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Research ArticleOriginal Article
Open Access

Effect of bariatric surgery on cardiac function in obese patients

An echocardiographic assessment

Mansur S. Alqunai, Bandar S. Assakran, Adel M. Widyan, Annie Suresh, Abdullah A. Alharbi, Osamah I. Almosallam, Abdullah H. Alromaih, Abdulrahman H. Alashkar, Daliyah F. Alotaibi and Rami M. Abazid
Saudi Medical Journal June 2022, 43 (6) 587-591; DOI: https://doi.org/10.15537/smj.2022.6.20220136
Mansur S. Alqunai
From the Department of Surgery (Alqunai, Assakran, Alharbi, Alromaih), King Fahad Specialist Hospital, Ministry of Health, Buraidah, Qassim; from the Department of Mathematics (Widyan), College of Science, from the Department of Surgery (Almosallam, Alotaibi), College of Medicine, Qassim University; from the Department of Non-invasive Cardiology (Suresh), Prince Sultan Cardiac Center; from the Department of Surgery (Alashkar), Doctor Sulaiman AlHabib Medical Group, Qassim; from the Department of Surgery (Alqunai), College of Medicine, Jouf University, Aljouf, Kingdom of Saudi Arabia; and from the Division of Cardiology (Abazid), London Health Sciences Centre, University Hospital, Ontario, Canada.
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  • For correspondence: [email protected]
Bandar S. Assakran
From the Department of Surgery (Alqunai, Assakran, Alharbi, Alromaih), King Fahad Specialist Hospital, Ministry of Health, Buraidah, Qassim; from the Department of Mathematics (Widyan), College of Science, from the Department of Surgery (Almosallam, Alotaibi), College of Medicine, Qassim University; from the Department of Non-invasive Cardiology (Suresh), Prince Sultan Cardiac Center; from the Department of Surgery (Alashkar), Doctor Sulaiman AlHabib Medical Group, Qassim; from the Department of Surgery (Alqunai), College of Medicine, Jouf University, Aljouf, Kingdom of Saudi Arabia; and from the Division of Cardiology (Abazid), London Health Sciences Centre, University Hospital, Ontario, Canada.
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Adel M. Widyan
From the Department of Surgery (Alqunai, Assakran, Alharbi, Alromaih), King Fahad Specialist Hospital, Ministry of Health, Buraidah, Qassim; from the Department of Mathematics (Widyan), College of Science, from the Department of Surgery (Almosallam, Alotaibi), College of Medicine, Qassim University; from the Department of Non-invasive Cardiology (Suresh), Prince Sultan Cardiac Center; from the Department of Surgery (Alashkar), Doctor Sulaiman AlHabib Medical Group, Qassim; from the Department of Surgery (Alqunai), College of Medicine, Jouf University, Aljouf, Kingdom of Saudi Arabia; and from the Division of Cardiology (Abazid), London Health Sciences Centre, University Hospital, Ontario, Canada.
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Annie Suresh
From the Department of Surgery (Alqunai, Assakran, Alharbi, Alromaih), King Fahad Specialist Hospital, Ministry of Health, Buraidah, Qassim; from the Department of Mathematics (Widyan), College of Science, from the Department of Surgery (Almosallam, Alotaibi), College of Medicine, Qassim University; from the Department of Non-invasive Cardiology (Suresh), Prince Sultan Cardiac Center; from the Department of Surgery (Alashkar), Doctor Sulaiman AlHabib Medical Group, Qassim; from the Department of Surgery (Alqunai), College of Medicine, Jouf University, Aljouf, Kingdom of Saudi Arabia; and from the Division of Cardiology (Abazid), London Health Sciences Centre, University Hospital, Ontario, Canada.
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Abdullah A. Alharbi
From the Department of Surgery (Alqunai, Assakran, Alharbi, Alromaih), King Fahad Specialist Hospital, Ministry of Health, Buraidah, Qassim; from the Department of Mathematics (Widyan), College of Science, from the Department of Surgery (Almosallam, Alotaibi), College of Medicine, Qassim University; from the Department of Non-invasive Cardiology (Suresh), Prince Sultan Cardiac Center; from the Department of Surgery (Alashkar), Doctor Sulaiman AlHabib Medical Group, Qassim; from the Department of Surgery (Alqunai), College of Medicine, Jouf University, Aljouf, Kingdom of Saudi Arabia; and from the Division of Cardiology (Abazid), London Health Sciences Centre, University Hospital, Ontario, Canada.
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Osamah I. Almosallam
From the Department of Surgery (Alqunai, Assakran, Alharbi, Alromaih), King Fahad Specialist Hospital, Ministry of Health, Buraidah, Qassim; from the Department of Mathematics (Widyan), College of Science, from the Department of Surgery (Almosallam, Alotaibi), College of Medicine, Qassim University; from the Department of Non-invasive Cardiology (Suresh), Prince Sultan Cardiac Center; from the Department of Surgery (Alashkar), Doctor Sulaiman AlHabib Medical Group, Qassim; from the Department of Surgery (Alqunai), College of Medicine, Jouf University, Aljouf, Kingdom of Saudi Arabia; and from the Division of Cardiology (Abazid), London Health Sciences Centre, University Hospital, Ontario, Canada.
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Abdullah H. Alromaih
From the Department of Surgery (Alqunai, Assakran, Alharbi, Alromaih), King Fahad Specialist Hospital, Ministry of Health, Buraidah, Qassim; from the Department of Mathematics (Widyan), College of Science, from the Department of Surgery (Almosallam, Alotaibi), College of Medicine, Qassim University; from the Department of Non-invasive Cardiology (Suresh), Prince Sultan Cardiac Center; from the Department of Surgery (Alashkar), Doctor Sulaiman AlHabib Medical Group, Qassim; from the Department of Surgery (Alqunai), College of Medicine, Jouf University, Aljouf, Kingdom of Saudi Arabia; and from the Division of Cardiology (Abazid), London Health Sciences Centre, University Hospital, Ontario, Canada.
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Abdulrahman H. Alashkar
From the Department of Surgery (Alqunai, Assakran, Alharbi, Alromaih), King Fahad Specialist Hospital, Ministry of Health, Buraidah, Qassim; from the Department of Mathematics (Widyan), College of Science, from the Department of Surgery (Almosallam, Alotaibi), College of Medicine, Qassim University; from the Department of Non-invasive Cardiology (Suresh), Prince Sultan Cardiac Center; from the Department of Surgery (Alashkar), Doctor Sulaiman AlHabib Medical Group, Qassim; from the Department of Surgery (Alqunai), College of Medicine, Jouf University, Aljouf, Kingdom of Saudi Arabia; and from the Division of Cardiology (Abazid), London Health Sciences Centre, University Hospital, Ontario, Canada.
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Daliyah F. Alotaibi
From the Department of Surgery (Alqunai, Assakran, Alharbi, Alromaih), King Fahad Specialist Hospital, Ministry of Health, Buraidah, Qassim; from the Department of Mathematics (Widyan), College of Science, from the Department of Surgery (Almosallam, Alotaibi), College of Medicine, Qassim University; from the Department of Non-invasive Cardiology (Suresh), Prince Sultan Cardiac Center; from the Department of Surgery (Alashkar), Doctor Sulaiman AlHabib Medical Group, Qassim; from the Department of Surgery (Alqunai), College of Medicine, Jouf University, Aljouf, Kingdom of Saudi Arabia; and from the Division of Cardiology (Abazid), London Health Sciences Centre, University Hospital, Ontario, Canada.
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Rami M. Abazid
From the Department of Surgery (Alqunai, Assakran, Alharbi, Alromaih), King Fahad Specialist Hospital, Ministry of Health, Buraidah, Qassim; from the Department of Mathematics (Widyan), College of Science, from the Department of Surgery (Almosallam, Alotaibi), College of Medicine, Qassim University; from the Department of Non-invasive Cardiology (Suresh), Prince Sultan Cardiac Center; from the Department of Surgery (Alashkar), Doctor Sulaiman AlHabib Medical Group, Qassim; from the Department of Surgery (Alqunai), College of Medicine, Jouf University, Aljouf, Kingdom of Saudi Arabia; and from the Division of Cardiology (Abazid), London Health Sciences Centre, University Hospital, Ontario, Canada.
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    Patients inclusion and follow up.

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    Table 1

    - Baseline characteristics.

    Variablesn (%)
    Gender (male)19 (32.2)
    Age (years), mean±SD37±12
    Body mass index (kg/m2), mean±SD45.8±7.7
    Diabetes12 (20.3)
    Hypertension9 (15.3)
    Family history of coronary artery disease6 (10.2)
    Ejection fraction, mean±SD57±4
    Diastolic dysfunction24 (41.0)
    Hemoglobin A1c, mean±SD5.962±1.17
    Cholesterol (mmol/dl), mean±SD4.427±1.07
    Triglyceride (mmol/dl), mean±SD1.673±0.79
    High-density lipoprotein (mmol/dl), mean±SD1.220±0.34

    SD: standard deviation

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      Table 2 -

      Pre- and post-operative comparison of the patient’s cohort using paired t-test and Chi-square test.

      VariablesPre-operativePost-operativeP-value
      Body mass index (kg/m2)45.8±7.732.7±60.000
      Hemoglobin A1c (%)5.9±1.25.2±0.60.0001
      Cholesterol (mmol/dl)4.4±1.14.151±1.100.014
      Triglyceride (mmol/dl)1.8±0.81.4±0.70.000
      High-density lipoprotein (mmol/dl)1.2±0.31.5±0.50.000
      10-year risk of atherosclerotic cardiovascular1.6±1.81.1±1.60.000
      Lifetime risk of atherosclerotic cardiovascular39.6±13.634.5±6.70.000
      Echocardiography parameters
      Ejection fraction57±456±80.503
      Global longitudinal strain-16.7±4-18.6±80.131
      E velocity (cm/s)59±3885±180.000
      E/A ratio7±49±20.000
      Diastolic dysfunction, n(%)24 (41)6 (10)0.000
      E/E’ ratio9.4±2.89.4±3.30.928
      LVEDD (mm)38.5±1846.5±70.002
      LVESD (mm)25±1131±50.001
      LVESV (mL)42±1840±140.314
      LVEDV (mL)98±33101±250.414
      Left ventricular mass (g)187±255168±2520.019
      Systolic septal thickness (mm)16.09±18.2113.61±3.160.302
      Diastolic septal thickness (mm)13.26±18.679.05±2.330.089
      Pulmonary artery systolic pressure (mmHg)28.95±8.6430.45±7.650.240

      Data are presented as mean ± standard deviation (SD). E/A: mitral E-wave/A-wave velocity. E/E′: tissue Doppler mitral annular diastolic velocity, LVEDD: left ventricular end diastolic diameter, LVESD: left ventricular end-systolic diameters, LVESV: left ventricular end-systolic volume, LVEDV: left ventricular end-diastolic volume

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      Effect of bariatric surgery on cardiac function in obese patients
      Mansur S. Alqunai, Bandar S. Assakran, Adel M. Widyan, Annie Suresh, Abdullah A. Alharbi, Osamah I. Almosallam, Abdullah H. Alromaih, Abdulrahman H. Alashkar, Daliyah F. Alotaibi, Rami M. Abazid
      Saudi Medical Journal Jun 2022, 43 (6) 587-591; DOI: 10.15537/smj.2022.6.20220136

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      Effect of bariatric surgery on cardiac function in obese patients
      Mansur S. Alqunai, Bandar S. Assakran, Adel M. Widyan, Annie Suresh, Abdullah A. Alharbi, Osamah I. Almosallam, Abdullah H. Alromaih, Abdulrahman H. Alashkar, Daliyah F. Alotaibi, Rami M. Abazid
      Saudi Medical Journal Jun 2022, 43 (6) 587-591; DOI: 10.15537/smj.2022.6.20220136
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      Keywords

      • bariatric surgery
      • obesity
      • left ventricular mass

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