocyte sedi-mentation rate, *statistical significance in parametric or nonparametric, **statistical significance in both parametric and nonparametric tests

  • Figure 2
    • Download figure
    • Open in new tab
    • Download powerpoint
    Figure 2

    - Morphological changes in thyroid ultrasound assessments in hijama group.

Tables

  • Figures
    • View popup
    Table 1

    - Effect of a 3-wet-cupping therapy (hijama) sessions at 3 weeks interval on TPO and TG levels in Hashimoto’s thyroiditis by comparison to usual care.

    Markers/timeHijama group (n=13)Control group (n=13)Mean differencep-value
     Mean±SDRangeMean±SDRangePar.Npar.
    TPO       
     Baseline153.00±264.550.15-813.58301.93±304.827.14-1000-148.930.2190.047*
     Outcome86.20±185.630.01-662.86397.76±396.237.42-1000-311.570.026*0.015*
     Change-60.47±129.61-98.95±173.95--159.430.030*0.067
    TG       
     Baseline314.06±349.753.85-1078.00199.09±365.574.30-444.30114.970.4920.177
     Outcome84.99±106.581.83-338.08227.48±349.534.69-486.50-142.860.2160.492
     Change-229.06±273.38 28.39±27.27-257.450.017*<0.001*
    • TPO: thyroid peroxidase, TG: thyroglobulin, SD: standard deviation, Par: parametric (independent t-test), Npar: nonparametric (Mann Whitney-U test), *statistically significant result (2-tailed p-value of <0.05)

    • View popup
    Table 2

    - Evolution of thyroiditis serum markers in hijama group (paired analysis, n=9).

    ParametersBefore hijamaAfter hijamaMean changep-value
     Mean±SD Par.Npar.
    Prolactin331.58±129.43211.73±62.18-119.850.045*0.028*
    TPO150.84±252.3594.74±184.49-56.100.1470.003*
    TG197.14±338.5989.16±102.64-207.970.022*0.013*
    ESR112.80±197.6473.60±131.64-39.200.2560.043*
    T415.08±1.9915.11±3.090.030.9630.342
    TSH5.47±5.643.48±3.73-1.990.008*0.195
    • SD: standard deviation, Par: parametric (paired t-test), Npar: nonparametric (Wilcoxon signed rank test), TPO: thyroid peroxidase, TG: thyroglobulin, ESR: erythrocyte sedi-mentation rate, T4: thyroxine 4, TSH: thyroid stimulating hormone, *statistically significant result (2-tailed p-value of <0.05)

    • View popup
    Table 3

    - Evolution of TPO and TG in usual care group (paired analysis, n=9).

    ParametersBaselineAt 3 monthsMean changep-value
     Mean±SD Par.Npar.
    TPO298.81±338.23397.76±396.2398.950.1260.263
    TG199.09±356.67227.48±349.5328.390.022*0.018*
    • TPO: thyroid peroxidase, TG: thyroglobulin, SD: standard deviation, Par: parametric (paired t-test), Npar: nonparametric (Wilcoxon signed rank test), *statistically significant result (2-tailed p-value of <0.05)

    • View popup
    Table 4

    - Clinical changes after 3 hijama sessions among patients with Hashimoto’s disease.

    PatientsHairvoiceMoodConstipationPeriod regularity Precentage (%)Energy levelConcentration abilitySleep disturbance
    1--506050905070
    2-----50--
    3---100100100100100
    450----50--
    5----10050--
    65050-5050505050
    75050-5050505050
    8-----505050
    9--505050505050
    1050---50--50
    11---100100--50
    12        
    13--506050905070
PreviousNext
Back to top

In this issue

Saudi Medical Journal: 43 (1)
Saudi Medical Journal
Vol. 43, Issue 1
1 Jan 2022
  • Table of Contents
  • Cover (PDF)
  • Index by author
Print
Download PDF
Email Article

Thank you for your interest in spreading the word on Saudi Medical Journal.

NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.

Enter multiple addresses on separate lines or separate them with commas.
The effect of wet-cupping therapy (hijama) in modulating autoimmune activity of Hashimoto’s thyroiditis
(Your Name) has sent you a message from Saudi Medical Journal
(Your Name) thought you would like to see the Saudi Medical Journal web site.
Citation Tools
The effect of wet-cupping therapy (hijama) in modulating autoimmune activity of Hashimoto’s thyroiditis
Amal M. Obeid, Faiza A. Qari, Soad K. Aljaouni, Sawsan Rohaiem, Ahmed A. Elsayed, Maha M. Alsayyad, Ezzuddin A. Okmi
Saudi Medical Journal Jan 2022, 43 (1) 45-52; DOI: 10.15537/smj.2022.43.1.20210755

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
Share
The effect of wet-cupping therapy (hijama) in modulating autoimmune activity of Hashimoto’s thyroiditis
Amal M. Obeid, Faiza A. Qari, Soad K. Aljaouni, Sawsan Rohaiem, Ahmed A. Elsayed, Maha M. Alsayyad, Ezzuddin A. Okmi
Saudi Medical Journal Jan 2022, 43 (1) 45-52; DOI: 10.15537/smj.2022.43.1.20210755
Twitter logo Facebook logo Mendeley logo
  • Tweet Widget
  • Facebook Like
  • Google Plus One
Bookmark this article

Jump to section

  • Article
    • Abstract
    • Methods
    • Results
    • Discussion
    • Acknowledgment
    • Footnotes
    • References
  • Figures & Data
  • eLetters
  • References
  • Info & Metrics
  • PDF

Related Articles

  • No related articles found.
  • PubMed
  • Google Scholar

Cited By...

  • Prophetic Medicine in the Context of Middle Eastern Culture: A Concept Analysis
  • The effect of wet-cupping therapy (hijama) in modulating autoimmune activity of Hashimotos thyroiditis.: A pilot controlled study
  • Google Scholar

More in this TOC Section

  • Emotional responses and coping strategies of medical students during the COVID-19 pandemic
  • Childhood nephrolithiasis and nephrocalcinosis caused by metabolic diseases and renal tubulopathy
  • The antimicrobial activity of ceftobiprole against Methicillin-resistant Staphylococcus aureus and multi-drug resistant Pseudomonas aeruginosa
Show more Original Articles

Similar Articles

Keywords

  • hijama
  • cupping
  • Hashimoto’s thyroiditis
  • thyroiditis
  • thyroid gland

CONTENT

  • home

JOURNAL

  • home

AUTHORS

  • home
Saudi Medical Journal

© 2025 Saudi Medical Journal Saudi Medical Journal is copyright under the Berne Convention and the International Copyright Convention.  Saudi Medical Journal is an Open Access journal and articles published are distributed under the terms of the Creative Commons Attribution-NonCommercial License (CC BY-NC). Readers may copy, distribute, and display the work for non-commercial purposes with the proper citation of the original work. Electronic ISSN 1658-3175. Print ISSN 0379-5284.

Powered by HighWire